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The map label for this gene is tehB [H]

Identifier: 169833107

GI number: 169833107

Start: 993880

End: 994740

Strand: Direct

Name: tehB [H]

Synonym: SPH_1078

Alternate gene names: 169833107

Gene position: 993880-994740 (Clockwise)

Preceding gene: 169833807

Following gene: 169834084

Centisome position: 44.26

GC content: 42.28

Gene sequence:

>861_bases
ATGGAAAAATTAGTTGCCTATAAACGCATGCCTTTGTGGAATAAACAAACAATGCCTGAAGCTGTTCAGCAAAAGCACAA
TACAAAAGTTGGGACTTGGGGGAAAATTACTGTCTTGAAGGGAGCTCTCAAGTTTATTGAATTGACAGAAGAAGGGGAAG
TTCTAGCTGAACACCTCTTTGAAGCAGGGGCAGACAATCCAATGGCCCAACCTCAAGCCTGGCACCGAGTGGAAGCTGCC
ACAGATGATGTGGAATGGTACTTGGAATTTTATTGTAAACCTGAGGATTATTTTGCTAAAAAATACAATACCAATCCTGT
TCATTCAGAGGTCCTAGAGGCCATGCAGACAGTGAAACAAGGGAAAGCTTTGGATTTGGGTTGTGGTCAGGGGCGTAATT
CTCTTTTTCTAGCCCAGCAAGATTTTGATGTGACGGCTGTAGATCAAAATGGACTGGCTCTTGAAATCTTGCAAAGCATT
GTGGAGCAGGAAGATTTGGACATGCCTGTTGGCCTTTACGATATCAATTCAGCTAGCATTGGACAAGAATATGATTTTAT
CGTTTCAACAGTTGTTCTCATGTTTCTACAAGCGGACCGCATTCCAGCTATTATTCAAAATATGCAGGAGAAAACCAGTG
TTGGTGGTTACAACCTTATCGTTTGTGCCATGGACACGGAGGATTATCCTTGCTCGGTTAACTTCCCATTCACCTTTAAA
GAAGGAGAACTGGCAGACTATTACAAGGATTGGGAATTGGTTAAGTACAATGAAAATCCAGGCCATTTGCACCGTCGCGA
TGAGAATGGCAATCGTATTCAACTACGCTTTGCGACCTTACTAGCTAAGAAAATCAAGTAA

Upstream 100 bases:

>100_bases
TGACTATGACAAACGGGAGTCTATCAAACGTCGTGAGCAAAATCGAGATATCGCGCGTGTGATGAAAGCTGTTAATCAGC
GATAAAAAGAGGAATTGAAA

Downstream 100 bases:

>100_bases
ACACACATGAAGATTAGGAATTTTCCTGATCTTTTTTCTTTTTTACGAATGATATAGAAAAGGAGGGAATTCATGTTTGT
TGCGAGAGATGCTAGGGGAG

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAA
TDDVEWYLEFYCKPEDYFAKKYNTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK

Sequences:

>Translated_286_residues
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAA
TDDVEWYLEFYCKPEDYFAKKYNTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK
>Mature_286_residues
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAA
TDDVEWYLEFYCKPEDYFAKKYNTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm. Note=Probably a peripheral membrane protein that interacts with TehA (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family [H]

Homologues:

Organism=Escherichia coli, GI1787700, Length=193, Percent_Identity=58.0310880829015, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1788098, Length=99, Percent_Identity=30.3030303030303, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015392
- InterPro:   IPR014710
- InterPro:   IPR004537
- InterPro:   IPR014431
- InterPro:   IPR015985 [H]

Pfam domain/function: PF09313 DUF1971; PF03848 TehB [H]

EC number: NA

Molecular weight: Translated: 32613; Mature: 32613

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLF
CCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHEEECCCHHHHHHHHH
EAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKYNTNPVHSEVLEAMQTVKQ
HCCCCCCCCCCHHHHHHHHCCCHHEEEEHEEECCHHHHHHCCCCCCHHHHHHHHHHHHHC
GKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSIVEQEDLDMPVGLYDINSASI
CCEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCC
GQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEECCCEEEC
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK
CCCHHHHHCCCEEEEECCCCCCCEECCCCCCEEEEEHHHHHHHHCC
>Mature Secondary Structure
MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALKFIELTEEGEVLAEHLF
CCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHEEECCCHHHHHHHHH
EAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKYNTNPVHSEVLEAMQTVKQ
HCCCCCCCCCCHHHHHHHHCCCHHEEEEHEEECCHHHHHHCCCCCCHHHHHHHHHHHHHC
GKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSIVEQEDLDMPVGLYDINSASI
CCEEECCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCC
GQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYNLIVCAMDTEDYPCSVNFPFTFK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEECCCEEEC
EGELADYYKDWELVKYNENPGHLHRRDENGNRIQLRFATLLAKKIK
CCCHHHHHCCCEEEEECCCCCCCEECCCCCCEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]