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The map label for this gene is gpsA [H]

Identifier: 169834303

GI number: 169834303

Start: 2083890

End: 2084906

Strand: Direct

Name: gpsA [H]

Synonym: SPH_2278

Alternate gene names: 169834303

Gene position: 2083890-2084906 (Clockwise)

Preceding gene: 169832941

Following gene: 169833946

Centisome position: 92.8

GC content: 42.87

Gene sequence:

>1017_bases
ATGGAAAAACAAACCGTCGCCGTCTTGGGGCCTGGTTCTTGGGGAACCGCCCTTTCACAAGTCTTAAATGACAATGGACA
CGAGGTACGTATTTGGGGAAATCTTCCCGAGCAAATCAATGAAATTAATACACACCATACTAATAAGCACTACTTTAAAG
ATGTCGTTCTAGACGAAAATATCATTGCCTACACCGACTTAGCAGAAACATTGAAAGATGTGGATGCGATTTTGTTTGTT
GTCCCAACAAAAGTGACACGACTTGTTGCCCAGCAAGTTGCACAAACCTTGGACCATAAGGTTATCATCATGCACGCATC
AAAGGGATTAGAACCTGATAGCCATAAACGATTATCAACCATTCTTGAAGAAGAAATTCCTGAACATCTCCGTAGTGATA
TCGTCGTTGTTTCAGGGCCTAGTCATGCAGAAGAGACCATTGTGCGTGACCTAACTTTAATAACTGCTGCTTCTAAAGAT
TTACAAACAGCTCAATACGTTCAGGAGCTATTTAGTAATCACTACTTCCGACTTTATACCAATACGGATGTTATCGGGGT
TGAAACTGCTGGTGCTCTTAAAAATATTATTGCTGTCGGTGCTGGAGCTTTACATGGTCTTGGATTTGGTGATAATGCTA
AGGCAGCCATCATCGCTCGAGGTTTAGCAGAAATCACCCGCCTAGGGGTAGCACTCGGGGCCAGTCCATTGACCTATAGC
GGCTTATCTGGTGTGGGAGATTTGATCGTAACGGGAACTTCCATCCACTCTCGTAACTGGAGAGCTGGAGATGCTCTCGG
ACGAGGAGAATCCCTAGCTGATATAGAAGCTAATATGGGCATGGTAATCGAAGGAATTTCAACGACTCGAGCAGCCTATG
AACTAGCCCAAGAACTTGGAGTCTATATGCCCATTACACAGGCTATTTACCAAGTTATTTATCACGGAACCAATATCAAA
GATGCCATTTATGACATCATGAACAATGAATTTAAAGCAGAAAATGAGTGGTCTTAA

Upstream 100 bases:

>100_bases
TCGGTTTTTGTGTATTTTTCCACCATACCCCAGTAATGCAAGTGCAAAATCCCCTAGAATATGATAGAATAAGAGAAAGA
ACTCTATCAAGGAGGAAATC

Downstream 100 bases:

>100_bases
CCCTCTATAGAAAGGATTTTTATGACATCAAAAGTTAGAAAGGCAGTCATCCCTGCTGCTGGACTAGGAACTCGATTTTT
ACCAGCAACCAAGGCCCTTG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFV
VPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIK
DAIYDIMNNEFKAENEWS

Sequences:

>Translated_338_residues
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFV
VPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIK
DAIYDIMNNEFKAENEWS
>Mature_338_residues
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFV
VPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIK
DAIYDIMNNEFKAENEWS

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=353, Percent_Identity=30.5949008498584, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI24307999, Length=341, Percent_Identity=29.6187683284457, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=40.0602409638554, Blast_Score=243, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI32564399, Length=337, Percent_Identity=27.893175074184, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=345, Percent_Identity=27.8260869565217, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=345, Percent_Identity=27.8260869565217, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17507425, Length=352, Percent_Identity=26.7045454545455, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193210134, Length=337, Percent_Identity=25.2225519287834, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320181, Length=347, Percent_Identity=29.6829971181556, Blast_Score=130, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324513, Length=347, Percent_Identity=29.3948126801153, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17136204, Length=346, Percent_Identity=28.3236994219653, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136202, Length=353, Percent_Identity=28.0453257790368, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136200, Length=346, Percent_Identity=28.3236994219653, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI22026922, Length=295, Percent_Identity=24.7457627118644, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI45551945, Length=293, Percent_Identity=23.5494880546075, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281362270, Length=293, Percent_Identity=23.5494880546075, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24648969, Length=239, Percent_Identity=25.1046025104602, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36778; Mature: 36778

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDEN
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHCCCC
IIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLST
EEEHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
ILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQELFSNHYFRLYT
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELG
CCCCCCCEEEECCEEECCCCCCCCCCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHCC
VYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINTHHTNKHYFKDVVLDEN
CCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCCHHHHHHHHCCCC
IIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVIIMHASKGLEPDSHKRLST
EEEHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHH
ILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKDLQTAQYVQELFSNHYFRLYT
HHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEE
NTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAIIARGLAEITRLGVALGASPLTYS
CCCEEEEECHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIEANMGMVIEGISTTRAAYELAQELG
CCCCCCCEEEECCEEECCCCCCCCCCCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHCC
VYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAENEWS
CCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA