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The map label for this gene is insK [H]

Identifier: 169833138

GI number: 169833138

Start: 874516

End: 875349

Strand: Direct

Name: insK [H]

Synonym: SPH_0950

Alternate gene names: 169833138

Gene position: 874516-875349 (Clockwise)

Preceding gene: 169832899

Following gene: 169834087

Centisome position: 38.94

GC content: 36.93

Gene sequence:

>834_bases
ATGACTGAGTTTTCGTTAGTTCTTCTTCTAAAATCTATTAAACTAGCTCGTTGGACCTACTACTATCACTTGAAACAGCT
AGACAAAACAGATAAGGACCAAGAGCTTAAAGCTGAAATTCAATCCATCTTTATCGAACACAAAGGAAATTATGCTTATC
GCCGGGTTCATTTAGAACTAAGAAATCGTGCTTATCTGGTAAATCATAAAAGAGTTCAAGGCTTGATAAAAGTACTCAAT
TTACAAGCTAAAACGCGACAGAAACGAAAATATTCTTCTCATAAAGGAGACGTTGGCAAGAAAGCAGAGAATCTCATTCA
AGGCCAATTTGAAGGCTCTAAAACAATGGAACAGTGCTACACAGATGTGACTGAATTTGCCATTCCAGTAAGTACTCAAA
AGCTTTACTTATCACCAGTTTTAGATGGCTTTAATAGCGAAATTATCGCCTATAATCTTTCAACTTCACCCAACTTAGAA
CAAGTACAAACAATGTTGGAACAGGCATTCACAGAGAAGCACTACGAGAATACGATTCTCCATAGTGACCAAGGCTGGCA
ATATCAACACGATTCTTATCATCGGTTCCTAGAGAGTAAGGGAATTCAAGCATCTATGTCACGCAAGGGAAACAGCCCAG
ACAACGGCATGATGGAATCTTTCTTTGGCATTTTGAAATCGGAGATGTTTTATGGTTATGAGAAGAACTTTAGATCTTTA
GAAAACCTTGAACAAGCTATTGTGGACTATATTGATTACTACAACAATAAACGAATTAAGGTAAAACTAAAAGGACTTAG
CCCTGTGCAATACAGAACTAAATCCTTCGGATAA

Upstream 100 bases:

>100_bases
AGTACCTGAGAGCGGAGAATGCCATCCTAAAAAAGTTAAGAGAACTCCGATTGAAGGAGGAAAAAGAGAAAGAAGAAAGA
CAGAAATTGTTCAAGAATTA

Downstream 100 bases:

>100_bases
ATTAATTGTCTAACTTTTGGGGTGCAGTTCACAGAACTGGCATTTTATTTTTTAGGATCTTGATGGGTTAAGTTCAATCC
CCAAGGGACCAAATTTTCAG

Product: integrase core subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MTEFSLVLLLKSIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRVHLELRNRAYLVNHKRVQGLIKVLN
LQAKTRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYNLSTSPNLE
QVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSL
ENLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

Sequences:

>Translated_277_residues
MTEFSLVLLLKSIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRVHLELRNRAYLVNHKRVQGLIKVLN
LQAKTRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYNLSTSPNLE
QVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSL
ENLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
>Mature_276_residues
TEFSLVLLLKSIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRVHLELRNRAYLVNHKRVQGLIKVLNL
QAKTRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCYTDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQ
VQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLE
NLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=235, Percent_Identity=29.3617021276596, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1789981, Length=274, Percent_Identity=47.0802919708029, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788405, Length=282, Percent_Identity=28.0141843971631, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787263, Length=282, Percent_Identity=28.0141843971631, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786753, Length=282, Percent_Identity=28.0141843971631, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786570, Length=282, Percent_Identity=28.0141843971631, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786490, Length=282, Percent_Identity=28.0141843971631, Blast_Score=107, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32506; Mature: 32375

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFSLVLLLKSIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRVHLEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEH
RNRAYLVNHKRVQGLIKVLNLQAKTRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCY
HCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHH
TDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTIL
HHHHHHCCCCCCHHEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEE
HSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSL
ECCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHH
ENLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCC
>Mature Secondary Structure 
TEFSLVLLLKSIKLARWTYYYHLKQLDKTDKDQELKAEIQSIFIEHKGNYAYRRVHLEL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEH
RNRAYLVNHKRVQGLIKVLNLQAKTRQKRKYSSHKGDVGKKAENLIQGQFEGSKTMEQCY
HCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHH
TDVTEFAIPVSTQKLYLSPVLDGFNSEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTIL
HHHHHHCCCCCCHHEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEE
HSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSL
ECCCCCCCCCHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHH
ENLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
HHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]