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The map label for this gene is obgE [H]

Identifier: 169833915

GI number: 169833915

Start: 1073220

End: 1074524

Strand: Direct

Name: obgE [H]

Synonym: SPH_1167

Alternate gene names: 169833915

Gene position: 1073220-1074524 (Clockwise)

Preceding gene: 169833087

Following gene: 169833257

Centisome position: 47.79

GC content: 43.91

Gene sequence:

>1305_bases
ATGTTTTTAGATACAGCTAAGATCAAGGTCAAGGCTGGTAATGGTGGTGATGGCATGGTTGCCTTTCGCCGTGAAAAATA
TGTCCCTAATGGTGGTCCTTGGGGTGGTGATGGTGGTCGTGGAGGCAATGTGGTCTTCGTTGTAGACGAAGGACTACGTA
CCTTGATGGATTTCCGCTACAATCGTCATTTCAAGGCTGATTCTGGTGAAAAAGGGATGACCAAAGGGATGCATGGTCGT
GGTGCTGAGGACCTTAGAGTTCGAGTACCACAAGGTACGACTGTTCGTGATGCGGAGACTGGCAAGGTTTTAACAGATTT
GATTGAACATGGGCAAGAATTTATCGTTGCCCACGGTGGTCGTGGTGGACGTGGAAATATTCGTTTCGCGACACCAAAAA
ATCCTGCACCGGAAATCTCTGAAAATGGAGAACCAGGTCAGGAACGTGAGTTACAATTGGAACTAAAAATCTTGGCAGAT
GTCGGTTTAGTAGGTTTCCCATCTGTAGGGAAATCAACACTTTTAAGTGTTATTACCTCAGCTAAACCTAAAATTGGTGC
CTACCACTTTACCACTATTGTACCAAATTTAGGTATGGTTCGCACCCAATCAGGTGAATCCTTTGCAGTAGCCGACTTGC
CAGGTTTGATTGAAGGGGCTAGTCAAGGTGTTGGTTTGGGAACTCAGTTCCTCCGTCATATCGAGCGTACACGTGTTATC
CTTCACATCATTGATATGTCAGCTAGCGAAGGCCGTGATCCATATGAGGATTACCTAGCTATCAATAAAGAGCTGGAGTC
TTACAATCTTCGCCTCATGGAGCGTCCACAGATTATTGTAGCTAATAAGATGGACATGCCTGAGAGTCAGGAAAATCTTG
AAGACTTTAAGAAAAAATTGGCTGAAAATTATGATGAATTTGAAGAGTTACCAGCTATCTTCCCAATTTCTGGATTGACC
AAGCAAGGCCTGGCAACACTTTTAGATGCTACAGCTGAATTGTTAGACAAGACACCAGAATTTTTGCTCTACGACGAGTC
CGATATGGAAGAAGAAGCTTACTATGGATTTGACGAAGAAGAAAAAGCCTTTGAAATTAGTCGTGATGACGATGCGACAT
GGGTACTTTCTGGTGAAAAACTCATGAAACTCTTTAATATGACCAACTTTGATCGTGATGAATCTGTCATGAAATTTGCC
CGTCAGCTTCGTGGTATGGGGGGTGATGAAGCCCTTCGTGCGCGTGGAGCTAAAGATGGGGATTTGGTCCGCATTGGTAA
ATTTGAGTTTGAATTTGTAGACTAG

Upstream 100 bases:

>100_bases
AACTGCAATTGGTGCCCTCAGTAATCTATAAAATAGATTCAAGAAAATTTAGTGACTGGGATTTCCCAGCCCTTTTTTAA
AGTGAGAAGAAAAAATGAGT

Downstream 100 bases:

>100_bases
GAGACTGGTATGGGAGATAAACCGATATCTTTCCGAGATGCGGATGGTAATTTTGTTTCCGCCGCAGACGTTTGGAATGA
AAAGAAATTGGAAGAACTAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGR
GAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILAD
VGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVI
LHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLT
KQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFA
RQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD

Sequences:

>Translated_434_residues
MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGR
GAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILAD
VGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVI
LHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLT
KQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFA
RQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD
>Mature_434_residues
MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGR
GAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILAD
VGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVI
LHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLT
KQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFA
RQLRGMGGDEALRARGAKDGDLVRIGKFEFEFVD

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=339, Percent_Identity=41.8879056047198, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI111955139, Length=357, Percent_Identity=35.0140056022409, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI111955063, Length=189, Percent_Identity=37.037037037037, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4758796, Length=153, Percent_Identity=36.6013071895425, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4557537, Length=121, Percent_Identity=39.6694214876033, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789574, Length=324, Percent_Identity=46.9135802469136, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=34.7826086956522, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=336, Percent_Identity=39.2857142857143, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17552324, Length=319, Percent_Identity=29.7805642633229, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=39.8305084745763, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17555344, Length=153, Percent_Identity=34.640522875817, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=31.6546762589928, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=196, Percent_Identity=38.7755102040816, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=39.6825396825397, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.8888888888889, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129375, Length=299, Percent_Identity=42.1404682274247, Blast_Score=197, Evalue=8e-51,
Organism=Drosophila melanogaster, GI24585318, Length=372, Percent_Identity=36.8279569892473, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21356473, Length=126, Percent_Identity=38.0952380952381, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17981711, Length=153, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48089; Mature: 48089

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRY
CCCCCEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
NRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCHHHHHHHHHCCCEEEEEECC
RGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILADVGLVGFPSVGKSTLLSVITS
CCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHC
AKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVI
CCCCCCEEEEEECCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
LHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKL
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHH
AENYDEFEELPAIFPISGLTKQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEE
HHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCC
EKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFARQLRGMGGDEALRARGAKDG
CHHEEECCCCCCEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCC
DLVRIGKFEFEFVD
CEEEEECEEEEECC
>Mature Secondary Structure
MFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGGNVVFVVDEGLRTLMDFRY
CCCCCEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHH
NRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAETGKVLTDLIEHGQEFIVAHGG
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCCHHHHHHHHHCCCEEEEEECC
RGGRGNIRFATPKNPAPEISENGEPGQERELQLELKILADVGLVGFPSVGKSTLLSVITS
CCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHC
AKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGLIEGASQGVGLGTQFLRHIERTRVI
CCCCCCEEEEEECCCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
LHIIDMSASEGRDPYEDYLAINKELESYNLRLMERPQIIVANKMDMPESQENLEDFKKKL
EEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHHH
AENYDEFEELPAIFPISGLTKQGLATLLDATAELLDKTPEFLLYDESDMEEEAYYGFDEE
HHCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCC
EKAFEISRDDDATWVLSGEKLMKLFNMTNFDRDESVMKFARQLRGMGGDEALRARGAKDG
CHHEEECCCCCCEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCCC
DLVRIGKFEFEFVD
CEEEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA