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The map label for this gene is yesM [H]

Identifier: 169833941

GI number: 169833941

Start: 234079

End: 235677

Strand: Direct

Name: yesM [H]

Synonym: SPH_0267

Alternate gene names: 169833941

Gene position: 234079-235677 (Clockwise)

Preceding gene: 169833193

Following gene: 169834437

Centisome position: 10.42

GC content: 41.59

Gene sequence:

>1599_bases
ATGATCATTATCATTGCGAGTTTTGCAATCTTACTCTCTTACGCTGACTGGGATTCACGTGAAAAGGAAGCCCAGAGAGT
AGCCCAGCGTGTAACTGCTAGAACAGTGAGTGAAATTGAATATTACCATAGAGAGTCAACCCAGATAGCTCAGGCTTTAG
TTGAAAATCAAGCTCGTATCGAGGGAATCTATAAATACTTTAGCCTTAGCATGCCAGACTATTTTTACTGGCAATTAGAG
CGGAAAGCTTCGCCTTATATATCAGTCTCTCTGTATGAAAATGTTGATGACCTCTATGTTCGAAATGATTTTGTAACTGG
GGTGGCCATTGCTTTTCAAGATTACAAGGAAGTCTATGTTTCTACTAAAGACAAACGTAGTGGAGAAAAAATCAGGGCTG
AGGATTTCAAACCAGCAGGAAATAGTTTTGCCATTCCAGTGTCAGATCCAGTGTCAGATCAAGACTTAGGAGTGATTTAC
ATCTCCTTGGATCCTGCTGTTTTATACCATGCCATTGATAATACTAGAGGTCATACTCCGATGGCAGTAACAGTGACCTC
ACCTTTTGATACGGAGATTTTTCATATGGGTGAGACAGTTGATAAGGAGAGTGAAAATTGGCTAGTTGGCTTAACTTCTC
ATGGTTATCAGGTTCAGGTGGCAGTTCCCAAAAACTTTGTTTTACAAGGAACGGTGACCAGCTCTGCTTTGATTGTGGGC
TTGAGCCTTCTCTTTATTGTCATTCTTTATCTGACTTTGAGGCAGACCTTTGCTAATTATCAAAAGCAGGTAGTGGATTT
GGTGGATTCCATCCAAGCTATTGCCCAAGGACAAGAAGGTCTTCGCATTGATACGCTTGAAAAGGATCAGGAATTGCTCC
TAATCGCGGAGACGACCAATGATATGTTGGATCGATTGGAAAAGAATATCCATGATATTTACCAGTTAGAACTCAGTCAA
AAAGATGCCAATATGCGGGCCTTGCAGGCGCAAATCAACCCTCACTTCATGTATAATACGCTGGAGTTCTTGCGTATGTA
CGCAGTCATGCAGAGTCAAGATGAGTTGGCAGATATCATTTATGAATTCAGTAGTCTCTTGCGTAACAATATTTCCGACG
AAAGAGAGACCCTCCTCAAACAGGAATTAGAATTTTGCCGTAAATACAGCTATCTCTGCATGGTTCGCTATCCCAAGTCC
ATTGCCTATGGTTTCAAGATAGATCCAGAGTTAGAGAATATGAAGATTCCCAAGTTTACCTTGCAACCGCTGGTAGAAAA
CTATTTCGCGCATGGTGTTGACCACAGGCGGACAGATAATGTGATTAGCATCAAGGCTCTTAAACAGGATGGGTTTGTGG
AAATTTTGGTGGTCGATAATGGTAGAGGAATGTCGGCTGAAAAGTTGGCAAATATCCGAGAAAAATTAAGTCAGAAATAT
TTTGAACACCAAGCCAGCTACAGTGATCAAAGGCAGTCTATCGGGATTGTCAATGTACACGAGCGTTTTGTGCTCTATTT
TGGAGACCGCTATGCCATTACTATAGAGTCTGCAGAGCAAGCCGGTGTTCAGTATCGTATTACAATTCAAGATGAGTAG

Upstream 100 bases:

>100_bases
ATGTTGGAACCTGTTTATGAAATCATCCATGAAAAATTGGCGACAAAATAGAATGAAGCAGTTTTGGCTACATACGCTTC
TAAGAACCTATAGTTCAGTG

Downstream 100 bases:

>100_bases
AAAGGGAGAAAATGTATAAAGTATTATTAGTAGATGATGAGTACATGGTGACAGAAGGTCTGAAGCGTTTGATTCCCTTT
GATAAGTGGGATATGGAGGT

Product: sensor histidine kinase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLE
RKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIY
ISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVG
LSLLFIVILYLTLRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLELSQ
KDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKS
IAYGFKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKY
FEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE

Sequences:

>Translated_532_residues
MIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLE
RKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIY
ISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVG
LSLLFIVILYLTLRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLELSQ
KDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKS
IAYGFKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKY
FEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE
>Mature_532_residues
MIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLE
RKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIY
ISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVG
LSLLFIVILYLTLRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLELSQ
KDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKS
IAYGFKIDPELENMKIPKFTLQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKY
FEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=197, Percent_Identity=29.9492385786802, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788446, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61203; Mature: 61203

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARI
CEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EGIYKYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYV
HHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHEEECCHHHHHHHHHHHHHHHHC
STKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTP
CCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCEEEEEEECHHHEEEECCCCCCCCC
MAVTVTSPFDTEIFHMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVG
EEEEEECCCCCHHEECCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCHHHHHHHH
LSLLFIVILYLTLRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECHH
DMLDRLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADII
HHHHHHHHHHHHHHHEEECCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
YEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHEECEEECCCCCCCCCCCHH
LQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKY
HHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
FEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE
HHHHCCCCCHHHCCCEEEECCEEEEEECCEEEEEEECHHHCCCEEEEEEECC
>Mature Secondary Structure
MIIIIASFAILLSYADWDSREKEAQRVAQRVTARTVSEIEYYHRESTQIAQALVENQARI
CEEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
EGIYKYFSLSMPDYFYWQLERKASPYISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYV
HHHHHHHHCCCCCEEEEEEECCCCCEEEEEEECCCCHHEEECCHHHHHHHHHHHHHHHHC
STKDKRSGEKIRAEDFKPAGNSFAIPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTP
CCCCCCCCCCEECCCCCCCCCEEEEECCCCCCCCCCEEEEEEECHHHEEEECCCCCCCCC
MAVTVTSPFDTEIFHMGETVDKESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVG
EEEEEECCCCCHHEECCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCHHHHHHHH
LSLLFIVILYLTLRQTFANYQKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECHH
DMLDRLEKNIHDIYQLELSQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADII
HHHHHHHHHHHHHHHEEECCCCCCHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
YEFSSLLRNNISDERETLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCHHEECEEECCCCCCCCCCCHH
LQPLVENYFAHGVDHRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKY
HHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
FEHQASYSDQRQSIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE
HHHHCCCCCHHHCCCEEEECCEEEEEECCEEEEEEECHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]