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The map label for this gene is ftsK [H]

Identifier: 169833549

GI number: 169833549

Start: 904299

End: 906524

Strand: Direct

Name: ftsK [H]

Synonym: SPH_0983

Alternate gene names: 169833549

Gene position: 904299-906524 (Clockwise)

Preceding gene: 169834156

Following gene: 169833424

Centisome position: 40.27

GC content: 43.62

Gene sequence:

>2226_bases
ATGTTGATTTCATTAGGAATTGCGATTTTATTGATTTTCGCAGCCTTCAAATTAGGGGCTGCAGGTATAACCCTTTATAA
TTTAATTCGCTTGCTAGTGGGTAGCCTAGCTTATCTGGCGATATTCGGCCTATTAATCTATCTCTTCTTTTTCAAGTGGA
TACGAAAACAGGAAGGACTCTTATCTGGCTTTTTCACCATATTTGCTGGCTTACTCTTGATTTTTGAGGCCTACTTAGTT
TGGAAATATGGTTTGGACAAGTCCGTTCTAAAAGGGACCATGGCTCAGGTTGTGACAGATCTGACTGGTTTTCGAACGAC
TAGCTTTGCTGGAGGGGGCTTGATCGGGGTCGCTCTTTATATTCCAACAGCCTTTCTCTTTTCAAATATCGGAACTTACT
TTATTGGTTCTATCTTGATTTTAGTGGGTTCTCTCCTAGTCAGCCCTTGGTCTGTTTACGATATTGCTGAATTTTTCAGT
AGAGGCTTTGCCAAATGGTGGGAAGGGCACGAGCGTCGAAAAGAGGAACGCTTTGTCAAACAAGAAGAAAAAGCTCGCCA
AAAGGCTGAGAAAGAGGCTAGATTAGAACAAGAAGAGACTGAAAAAGCCTTACTCGATTTGCCTCCTGTTGATATGGAAA
CGGGTGAAATTCTGACAGAGGAAGCTGTTCAAAATCTTCCACCTATTCCAGAAGAAAAGTGGGTGGAACCAGAAATCATC
CTGCCTCAAGCTGAACTTAAATTCCCTGAACAGGAAGATGACTCAGATGACCAAGATGTTCAGGTCGATTTTTCAGCCAA
AGAAGCCCTTGAATACAAACTTCCAAGCTTACAACTCTTTGCACCAGATAAACCAAAAGATCAGTCTAAAGAGAAGAAAA
TTGTCAGAGAAAATATCAAAATCTTAGAAGCAACCTTTGCTAGCTTTGGTATTAAGGTAACAGTTGAACGGGCCGAAATT
GGGCCATCAGTGACCAAGTATGAAGTCAAGCCGGCTGTTGGTGTAAGGGTCAACCGCATTTCCAATCTATCAGATGACCT
CGCTCTAGCCTTGGCTGCCAAAGATGTCCGGATTGAAGCACCAATCCCTGGGAAATCCCTAATCGGAATTGAAGTGCCCA
ACTCCGATATTGCCACTGTATCTTTCCGAGAACTATGGGAACAATCGCAAACGAAAGCAGAAAATTTCTTGGAAATTCCT
TTAGGGAAGGCTGTTAATGGAACCGCAAGAGCTTTTGACCTTTCTAAAATGCCCCACTTGCTAGTTGCAGGTTCAACGGG
TTCAGGGAAGTCAGTAGCAGTTAACGGCATTATTGCTAGCATTCTCATGAAGGCGAGACCAGATCAAGTTAAATTTATGA
TGGTCGATCCCAAGATGGTTGAGTTATCTGTTTACAATGATATTCCCCACCTCTTGATTCCAGTCGTGACCAATCCACGT
AAAGCCAGCAAGGCTCTGCAAAAGGTTGTGGATGAAATGGAAAACCGTTATGAACTCTTTGCCAAGGTGGGAGTTCGGAA
TATTGCAGGTTTTAATGCCAAGGTAGAAGAGTTCAATTCCCAGTCTGAGTACAAGCAAATTCCGCTACCATTCATTGTCG
TGATTGTGGATGAGTTGGCTGACCTCATGATGGTGGCCAGCAAGGAAGTGGAAGATGCTATCATCCGTCTTGGGCAGAAG
GCGCGTGCTGCAGGTATCCACATGATTCTTGCAACTCAGCGTCCATCTGTTGATGTCATCTCTGGTTTGATTAAGGCCAA
TGTTCCATCTCGTGTAGCATTTGCGGTTTCATCAGGAACAGACTCCCGTACGATTTTGGATGAAAATGGAGCAGAAAAAC
TTCTTGGTCGAGGAGACATGCTCTTTAAACCGATTGATGAAAATCATCCAGTTCGTCTCCAAGGCTCCTTTATCTCGGAT
GACGATGTTGAGCGCATTGTGAACTTCATCAAGACTCAGGCAGATGCAGACTACGATGAGAGTTTTGATCCAGGTGAGGT
TTCTGAAAATGAAGGAGAATTTTCGGATGGAGATGCTGGTGGTGATCCGCTTTTTGAAGAAGCTAAGTCTTTGGTTATCG
AAACACAGAAAGCCAGTGCATCCATGATTCAGCGTCGTTTGTCAGTTGGATTTAACCGTGCGACCCGTCTCATGGAAGAG
CTTGAGATGGCAGGTGTCATTGGTCCAGCTGAAGGTACCAAACCAAGAAAAGTTTTACAACAATAA

Upstream 100 bases:

>100_bases
TGAAATATGGTATAATAGAAGAATGGCAAACAAGAATACAAGTACAACAAGACGGAGACCGTCTAAAGCAGAACTGGAAA
GAAAAGAAGCGATTCAACGA

Downstream 100 bases:

>100_bases
AAAAATAGCTTCTTTCCAAGTTTGGAAGGAGGCTATTTTAGTGATTATTGATTAGTTTTATTTTCCGAAGTTGGGGTATT
GGACTGTTTTTCGTTTTCAG

Product: DNA translocase FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 741; Mature: 741

Protein sequence:

>741_residues
MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLV
WKYGLDKSVLKGTMAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEILTEEAVQNLPPIPEEKWVEPEII
LPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEI
GPSVTKYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTKAENFLEIP
LGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPR
KASKALQKVVDEMENRYELFAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQK
ARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISD
DDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEE
LEMAGVIGPAEGTKPRKVLQQ

Sequences:

>Translated_741_residues
MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLV
WKYGLDKSVLKGTMAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEILTEEAVQNLPPIPEEKWVEPEII
LPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEI
GPSVTKYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTKAENFLEIP
LGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPR
KASKALQKVVDEMENRYELFAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQK
ARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISD
DDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEE
LEMAGVIGPAEGTKPRKVLQQ
>Mature_741_residues
MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLV
WKYGLDKSVLKGTMAQVVTDLTGFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEILTEEAVQNLPPIPEEKWVEPEII
LPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPSLQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEI
GPSVTKYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTKAENFLEIP
LGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPR
KASKALQKVVDEMENRYELFAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQK
ARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISD
DDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEE
LEMAGVIGPAEGTKPRKVLQQ

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=491, Percent_Identity=46.2321792260692, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 81929; Mature: 81929

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFKWIRKQEGL
CEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLTGFRTTSFAGGGLIGVALY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFSRGFAKWWEGHERRKEERFVK
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEILTEEAVQNLPPIPEEKWVEPEII
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEE
LPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPSLQLFAPDKPKDQSKEKKIVRENIK
CCHHHCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHH
ILEATFASFGIKVTVERAEIGPSVTKYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEA
HHHHHHHHCCEEEEEEHHHCCCCCEEEEECCCCCEEHHHHCCCCHHHHHHEEECCEEEEC
PIPGKSLIGIEVPNSDIATVSFRELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHL
CCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHEEECCCCCCE
LVAGSTGSGKSVAVNGIIASILMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPR
EEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECCCCCH
KASKALQKVVDEMENRYELFAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCCHHHHHHHHHHH
DLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGT
HHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCC
DSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDE
CCCEEECCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
SFDPGEVSENEGEFSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LEMAGVIGPAEGTKPRKVLQQ
HHHHCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGLLIYLFFFKWIRKQEGL
CEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLTGFRTTSFAGGGLIGVALY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
IPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFSRGFAKWWEGHERRKEERFVK
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEILTEEAVQNLPPIPEEKWVEPEII
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEE
LPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPSLQLFAPDKPKDQSKEKKIVRENIK
CCHHHCCCCCCCCCCCCCCEEEECCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHH
ILEATFASFGIKVTVERAEIGPSVTKYEVKPAVGVRVNRISNLSDDLALALAAKDVRIEA
HHHHHHHHCCEEEEEEHHHCCCCCEEEEECCCCCEEHHHHCCCCHHHHHHEEECCEEEEC
PIPGKSLIGIEVPNSDIATVSFRELWEQSQTKAENFLEIPLGKAVNGTARAFDLSKMPHL
CCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHEEECCCCCCE
LVAGSTGSGKSVAVNGIIASILMKARPDQVKFMMVDPKMVELSVYNDIPHLLIPVVTNPR
EEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEECCEEEEEEECCCCCCCEEECCCCCH
KASKALQKVVDEMENRYELFAKVGVRNIAGFNAKVEEFNSQSEYKQIPLPFIVVIVDELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCCHHHHHHHHHHH
DLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRVAFAVSSGT
HHHHHHHHHHHHHHHHHCCHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCC
DSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKTQADADYDE
CCCEEECCCCHHHHHCCCCCEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
SFDPGEVSENEGEFSDGDAGGDPLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LEMAGVIGPAEGTKPRKVLQQ
HHHHCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]