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The map label for this gene is nrnA [H]

Identifier: 169833148

GI number: 169833148

Start: 1332582

End: 1333517

Strand: Direct

Name: nrnA [H]

Synonym: SPH_1440

Alternate gene names: 169833148

Gene position: 1332582-1333517 (Clockwise)

Preceding gene: 169834217

Following gene: 169834464

Centisome position: 59.34

GC content: 44.34

Gene sequence:

>936_bases
ATGGAGATTTGCCAACAAATTTTAGAAAAAATTAAAGAATACGACACCATTATCATTCATCGTCATATGAAACCAGACCC
TGATGCCTTGGGAAGTCAGGTGGGATTGAAAGCCTTGCTGGAACATCATTTCCCAGAAAAAACCATCAAAGCCGTCGGTT
TTGATGAACCAACTCTTACTTGGATGGCTGAGATGGATCTTGTTGAAGATAGAGCCTACCAAGGCGCACTTGTCATCGTC
TGTGATACAGCTAATACTGCTCGTATCGATGATAAGCGCTATAGTCAAGGTGATTTTCTCATTAAGATTGACCACCATCC
AAATGATGATGTATACGGTGACCTGTCTTGGGTCGATACTAGTTCAAGTAGCGCTAGCGAGATGATTACCCTATTTGCCC
AAACAACCCAACTAGCCTTGGCAGATCGCGATGCTGAGTTGCTCTTTGCAGGAATTGTCGGTGATACAGGTCGCTTCCTC
TACCCTTCTACCACTGCACGGACTCTTCGTCTGGCTGCTTATTTGAGAGAACATAACTTTGACTTTGCGGCTCTCACTCG
CAAAATGGACACTATGAGCTACAAAATTGCTAAACTGCAAGGCTACATCTACGACCATCTGGAAGTGGATGAAAATGGTG
CTGCTCGCGTTATCCTGAGTCAAGAAGTCTTGAAACAATACAATGTAACCGATGCTGAAACTGCAGCCATTGTCGGTGCA
CCTGGACGCATTGACAGAGTGAGTCTCTGGGGAATTTTTGTCGAACAGGCTGATGGCCACTACCGAGTTCGCTTACGCAG
TAAAGTCCATCCTATCAATGAAATTGCCAAGGAGCATGATGGTGGAGGCCACCCTCTAGCAAGTGGTGCTAATTCCTATA
GCCTAGAAGAAAACGAAATCATCTACCAAAAGTTAAAAAACTTGCTTAAAAACTGA

Upstream 100 bases:

>100_bases
GTCCTCCTCAATTTATCTTTCTCCATTATATCACATCTTTTTCATTTTAAAAATAAAAATTCTTGTGCTACAATGAAATG
AGAAAGAATTGAGGTTATTT

Downstream 100 bases:

>100_bases
TAAAATACTTGCCAAACTTTTCAGAATCTGATAGACTAGTATGGTAACAATCTATGGCTCGCAAAGAGACCATGGCAGAA
AGGAAATATTGCAAAATGAA

Product: DHH subfamily 1 protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHFPEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIV
CDTANTARIDDKRYSQGDFLIKIDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVILSQEVLKQYNVTDAETAAIVGA
PGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIAKEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN

Sequences:

>Translated_311_residues
MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHFPEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIV
CDTANTARIDDKRYSQGDFLIKIDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVILSQEVLKQYNVTDAETAAIVGA
PGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIAKEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN
>Mature_311_residues
MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHFPEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIV
CDTANTARIDDKRYSQGDFLIKIDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVILSQEVLKQYNVTDAETAAIVGA
PGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIAKEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34953; Mature: 34953

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHFPEKTIKAVGFDEPTLT
CHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEE
WMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIKIDHHPNDDVYGDLSWVDT
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEC
SSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFLYPSTTARTLRLAAYLREHNF
CCCCHHHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCEECCCCHHHHHHHHHHHHHCCC
DFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVILSQEVLKQYNVTDAETAAIVGA
CHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCEEEEEEHHHHHHCCCCCCCCEEEECC
PGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIAKEHDGGGHPLASGANSYSLEENEI
CCCCCEEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
IYQKLKNLLKN
HHHHHHHHHCC
>Mature Secondary Structure
MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHFPEKTIKAVGFDEPTLT
CHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEE
WMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIKIDHHPNDDVYGDLSWVDT
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEC
SSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFLYPSTTARTLRLAAYLREHNF
CCCCHHHHHHHHHHHHHEEEECCCCEEEEEEEECCCCCEECCCCHHHHHHHHHHHHHCCC
DFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVILSQEVLKQYNVTDAETAAIVGA
CHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCEEEEEEHHHHHHCCCCCCCCEEEECC
PGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIAKEHDGGGHPLASGANSYSLEENEI
CCCCCEEEEEEEEEEECCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
IYQKLKNLLKN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]