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The map label for this gene is yicO [C]

Identifier: 169833800

GI number: 169833800

Start: 356269

End: 357741

Strand: Direct

Name: yicO [C]

Synonym: SPH_0403

Alternate gene names: 169833800

Gene position: 356269-357741 (Clockwise)

Preceding gene: 169834425

Following gene: 169834288

Centisome position: 15.87

GC content: 40.94

Gene sequence:

>1473_bases
ATGATAAATGATATAATTCTATTATTGTTCGTAAAAATTAAAAGGAGATTGATGATGGACAAATTATTTAAACTAAAAGA
GAACGGTACAGACGTTCGTACAGAGGTTCTCGCTGGTTTAACAACTTTCTTTGCAATGAGCTATATTCTCTTTGTAAACC
CACAAATACTTTCACAAACAGGAATGCCTGCTCAGGGCGTCTTCCTAGCGACGATTATTGGTGCAGTAGCGGGTACCTTG
ATGATGGCTTTTTATGCTAACTTACCTTATGCCCAAGCGCCAGGTATGGGACTCAATGCCTTCTTTACCTTTACAGTTGT
ATTCGGGCTTGGTTATTCTTGGCAAGAAGCCCTAGCTATGGTCTTCATCTGTGGGATTATTTCATTGATTATTACCTTGA
CAAATGTTCGTAAAATGATCATTGAATCGATTCCCAATGCTCTTCGCTCAGCTATTTCAGCTGGTATCGGTGTCTTCCTT
GCCTATGTAGGGATTAAGAATGCTGGACTTTTGAAATTCACGATTGATCCAGGCAACTATACTGTTGTAGGAGAAGGGGC
TGACAAAGCTCAAGCAACGATTGCAGCAAACTCTTCAGCAGTTCCAGGATTGGTCAGCTTTAATAATCCAGCTGTTTTAG
TGGCTCTTGCAGGACTTGCCATTACTATCTTCTTTGTCATCAAAGGGATTAAAGGGGGAATTATTCTCTCTATCTTGACA
ACAACTGTTCTTGCTATTGCAGTTGGTTTGGTTGATTTGTCTAGTATCGATTTTGCTAATAACCATGTTGGTGCAGCTTT
TGAAGATTTGAAGACAATCTTTGGTGCAGCTCTTGGTTCAGAAGGTTTGGGAGCTTTGGTTTCAGATACAGCTCGCTTGC
CTGAAACTCTGATGGCCATTCTTGCCTTCTCATTGACAGATATTTTTGACACAATTGGTACCTTGATCGGTACAGGTGAA
AAAGTTGGTATTGTAGCGACAAATGGTGAAAATCACCAATCAGCCAAATTGGATAAGGCTCTTTACTCTGATTTGATTGG
AACGACAGTCGGTGCCATTGCAGGTACTTCAAACGTAACGACTTATGTTGAGTCTGCTGCTGGTATCGGTGCAGGTGGAC
GTACTGGTTTGACAGCCTTGGTTGTAGCTATCTGTTTTGCGATTTCAAGCTTCTTTAGCCCACTTCTAGCGATCGTACCA
ACAGCGGCTACAGCTCCAATCTTGATTATCGTTGGGATTATGATGCTTGGTAGCTTGAAAAATATCCATTGGGATGATAT
GTCTGAAGCAGTTCCTGCCTTCTTCACATCTATCTTTATGGGATTCAGCTACTCTATCACTCAAGGGATTGCAGTTGGTT
TCTTGACTTACACTTTGACTAAGCTTGTCAAAGGTCAAGTTAAAGATGTTCATGCCATGATTTGGATTTTGGATGCCTTG
TTTATCCTTAACTACATCAGCATGGCCTTATAA

Upstream 100 bases:

>100_bases
TTCTATTATAACAGAAAGCAGGCAGAAAAGCAGATTCCAAACAAAAAATGAAATTGGATTAATTTCTTAAACAAATCAAA
CAAAGACATTGAAAAAGTGA

Downstream 100 bases:

>100_bases
TAGAATGACCCAGGGGGATTTCCCCCCTTTTTTAATACAAAGGAGATAGGTGATGAAAGAGAAAAATATGTGGAAAGAAT
TGTTGAATCGTGCAGGCTGG

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MINDIILLLFVKIKRRLMMDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAGTL
MMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFL
AYVGIKNAGLLKFTIDPGNYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILT
TTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGTGE
KVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVP
TAATAPILIIVGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHAMIWILDAL
FILNYISMAL

Sequences:

>Translated_490_residues
MINDIILLLFVKIKRRLMMDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAGTL
MMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFL
AYVGIKNAGLLKFTIDPGNYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILT
TTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGTGE
KVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVP
TAATAPILIIVGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHAMIWILDAL
FILNYISMAL
>Mature_490_residues
MINDIILLLFVKIKRRLMMDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGMPAQGVFLATIIGAVAGTL
MMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAMVFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFL
AYVGIKNAGLLKFTIDPGNYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILT
TTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAILAFSLTDIFDTIGTLIGTGE
KVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVP
TAATAPILIIVGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHAMIWILDAL
FILNYISMAL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=468, Percent_Identity=38.6752136752137, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1790150, Length=471, Percent_Identity=38.4288747346072, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1790499, Length=454, Percent_Identity=31.4977973568282, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI48994909, Length=466, Percent_Identity=31.1158798283262, Blast_Score=179, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 51438; Mature: 51438

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDIILLLFVKIKRRLMMDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
GMPAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCE
TVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILT
EEEECCCCCHHEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAI
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVT
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGSLK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
NIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHAMIWILDAL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILNYISMAL
HHHHHHHHCC
>Mature Secondary Structure
MINDIILLLFVKIKRRLMMDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
GMPAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCE
TVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIILSILT
EEEECCCCCHHEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLPETLMAI
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGAIAGTSNVT
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
TYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILIIVGIMMLGSLK
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
NIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVKDVHAMIWILDAL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FILNYISMAL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]