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The map label for this gene is xpt [H]

Identifier: 169833722

GI number: 169833722

Start: 1823492

End: 1824073

Strand: Direct

Name: xpt [H]

Synonym: SPH_1962

Alternate gene names: 169833722

Gene position: 1823492-1824073 (Clockwise)

Preceding gene: 169833563

Following gene: 169834427

Centisome position: 81.2

GC content: 43.99

Gene sequence:

>582_bases
ATGAAATTATTAGAAGAACGCATCCTCAAGGATGGGCATATCTTGGGTGATAACATCCTCAAGGTAGATTCCTTTTTAAC
CCACCAAGTTGACTTTAGCTTGATGCGAGAGATTGGTAAGGTTTTTGCGGAAAAATTTGCTGCTACTGGCATTACCAAGG
TCGTAACCATTGAAGCATCGGGTATTGCCCCAGCCGTTTTTACAGCTGAAGCCTTAAACGTTCCCATGATTTTCGCCAAA
AAAGCTAAGAACATCACCATGAACGAAGGCATCTTAACTGCTCAAGTCTACTCCTTTACCAAACAGGTGACCAGCACCGT
TTCTATCGCTGGAAAATTCCTCTCACCAGAGGACAAGGTTTTGATTATCGACGATTTCCTTGCTAATGGCCAAGCTGCTA
AAGGCTTGATTCAAATCATCGAACAGGCCGGTGCCACAGTCCAAGCTATCGGTATCGTGATTGAGAAATCCTTCCAAGAT
GGCCGTGATTTGCTTGAAAAAGCAGGCTACCCTGTCCTATCACTTGCTCGTTTGGATCGTTTTGAAAATGGTCAGGTCGT
ATTTAAGGAGGCAGATCTCTAA

Upstream 100 bases:

>100_bases
GCTCGTAATAGTTTTATCAAATATATAGTATTAGCAAAAGGGATCACTATAGAAACATTTAAACAACAAGTAAATTAACT
TTTAGACTTTAGGAGGTCTT

Downstream 100 bases:

>100_bases
TGCAAACTCAAGAAAAACACTCGCAAGCAGCCGTTCTTGGCTTGCAGCACTTACTAGCCATGTACTCAGGATCTATCCTG
GTTCCCATCATGATTGCGAC

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAK
KAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL

Sequences:

>Translated_193_residues
MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAK
KAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL
>Mature_193_residues
MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAK
KAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR010079 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20986; Mature: 20986

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEAS
CCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKV
CCCCHHEEHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDR
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHCHHHHHHHHHHCCCCEEHHHHHHC
FENGQVVFKEADL
CCCCCEEEEECCC
>Mature Secondary Structure
MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEAS
CCHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKV
CCCCHHEEHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
LIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDR
EEEECCCCCCHHHHHHHHHHHHHCCCEEHHHHHHHHCHHHHHHHHHHCCCCEEHHHHHHC
FENGQVVFKEADL
CCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA