Click here to switch to the map view.

The map label for this gene is argS [H]

Identifier: 169833567

GI number: 169833567

Start: 2073340

End: 2075031

Strand: Direct

Name: argS [H]

Synonym: SPH_2266

Alternate gene names: 169833567

Gene position: 2073340-2075031 (Clockwise)

Preceding gene: 169832855

Following gene: 169832852

Centisome position: 92.33

GC content: 42.43

Gene sequence:

>1692_bases
ATGAATACAAAAGAATTGATTGCAAGCGAATTGGCTAGCATCATTGATAGCCTGGACCAAGAGGCTATTTTAAAGTTACT
GGAAACCCCTAAAAACTCAGAAATGGGGGACATCGCTTTCCCTGCTTTTTCTCTTGCCAAAGTCGAACGTAAAGCACCAC
AAATGATTGCGGCTGAACTGGCTGAAAAAATGAACAGCCAAGCCTTTGAAAAAGTTGTCGCAACAGGACCTTACGTTAAC
TTTTTCCTTGATAAATCTACCATTTCTGCTCAAGTATTGCAAGCTGTTACCACTGAAAAAGAACACTATGCTGACCAAAA
TATTGGTAAACAAGAAAATGTTGTTATCGACATGTCTAGTCCGAATATCGCTAAACCATTTTCTATTGGCCACCTGCGTT
CAACTGTTATCGGAGATAGCTTGTCACATATTTTCCAAAAAATCGGTTATCAAACGGTCAAGGTCAACCATTTGGGAGAC
TGGGGTAAACAATTTGGGATGTTGATTGTTGCCTACAAAAAATGGGGCGACGAAGAAGCTGTAAAAGCTCATCCAATCGA
TGAACTCCTTAAACTCTATGTCCGCATCAACGCTGAAGCTGAAAATGACCCTAGCTTGGATGAAGAAGCGCGCGAATGGT
TCCGTAAACTTGAAAATGGAGATGAGGAAGCTCTCGCTCTTTGGCAATGGTTCCGCGATGAAAGTTTAGTGGAATTTAAC
CGCCTTTACAATGAATTGAAAGTTGAATTTGACAGCTATAACGGAGAAGCCTTCTACAATGATAAGATGGATGCAGTTGT
AGACATTCTTTCTGAAAAAGGACTACTTCTTGAATCAGAAGGTGCCCAAGTTGTGAATCTTGAGAAATATGGAATTGAAC
ATCCAGCCCTTATCAAGAAGTCTGATGGTGCAACTCTCTATATCACACGTGACTTGGCTGCAGCCCTTTACCGTAAAAAC
GAATACCAATTTGCTAAATCTATCTATGTCGTTGGTCAAGAACAATCTGCCCACTTTAAACAGCTCAAAGCTGTCTTGCA
AGAGATGGGCTACGACTGGAGTGACGACATTACTCACGTTCCTTTTGGCTTGGTTACAAAAGAAGGGAAGAAGCTCTCTA
CTCGTAAAGGGAATGTCATCTTGCTAGAGCCTACTGTTGCAGAGGCTGTTAGCCGTGCCAAGGTCCAAATCGAGGCTAAA
AATCCTGAATTGGAAAATAAAGATCAGGTAGCACATGCTGTTGGGGTTGGAGCCATTAAATTCTATGACCTCAAAACCGA
CCGTACAAATGGATACGACTTCGACCTAGAGGCTATGGTATCCTTCGAGGGTGAAACTGGACCTTACGTTCAATATGCCT
ACGCTCGTATCCAATCTATCTTACGCAAAGCCGATTTCAAACCAGAAACAGCTGGCAACTATAGCTTGAATGATACTGAA
AGCTGGGAAATCATTAAACTCATTCAAGACTTCCCACGTATTATCAACCGTGCGGCAGATAACTTTGAACCTTCTATCAT
TGCTAAATTTGCAATTAGCCTGGCTCAATCCTTTAACAAATACTATGCACATACACGTATCTTGGATGAAAGCCCAGAAC
GCGACAGCCGTCTAGCCCTCAGCTACGCAACCGCAGTCGTTCTCAAAGAAGCCCTTCGCTTGCTTGGAGTAGAAGCGCCA
GAGAAGATGTAA

Upstream 100 bases:

>100_bases
ATAACCATATTATACCAAAAAAACAGGAGATTTCAAAAATTTTTTCTTCTTTCTTTAAAATTGTGATAAAATAGTAGAAA
AGTCCAAAAAGGAGCTCTTA

Downstream 100 bases:

>100_bases
ATCGCCAAAGTTACTTGATTGCAAAGCAATCTAAGTAACTAACGCCAAATCCTATTCGGACTTTGGCTAGGTGCTTCACT
AGTCATGACCCCTAAATATA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVN
FFLDKSTISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKN
EYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAK
NPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAP
EKM

Sequences:

>Translated_563_residues
MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVN
FFLDKSTISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKN
EYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAK
NPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAP
EKM
>Mature_563_residues
MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVN
FFLDKSTISAQVLQAVTTEKEHYADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKN
EYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAK
NPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAP
EKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI197100773, Length=584, Percent_Identity=33.7328767123288, Blast_Score=328, Evalue=6e-90,
Organism=Homo sapiens, GI15149476, Length=556, Percent_Identity=29.3165467625899, Blast_Score=237, Evalue=2e-62,
Organism=Escherichia coli, GI1788184, Length=538, Percent_Identity=34.0148698884758, Blast_Score=289, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI71985061, Length=574, Percent_Identity=31.184668989547, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI71985068, Length=551, Percent_Identity=31.0344827586207, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17532153, Length=497, Percent_Identity=27.1629778672032, Blast_Score=176, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6320548, Length=578, Percent_Identity=35.9861591695502, Blast_Score=377, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321883, Length=568, Percent_Identity=34.1549295774648, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI18859963, Length=545, Percent_Identity=31.3761467889908, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI28571570, Length=469, Percent_Identity=31.7697228144989, Blast_Score=224, Evalue=1e-58,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63473; Mature: 63473

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAEL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
AEKMNSQAFEKVVATGPYVNFFLDKSTISAQVLQAVTTEKEHYADQNIGKQENVVIDMSS
HHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
PNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGDWGKQFGMLIVAYKKWGDEEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCEEEEEEECCCCCCC
VKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
CCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKK
HHHHHHEEEEECCCCCEEECCHHHHHHHHHHCCCCEEECCCCCEEEHHHHCCCCCCEEEE
SDGATLYITRDLAAALYRKNEYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHV
CCCCEEEEEHHHHHHHHHCCHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
PFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAKNPELENKDQVAHAVGVGAIK
CCCEEECCCCEEECCCCCEEEECCHHHHHHHHCEEEEEECCCCCCCHHHHHHHHCCCEEE
FYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLAL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYATAVVLKEALRLLGVEAPEKM
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFSLAKVERKAPQMIAAEL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
AEKMNSQAFEKVVATGPYVNFFLDKSTISAQVLQAVTTEKEHYADQNIGKQENVVIDMSS
HHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
PNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGDWGKQFGMLIVAYKKWGDEEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCEEEEEEECCCCCCC
VKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLENGDEEALALWQWFRDESLVEFN
CCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHH
RLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLLLESEGAQVVNLEKYGIEHPALIKK
HHHHHHEEEEECCCCCEEECCHHHHHHHHHHCCCCEEECCCCCEEEHHHHCCCCCCEEEE
SDGATLYITRDLAAALYRKNEYQFAKSIYVVGQEQSAHFKQLKAVLQEMGYDWSDDITHV
CCCCEEEEEHHHHHHHHHCCHHHHHHEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCC
PFGLVTKEGKKLSTRKGNVILLEPTVAEAVSRAKVQIEAKNPELENKDQVAHAVGVGAIK
CCCEEECCCCEEECCCCCEEEECCHHHHHHHHCEEEEEECCCCCCCHHHHHHHHCCCEEE
FYDLKTDRTNGYDFDLEAMVSFEGETGPYVQYAYARIQSILRKADFKPETAGNYSLNDTE
EEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SWEIIKLIQDFPRIINRAADNFEPSIIAKFAISLAQSFNKYYAHTRILDESPERDSRLAL
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYATAVVLKEALRLLGVEAPEKM
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA