Click here to switch to the map view.

The map label for this gene is mtbP [H]

Identifier: 169833924

GI number: 169833924

Start: 67192

End: 67560

Strand: Direct

Name: mtbP [H]

Synonym: SPH_0084

Alternate gene names: 169833924

Gene position: 67192-67560 (Clockwise)

Preceding gene: 169834211

Following gene: 169832968

Centisome position: 2.99

GC content: 40.92

Gene sequence:

>369_bases
ATGTTTACGCTGACGGCACAAGACCGTCATGGGATTTTAATTAAAGAAGCAACAAAAAAAGGTTATGCAGAGGCTACAGT
TGGTGATAGTGTAAACCTATCTCATCCAAACTCTAAAACAAGGCGAGGTAGAGTTGGTAATCAGATAGCAAATACTCTCT
TAACTGGAGAGAGTCAAGGTGTGGTTGAGCCTGATTTTAGGATTAGGAAGCTAACACCTAGAGAATGCTGGAGGTTACAA
GGTTTTCCTGATTGGGCTTTTGATAAGGCGCAGGAGGTCAACTCTAACAGTCAATTATACAAGCAAGCAGGCAATAGCGT
AACAGTAAACGTTATTTCTGCAATAGCACAGGGTTTAGGAGGAAATTAA

Upstream 100 bases:

>100_bases
GATTATAAAGAGCCAAAACAAGTAGCTATACCAGTATTGACACCTGATAGAGTAAATAAACGACAGAATGGTAGACGTTT
AAAAAAAAAACGGTGAGCCT

Downstream 100 bases:

>100_bases
CCCTATTTAAACCAATTTGAAAAGGAAACAGAAAATGACAAAAATTGAAATCGTTATGGTACTTACAACTTTGATGTCTA
TCACATGGGCAGCGATTGTT

Product: hypothetical protein

Products: NA

Alternate protein names: M.Phi3TI; Cytosine-specific methyltransferase Phi3TI [H]

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MFTLTAQDRHGILIKEATKKGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPRECWRLQ
GFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN

Sequences:

>Translated_122_residues
MFTLTAQDRHGILIKEATKKGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPRECWRLQ
GFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN
>Mature_122_residues
MFTLTAQDRHGILIKEATKKGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPRECWRLQ
GFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN

Specific function: This enzyme methylates the first cytosine within the sequences GGCC and GCNGC [H]

COG id: COG0270

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 13343; Mature: 13343

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLTAQDRHGILIKEATKKGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQG
CEEECCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
VVEPDFRIRKLTPRECWRLQGFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLG
CCCCCCEEEECCHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCEEEHHHHHHHHHHCC
GN
CC
>Mature Secondary Structure
MFTLTAQDRHGILIKEATKKGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQG
CEEECCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
VVEPDFRIRKLTPRECWRLQGFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLG
CCCCCCEEEECCHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCEEEHHHHHHHHHHCC
GN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]