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The map label for this gene is ftsW [H]

Identifier: 169834283

GI number: 169834283

Start: 1059896

End: 1061125

Strand: Direct

Name: ftsW [H]

Synonym: SPH_1154

Alternate gene names: 169834283

Gene position: 1059896-1061125 (Clockwise)

Preceding gene: 169833182

Following gene: 169833797

Centisome position: 47.2

GC content: 39.35

Gene sequence:

>1230_bases
ATGAAGATTAGTAAGAGGCACTTATTAAATTATTCCATCTTGATTCCCTACTTGCTTTTATCTATTTTGGGCTTGATTGT
GGTCTATTCGACCACCAGTGCTATTTTAATTGAAGAAGGCAAGAGTGCCTTGCAGTTGGTTCGAAACCAAGGAATCTTTT
GGATTGTTAGTTTGATACTGATTGCCTTAATTTATAAATTGAGACTAGATTTTTTGAGAAATGAGCGACTAATCATTTTA
GTTATATTAATAGAAATGCTTTTATTGTTCTTGGCTCGTTTTATTGGTATTTCCGTAAACGGGGCATACGGTTGGATTTC
GGTTGCAGGAGTAACTATTCAGCCAGCTGAGTACTTAAAAATCATTATTATTTGGTATTTAGCTCACCGATTCTCCAAAC
AGCAAGAAGAAATAGCTACTTATGATTTTCAAGTTTTGACTCAAAATCAATGGCTTCCCCGTGCTTTTAATGATTGGCGA
TTCGTTCTCCTAGTTCTGATTGGAAGTTTGGGAATTTTCCCTGATTTAGGAAATGCGACTATTTTAGTCTTGGTTTCCTT
GATTATGTATACAGTTAGTGGAATCGCTTATCGCTGGTTTTCAACCATTCTGGCGCTCGTATCTGCCGCTTCTGTCTTTG
TCTTGACCACTATCAGCCTAATCGGTGTTGAGACCTTTTCAAAAATTCCAGTATTTGGCTATGTAGCCAAGCGCTTTAGT
GCCTTTTTTAATCCTTTTGCCGATCGTGCTGATGCAGGTCACCAGTTAGCTAATTCTTATTTTGCCATGGTCAATGGCAG
TTGGTTTGGTCTAGGTCTTGGAAACTCGATTGAAAAACGAGGTTATTTGCCAGAAGCTCATACAGACTTTGTCTTTTCTA
TCGTGATTGAAGAATTTGGCTTTGTTGGTGCCAGTCTTATTTTAGCTCTCTTGTTTTTCATGATTTTGCGGATTATCTTG
GTCGGTATCCGAGCGGAGAATCCTTTCAATGCCATGGTTGCACTCGGTGTCGGAGGGATGATGTTGGTTCAGGTATTTGT
CAATATCGGAGGGATTTCGGGCTTGATTCCATCTACAGGAGTGACTTTCCCCTTCTTATCCCAGGGTGGAAATAGTCTTC
TAGTCTTATCAGTGGCAGTAGCCTTTGTCTTAAATATTGATGCCAGTGAAAAACGCGCTAAGTTGTACCGAGAATTGGAA
AATCAACCAATGAACCTTCTGTTGAAGTAG

Upstream 100 bases:

>100_bases
TTTTTTTCTTTCTGAAAAAATGGTATAATAGCAATCAAAACTAGAAAATAAAACGGAATTTGGAACAGATTTATCTGTAT
CCTAGTAGAGTGGTGATGCT

Downstream 100 bases:

>100_bases
GATAAAGAAAGGATAGTTTATGTCTCTTCAAAAATTAGAAAATTATAGTAATAAAAGTGTTGTGAAAGAAGAAGTCTTGA
TTCTAACAGAATTACTGGAA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIIL
VILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTISLIGVETFSKIPVFGYVAKRFS
AFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIIL
VGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELE
NQPMNLLLK

Sequences:

>Translated_409_residues
MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIIL
VILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTISLIGVETFSKIPVFGYVAKRFS
AFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIIL
VGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELE
NQPMNLLLK
>Mature_409_residues
MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIIL
VILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTISLIGVETFSKIPVFGYVAKRFS
AFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIIL
VGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELE
NQPMNLLLK

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=379, Percent_Identity=31.6622691292876, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1786853, Length=315, Percent_Identity=29.8412698412698, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45466; Mature: 45466

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHH
IALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEECEEECHHHHHH
IIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWRFVLLVLIGSLGIFPDLGNAT
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
ILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTISLIGVETFSKIPVFGYVAKRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFG
HHHCHHHHHCCHHHHHHHHHHEEECCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHC
FVGASLILALLFFMILRIILVGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
VTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELENQPMNLLLK
CCCCHHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSALQLVRNQGIFWIVSLIL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCCHHHHHHHHH
IALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGAYGWISVAGVTIQPAEYLK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCEECCCCCCEEEEECEEECHHHHHH
IIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWRFVLLVLIGSLGIFPDLGNAT
HHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
ILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTISLIGVETFSKIPVFGYVAKRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNSIEKRGYLPEAHTDFVFSIVIEEFG
HHHCHHHHHCCHHHHHHHHHHEEECCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHC
FVGASLILALLFFMILRIILVGIRAENPFNAMVALGVGGMMLVQVFVNIGGISGLIPSTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
VTFPFLSQGGNSLLVLSVAVAFVLNIDASEKRAKLYRELENQPMNLLLK
CCCCHHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]