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The map label for this gene is iga [H]

Identifier: 169833458

GI number: 169833458

Start: 1133305

End: 1138983

Strand: Direct

Name: iga [H]

Synonym: SPH_1229

Alternate gene names: 169833458

Gene position: 1133305-1138983 (Clockwise)

Preceding gene: 169833913

Following gene: 169832549

Centisome position: 50.47

GC content: 36.15

Gene sequence:

>5679_bases
ATGGAAAAGTATTTTGGTGAAAAACAAGAGCGTTTTTCATTTAGAAAATTATCAGTAGGACTTGTATCTGCAACGATTTC
AAGTTTATTTTTTATGTCTGTATTAGCTAGTTCATCTGTGGATGCTCAAGAAACTGCGGGAGTTCACTATAAATATGTGG
CAGATTCAGAGCTATCATCAGAAGAAAAGAAGCAGCTTGTCTATGATATTCCGACATACGTGGAGAATGATGATGAAACT
TATTATCTTGTTTATAAGTTAAATTCTCAAAATCAACTGGCGGAATTACCAAATACTGGAAGCAAGAATGAGAGGCAAGC
CCTAGTTGCTGGTGCTAGCTTAGCTGCTCTGGGAATTTTAATTTTTGCTGTTTCCAAGAAAAAGGTTAAGAATAAAACGG
TATTACATTTAGTATTGGTTGCGGGAATAGGAAATGGTGTCTTAGTTTCAGTCCATGCTTTAGAAAATCATCTTTTGCTA
AATTACAATACGGACTATGAATTGACCTCTGGAGAAAAATTACCTCTTCCTAAAGAGATTTCAGGTTACACTTATATTGG
ATATATCAAAGAGGGAAAAACGACTTCTGATTTTGAAGTAAGTAATCAAGAAAAATCAGCAGCCACTCCTACAAAACAAC
AAAAGGTGGATTATAATGTTACACCAAATTTTGTAGACCATCCATCAACAGTACAAGCTATTCAGGAACAAACACCTGTT
TCTTCAACTAAGCCGACAGAAGTTCAAGTAGTTGAAAAACCTTTCTCTACTGAATTAATCAATCCAAGAAAAGAAGAGAA
ACAATCTTCAGATTCTCAAGAACAATTAGCCGAACATAAGAATCTAGAAACGAAGAAAGAGGAGAAGATTTCTCCAAAAG
AAAAGACTGGGGTAAATACATTAAATCCACAGGATGAAGTTTTATCAGGTCAATTGAACAAACCTGAACTCTTATATCGT
GAGGAAACTATAGAGATAAAAATAGATTTTCAAGAAGAAATTCAAGAAAATCCTGATTTAGTTGAAGGAATTGTAAGAGT
AAAACAAGAAGGTAAATTAGGTAAGAAAGTTGAAATCGTCAGAATATTCTCTGTAAACAAGGAAGAAGTTTCGCGAGAAA
TTGTTTCAACTTCAACGACTGCGCCTATTCCAAGAATAGTCGAAAAAGGTACTAAAAAAACTCAAGTTATAAAGGAACAA
CCTGAGACTGGTGTAGAACATAAGGACGTACAGTCTGGAGCTATTGTTGAACCCGCAATTCAGCCTGAGTTGCCCGAAGC
TGTAGTAAGTGACAAAGGCGTACCAGAAGTTCAACCAGCGTTGTCCAAAGCAGTTATAACCGACAAAGGTGAGACTGAGG
TTCAACCAGAGTCGCCAGATACTGTGGTAAGTGATAAAGGTGAACCAGCAGTCCAACCAGAGTCGCCAGATACTGTGGTA
AGTGATAAAGGTGAACCTAAACAGGTAGCACCGCTTCCAGAATATACAGGACCACAAGCCAGCGCTATTGTTGAACCAGA
GCAGGTAGCACCACTACCAGAATACACAGGGGTACAAGCCGGAGCTATTGTTGAACCCGCAGTCCAGCCAGCGTTACCCG
AAGCAGTTGTAAGCGATAAAGGCGTACCAGAAGTTCAGCCTGAGTTGCCCGAAGCAGTAGTAAGTGATAAAGGCGTACCA
GAAGTTCAGCCTGAATTACCCGAAGCAGTTGTAAGTGATAAAGGTGAACCAGAGCAGGTAGCACCATTGCCAGAATATAA
GGGGAATATTGAGCAAGTAAAACCTGAAACTCCGGTTGAGAAACTTCAAGAGGAAGAACCAGAGAAAACAATAGAACTAA
GAAGTGTTTCTGATGTGGAACTCTATAGTTATGAAGCTAATCAATCAAAACAACATACAATCTTAGATAAAGTACCAGAT
AATAAATCTGCTTATTTCATCAAAGTGAAGTCAGCTAAATTTAAAGATGTACTGCTCCCAGTTTCAAACATTGAGGACAC
TACAAAAGACGGTAAAGTAGTCTATAAAATTACAGCTAGATTGGAACACTTAAAACAATCTGTAGACAATCAATACCAAG
ATAATTTTACTTATTATCTTCCAAAAGTTGTTCAAAACGATGGCCCTATCTACACATCATTTAAAAAATTAGTAACTGAT
ATGAATAGTAGACCTGATGGAACATTTATACTTGGCGCGACCATGAATGCTCGTGAGTTTGAGTTGGGTGAAAATCAAGA
AAGTTATGTTACAAAGAATTTCACAGGGACATTAATTGGTAGTCATCAAGGTAAACATTATGCTATCTATAATTTGAAAA
AGCCATTATTCAATACATTAAATAATGCTGCTATTCAGGATCTCACCTTGAAAGATGTCAATATTTCTGGTAAGAATCAT
GTCGCATCAGTTGCTATGGAAGCCACAAATTCTTCAACTTTAGATAACGTTCACGCAAATGGAATCATTGCTGGTGAACT
AGGTATCGGAGGACTTGTCCAAAAAGTTGATAATTCTACAGTAAGAAATAGTAGCTTCACCGGAAGAATAACAAATACTT
TTGTTACAACTTCTCAGTATGCAATTGGTGGTCTAGTCGGTCAATTAACCGGTGCTAATGCTAGGGTAGCTCATTCTATT
TCAACAGTAGTCATTTCAAGTAATGGAGAACATTCTAATCAAACAATTGGTGGTATTGTTGGTATTGTAGAAAATAATGC
GACTGTAGAAAATAGTTATGCTGAAGGTGAAATAAATAATGCTAAACCATTCGCTAGAGTTGGTGGAGTTGCAGGTTCCC
TATGGACACAAGAAGGCGGAACAGATAACAATACTGGTCGCTTGACAAATGTTCTCAGCGATATGAATATTACAAATGGG
AATGCGATTTCTGGTTACCACTTCAATGGTATAAAGGAAACAAATGTCTATAGTAATAAAGAAAACAAAGTAGTCAACGT
TCAAGCAGTTGGAGATGAGGTAATGTCAGTTGATTCCACTGTAGAACGTGGTACTGAGATTGAAAAAACATCAGTTCAAG
CTAAGAAAGATGAGATTACTAAAAAACACACTATCACAGTGGAAGATTTCACAAATTCTGTTAAACAGGATGTAGATTAT
ACCAAGGCAGCACATTATCAATCAACAAGAGAAGTTGCATATAAAAATATAGAAAAATTATTACCTTTCTATAATAGAGA
TACTATTGTGAAATATGGAAATCAATTATCTACTGATCATAACCTGTTTAAGAAAGAATTGTTGTCTGTTGTAGCTATGA
AAAATGATGAAGTAGTCTCAGATATCACTTCAAACAAGAACTCTATCAATCACTTACTACTACATTACAAAGACGGAACA
TCTGAGAAAGTAGATTTAACCTACAATAGTGACTTTGCAAATCTGGCTGAGTATAATATTGAAAATACTGGTCTAGTATA
CACACCAAATGCTTTCCTAAAAAATTATACGCCTATAATAGACAGAGTTAAAAATGATTTAACTGCAGTACCGTATAATC
CAACTGCTCTTAAGAATTTGTTAGGAATCTCTGATAATGTTAAATTAACAGAACTTTATCTAGATGAGCAATTCACTAAG
ACCAAAGAGCACTTAACTGAAACTCTTAAAAAATTACTTTCAGCTGATGCTGCTGTTTCTGGAAATAATGATATAATTGA
CAATTACATTGTTGATAAAATCAAGCGAAACAAAGAAGCCTTGATGCTAGGATTAACCTATCTAGAACGCTGGTATGATT
TCAAATTCGATAAGGCTAGCGCAAAAGATTTGCTTATGTTCCATATGGATTTCTTTGGTAAGGGAAATACCTCTCCGCTA
GATGCAATTATCGAATTAGGTAAATCTGGCTACAACAATCTCTTGGCCAAAAATAATGTGGTTACTTACAATGCCTTGTT
AACGAATAACTACGGTACAAAAGATCTGTTTAGTGCTTTAGAAGGCTACCGTAAAGCATTTGCACCGCATCAAACTAACA
ATGAATGGTTTAAATCACAGACTAAGGCTTACATTGTCGAAGAAAAATCCAATATCGAAGAGGTGAAAACGAAGCAAGGA
CTAGTTGGCACTAAGTATTCTATTGGTGTCTATGACCGTATCACTAGTGCCACATGGAAATACCGCAATATGGTCTTGCC
GCTCCTAACCTTGCCGGAGAAATCAGTCTTTGTCATCTCGACCATCTCTAGTCTAGGATTTGGAGCTTATGATCGTTACC
GCAATAGTGAGCACAAAGCAGGCAAGGACCTCAATGATTTTGTTGAAGAAAATGCACGTGAAACAGCCAAACATCAGCGA
GATCACTACGATTATTGGTATCGTATTTTAGACGACAATGCACGTGAAAAACTTTATAGAAATATTTTGCTTTACGATGC
TTATAAATTTGGCGATGATAATACCGTAGGGAAAGCTACAGAAGTGGCAGATTTTGATAATCCAAATCCTGCAATGCAAC
ATTTCTTTGGACCTGTTGGAAATAAAGTTGGGCATAATCAACACGGTGCTTATGCTACAGGTGATGCAGTTTATTATATG
GGTTATCGAATGTTGGATAAGGATGGAGCTATTACTTATACGCATGAGATGACACATGACTCAGATCAGGACATTTATCT
TGGAGGATATGGTCGAAGAAGTGGCTTGGGACCAGAGTTCTTTGCTAAAGGATTATTACAAGCACCAGACCATCCAGATG
ATGCGACCATTACCATCAACTCCATCTTGAAACATTCGAAATCTGATAGTACAGAAAGTCGACGATTACAAGTACTTGAT
CCAACTACAAGATTTAATAATGCAGATGATTTGAAGCAATATGTCCACAACATGTTTGACGTTGTTTATATGTTGGAATA
TCTCGAAGGAAATTCAATTCTTAAATTGGATACGAATCAAAAACAACAACTTCTTAGAAAAGTTACAAATGAGTACCATC
CTGATCCTGATGGAAATAAGGTCTATGCAACAAATGTTGTCAGAAATATAACAGTAGAAGAAGTTGAAAGACTACGTTCA
TTCAATGATTTGATTGATAATAATATTCTTTCGTCTAGGGAATATGCCTCAGGTAAATACGAAAGAAATGGCTATTTCAC
TATTAAATTATTTGCGCCGATTTATGCAGCATTAAGTAATGATGACGGAACGCCAGGTGATCTGATGGGACGTCGTATGG
CCTATGAACTATTAGCTGCAAAAGGCTTTAAAGATGGTATGGTGCCATATATCTCAAATCAATTTGAAGCAGATGCTAGG
GCAAATAATAAAACGATTACCTCATATGGTAAGACCAAAGGATTAGTAACAGATACATTAGTTCTTCAAAGATTATTTAA
TGGACAATACAATACCTGGAGTGATTTTAAGAAAGCTATGTATAAAGAACGTCAGGATAAATTCAATAAATTGAACAAAA
TTTCATTTAAAGATCCGTCTCAACCTTGGACGCGCAATATTATTAAGACAATTCACAGTGTAAATGAACTGCAGAACTTA
ATGAATGAAGCTGTCCGCAAGGATACAGAAACTCCTCATTGGTATAACTATAATCCAGAAATAGACAGTGCAGTTCATAA
GTTGAAGAGAGCAATCTTTAAAGCCTATCTTGACCAAACAAATGATTTTAGAAGTTCAATTTTTGAGAATAAAAAATAG

Upstream 100 bases:

>100_bases
GTATAATTAAGGTATACTGCCTTTTCTATAGATAATAGATAATACACTAATATAATAAAGGTCTTTGTAACATATATAAA
TTTTATTTCAAGGAGGAATA

Downstream 100 bases:

>100_bases
TGTTTACTATTAGGAAATAAAGTTTAAAAAGGTGATGAAGAACAAACCAAGATTCAAGCAGGAATTCCTACTGATAATGA
AGTAAGTTATGCTCTTATTT

Product: immunoglobulin A1 protease

Products: NA

Alternate protein names: IgA1 protease; IgA-specific zinc metalloproteinase [H]

Number of amino acids: Translated: 1892; Mature: 1892

Protein sequence:

>1892_residues
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDET
YYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYR
EETIEIKIDFQEEIQENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIKEQ
PETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPAVQPESPDTVV
SDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVEPAVQPALPEAVVSDKGVPEVQPELPEAVVSDKGVP
EVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKLQEEEPEKTIELRSVSDVELYSYEANQSKQHTILDKVPD
NKSAYFIKVKSAKFKDVLLPVSNIEDTTKDGKVVYKITARLEHLKQSVDNQYQDNFTYYLPKVVQNDGPIYTSFKKLVTD
MNSRPDGTFILGATMNAREFELGENQESYVTKNFTGTLIGSHQGKHYAIYNLKKPLFNTLNNAAIQDLTLKDVNISGKNH
VASVAMEATNSSTLDNVHANGIIAGELGIGGLVQKVDNSTVRNSSFTGRITNTFVTTSQYAIGGLVGQLTGANARVAHSI
STVVISSNGEHSNQTIGGIVGIVENNATVENSYAEGEINNAKPFARVGGVAGSLWTQEGGTDNNTGRLTNVLSDMNITNG
NAISGYHFNGIKETNVYSNKENKVVNVQAVGDEVMSVDSTVERGTEIEKTSVQAKKDEITKKHTITVEDFTNSVKQDVDY
TKAAHYQSTREVAYKNIEKLLPFYNRDTIVKYGNQLSTDHNLFKKELLSVVAMKNDEVVSDITSNKNSINHLLLHYKDGT
SEKVDLTYNSDFANLAEYNIENTGLVYTPNAFLKNYTPIIDRVKNDLTAVPYNPTALKNLLGISDNVKLTELYLDEQFTK
TKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLTYLERWYDFKFDKASAKDLLMFHMDFFGKGNTSPL
DAIIELGKSGYNNLLAKNNVVTYNALLTNNYGTKDLFSALEGYRKAFAPHQTNNEWFKSQTKAYIVEEKSNIEEVKTKQG
LVGTKYSIGVYDRITSATWKYRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNSEHKAGKDLNDFVEENARETAKHQR
DHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAYATGDAVYYM
GYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLD
PTTRFNNADDLKQYVHNMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNITVEEVERLRS
FNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDDGTPGDLMGRRMAYELLAAKGFKDGMVPYISNQFEADAR
ANNKTITSYGKTKGLVTDTLVLQRLFNGQYNTWSDFKKAMYKERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNL
MNEAVRKDTETPHWYNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK

Sequences:

>Translated_1892_residues
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDET
YYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYR
EETIEIKIDFQEEIQENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIKEQ
PETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPAVQPESPDTVV
SDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVEPAVQPALPEAVVSDKGVPEVQPELPEAVVSDKGVP
EVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKLQEEEPEKTIELRSVSDVELYSYEANQSKQHTILDKVPD
NKSAYFIKVKSAKFKDVLLPVSNIEDTTKDGKVVYKITARLEHLKQSVDNQYQDNFTYYLPKVVQNDGPIYTSFKKLVTD
MNSRPDGTFILGATMNAREFELGENQESYVTKNFTGTLIGSHQGKHYAIYNLKKPLFNTLNNAAIQDLTLKDVNISGKNH
VASVAMEATNSSTLDNVHANGIIAGELGIGGLVQKVDNSTVRNSSFTGRITNTFVTTSQYAIGGLVGQLTGANARVAHSI
STVVISSNGEHSNQTIGGIVGIVENNATVENSYAEGEINNAKPFARVGGVAGSLWTQEGGTDNNTGRLTNVLSDMNITNG
NAISGYHFNGIKETNVYSNKENKVVNVQAVGDEVMSVDSTVERGTEIEKTSVQAKKDEITKKHTITVEDFTNSVKQDVDY
TKAAHYQSTREVAYKNIEKLLPFYNRDTIVKYGNQLSTDHNLFKKELLSVVAMKNDEVVSDITSNKNSINHLLLHYKDGT
SEKVDLTYNSDFANLAEYNIENTGLVYTPNAFLKNYTPIIDRVKNDLTAVPYNPTALKNLLGISDNVKLTELYLDEQFTK
TKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLTYLERWYDFKFDKASAKDLLMFHMDFFGKGNTSPL
DAIIELGKSGYNNLLAKNNVVTYNALLTNNYGTKDLFSALEGYRKAFAPHQTNNEWFKSQTKAYIVEEKSNIEEVKTKQG
LVGTKYSIGVYDRITSATWKYRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNSEHKAGKDLNDFVEENARETAKHQR
DHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAYATGDAVYYM
GYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLD
PTTRFNNADDLKQYVHNMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNITVEEVERLRS
FNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDDGTPGDLMGRRMAYELLAAKGFKDGMVPYISNQFEADAR
ANNKTITSYGKTKGLVTDTLVLQRLFNGQYNTWSDFKKAMYKERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNL
MNEAVRKDTETPHWYNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK
>Mature_1892_residues
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDET
YYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYR
EETIEIKIDFQEEIQENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIKEQ
PETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPAVQPESPDTVV
SDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVEPAVQPALPEAVVSDKGVPEVQPELPEAVVSDKGVP
EVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKLQEEEPEKTIELRSVSDVELYSYEANQSKQHTILDKVPD
NKSAYFIKVKSAKFKDVLLPVSNIEDTTKDGKVVYKITARLEHLKQSVDNQYQDNFTYYLPKVVQNDGPIYTSFKKLVTD
MNSRPDGTFILGATMNAREFELGENQESYVTKNFTGTLIGSHQGKHYAIYNLKKPLFNTLNNAAIQDLTLKDVNISGKNH
VASVAMEATNSSTLDNVHANGIIAGELGIGGLVQKVDNSTVRNSSFTGRITNTFVTTSQYAIGGLVGQLTGANARVAHSI
STVVISSNGEHSNQTIGGIVGIVENNATVENSYAEGEINNAKPFARVGGVAGSLWTQEGGTDNNTGRLTNVLSDMNITNG
NAISGYHFNGIKETNVYSNKENKVVNVQAVGDEVMSVDSTVERGTEIEKTSVQAKKDEITKKHTITVEDFTNSVKQDVDY
TKAAHYQSTREVAYKNIEKLLPFYNRDTIVKYGNQLSTDHNLFKKELLSVVAMKNDEVVSDITSNKNSINHLLLHYKDGT
SEKVDLTYNSDFANLAEYNIENTGLVYTPNAFLKNYTPIIDRVKNDLTAVPYNPTALKNLLGISDNVKLTELYLDEQFTK
TKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLTYLERWYDFKFDKASAKDLLMFHMDFFGKGNTSPL
DAIIELGKSGYNNLLAKNNVVTYNALLTNNYGTKDLFSALEGYRKAFAPHQTNNEWFKSQTKAYIVEEKSNIEEVKTKQG
LVGTKYSIGVYDRITSATWKYRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNSEHKAGKDLNDFVEENARETAKHQR
DHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAYATGDAVYYM
GYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLD
PTTRFNNADDLKQYVHNMFDVVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNITVEEVERLRS
FNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDDGTPGDLMGRRMAYELLAAKGFKDGMVPYISNQFEADAR
ANNKTITSYGKTKGLVTDTLVLQRLFNGQYNTWSDFKKAMYKERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNL
MNEAVRKDTETPHWYNYNPEIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK

Specific function: Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region, rendering it less efficient in coating the surface of colonizing or invading pneumococci. Strongly contributes to virulence in mice. May be responsible for pneumococc

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall. Membrane; Multi-pass membrane protein (By similarity). Secreted, cell wall; Peptidoglycan-anchor (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G5 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011098
- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR019931
- InterPro:   IPR008006
- InterPro:   IPR011505
- InterPro:   IPR001899 [H]

Pfam domain/function: PF07501 G5; PF00746 Gram_pos_anchor; PF07580 Peptidase_M26_C; PF05342 Peptidase_M26_N; PF04650 YSIRK_signal [H]

EC number: =3.4.24.13 [H]

Molecular weight: Translated: 211435; Mature: 211435

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50847 GRAM_POS_ANCHORING ; PS51109 G5 ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCC
EEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGIL
HHHHHEEEECCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEI
HHHHHHHHHCCHHHEEEEEECCCCCCEEEEEEECCCEEEEEECCCEEECCCCCCCCCCCC
SGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNT
CCCCCCEEEEECCCCCCHHCCCCHHHHHCCCHHHHHHHHCCCCCCHHHCCCCHHHCCCCC
LNPQDEVLSGQLNKPELLYREETIEIKIDFQEEIQENPDLVEGIVRVKQEGKLGKKVEIV
CCCHHHHHCCCCCCCCEEEEEEEEEEEEEEHHHHCCCHHHHHHHHHHHHCCCCCCEEEEE
RIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAI
EEEECCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCC
QPELPEAVVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPAVQPESPDTVV
CCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEE
SDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVEPAVQPALPEAVVSDK
CCCCCCCCCCCCCCCCCCCCCEEECHHHCCCCCCCCCCCCCCEECCCCCCCCCHHHHCCC
GVPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVE
CCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHCCCHHHCCCCCCHH
KLQEEEPEKTIELRSVSDVELYSYEANQSKQHTILDKVPDNKSAYFIKVKSAKFKDVLLP
HHHHCCCCCEEEECCCCCEEEEEECCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCEEEE
VSNIEDTTKDGKVVYKITARLEHLKQSVDNQYQDNFTYYLPKVVQNDGPIYTSFKKLVTD
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCHHHHHHHHHHH
MNSRPDGTFILGATMNAREFELGENQESYVTKNFTGTLIGSHQGKHYAIYNLKKPLFNTL
CCCCCCCCEEEEECCCCCEECCCCCCCCEEECCCCEEEEECCCCCEEEEEECCHHHHHHH
NNAAIQDLTLKDVNISGKNHVASVAMEATNSSTLDNVHANGIIAGELGIGGLVQKVDNST
HHHHHCCEEEEEECCCCCCHHHHHEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHCCCC
VRNSSFTGRITNTFVTTSQYAIGGLVGQLTGANARVAHSISTVVISSNGEHSNQTIGGIV
CCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCEEE
GIVENNATVENSYAEGEINNAKPFARVGGVAGSLWTQEGGTDNNTGRLTNVLSDMNITNG
EEEECCCEECCCCCCCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
NAISGYHFNGIKETNVYSNKENKVVNVQAVGDEVMSVDSTVERGTEIEKTSVQAKKDEIT
CEECCEEECCEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
KKHTITVEDFTNSVKQDVDYTKAAHYQSTREVAYKNIEKLLPFYNRDTIVKYGNQLSTDH
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHH
NLFKKELLSVVAMKNDEVVSDITSNKNSINHLLLHYKDGTSEKVDLTYNSDFANLAEYNI
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCCHHHHHHCCC
ENTGLVYTPNAFLKNYTPIIDRVKNDLTAVPYNPTALKNLLGISDNVKLTELYLDEQFTK
CCCCEEECCCHHHHCCHHHHHHHHCCCEECCCCHHHHHHHHCCCCCCEEEEEEHHHHHHH
TKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLTYLERWYDFKFDKAS
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCC
AKDLLMFHMDFFGKGNTSPLDAIIELGKSGYNNLLAKNNVVTYNALLTNNYGTKDLFSAL
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHH
EGYRKAFAPHQTNNEWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWK
HHHHHHCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHCCCCCCEEECCHHHHHHHHHHH
YRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNSEHKAGKDLNDFVEENARETAKHQR
HHHEEEEEEECCCCCEEEEEEHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
DHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVG
CCHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
NKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEF
CCCCCCCCCCEECCCEEEEECEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCCHHH
FAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVHNMFD
HHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNITVEEVERLRS
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCHHHHHHHHH
FNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDDGTPGDLMGRRMAYELLAA
HHHHHHCCHHCCCHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
KGFKDGMVPYISNQFEADARANNKTITSYGKTKGLVTDTLVLQRLFNGQYNTWSDFKKAM
CCCCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
YKERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNLMNEAVRKDTETPHWYNYNPE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
IDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQETAGVHYKYVADSELSS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCCCCC
EEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSKNERQALVAGASLAALGIL
HHHHHEEEECCCCCCCCCCEEEEEEEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
IFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLLNYNTDYELTSGEKLPLPKEI
HHHHHHHHHCCHHHEEEEEECCCCCCEEEEEEECCCEEEEEECCCEEECCCCCCCCCCCC
SGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDYNVTPNFVDHPSTVQAIQEQTPV
CCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHCCC
SSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQLAEHKNLETKKEEKISPKEKTGVNT
CCCCCCEEEEECCCCCCHHCCCCHHHHHCCCHHHHHHHHCCCCCCHHHCCCCHHHCCCCC
LNPQDEVLSGQLNKPELLYREETIEIKIDFQEEIQENPDLVEGIVRVKQEGKLGKKVEIV
CCCHHHHHCCCCCCCCEEEEEEEEEEEEEEHHHHCCCHHHHHHHHHHHHCCCCCCEEEEE
RIFSVNKEEVSREIVSTSTTAPIPRIVEKGTKKTQVIKEQPETGVEHKDVQSGAIVEPAI
EEEECCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCC
QPELPEAVVSDKGVPEVQPALSKAVITDKGETEVQPESPDTVVSDKGEPAVQPESPDTVV
CCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEE
SDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVEPAVQPALPEAVVSDK
CCCCCCCCCCCCCCCCCCCCCEEECHHHCCCCCCCCCCCCCCEECCCCCCCCCHHHHCCC
GVPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVE
CCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHCCCHHHCCCCCCHH
KLQEEEPEKTIELRSVSDVELYSYEANQSKQHTILDKVPDNKSAYFIKVKSAKFKDVLLP
HHHHCCCCCEEEECCCCCEEEEEECCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCEEEE
VSNIEDTTKDGKVVYKITARLEHLKQSVDNQYQDNFTYYLPKVVQNDGPIYTSFKKLVTD
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCHHHHHHHHHHH
MNSRPDGTFILGATMNAREFELGENQESYVTKNFTGTLIGSHQGKHYAIYNLKKPLFNTL
CCCCCCCCEEEEECCCCCEECCCCCCCCEEECCCCEEEEECCCCCEEEEEECCHHHHHHH
NNAAIQDLTLKDVNISGKNHVASVAMEATNSSTLDNVHANGIIAGELGIGGLVQKVDNST
HHHHHCCEEEEEECCCCCCHHHHHEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHCCCC
VRNSSFTGRITNTFVTTSQYAIGGLVGQLTGANARVAHSISTVVISSNGEHSNQTIGGIV
CCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCCCCCCEEE
GIVENNATVENSYAEGEINNAKPFARVGGVAGSLWTQEGGTDNNTGRLTNVLSDMNITNG
EEEECCCEECCCCCCCCCCCCCCHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
NAISGYHFNGIKETNVYSNKENKVVNVQAVGDEVMSVDSTVERGTEIEKTSVQAKKDEIT
CEECCEEECCEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
KKHTITVEDFTNSVKQDVDYTKAAHYQSTREVAYKNIEKLLPFYNRDTIVKYGNQLSTDH
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHH
NLFKKELLSVVAMKNDEVVSDITSNKNSINHLLLHYKDGTSEKVDLTYNSDFANLAEYNI
HHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEEECCCCCEEEEEECCCHHHHHHCCC
ENTGLVYTPNAFLKNYTPIIDRVKNDLTAVPYNPTALKNLLGISDNVKLTELYLDEQFTK
CCCCEEECCCHHHHCCHHHHHHHHCCCEECCCCHHHHHHHHCCCCCCEEEEEEHHHHHHH
TKEHLTETLKKLLSADAAVSGNNDIIDNYIVDKIKRNKEALMLGLTYLERWYDFKFDKAS
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCC
AKDLLMFHMDFFGKGNTSPLDAIIELGKSGYNNLLAKNNVVTYNALLTNNYGTKDLFSAL
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHCCCCEEEEEEEEECCCCHHHHHHHH
EGYRKAFAPHQTNNEWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWK
HHHHHHCCCCCCCCHHHHCCCCEEEEECCCCHHHHHHHCCCCCCEEECCHHHHHHHHHHH
YRNMVLPLLTLPEKSVFVISTISSLGFGAYDRYRNSEHKAGKDLNDFVEENARETAKHQR
HHHEEEEEEECCCCCEEEEEEHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
DHYDYWYRILDDNAREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVG
CCHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
NKVGHNQHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEF
CCCCCCCCCCEECCCEEEEECEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCCHHH
FAKGLLQAPDHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVHNMFD
HHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
VVYMLEYLEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNITVEEVERLRS
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCHHHHHHHHH
FNDLIDNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDDGTPGDLMGRRMAYELLAA
HHHHHHCCHHCCCHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
KGFKDGMVPYISNQFEADARANNKTITSYGKTKGLVTDTLVLQRLFNGQYNTWSDFKKAM
CCCCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
YKERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNLMNEAVRKDTETPHWYNYNPE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCC
IDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]