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The map label for this gene is ywcF [H]

Identifier: 169833082

GI number: 169833082

Start: 838138

End: 839388

Strand: Direct

Name: ywcF [H]

Synonym: SPH_0905

Alternate gene names: 169833082

Gene position: 838138-839388 (Clockwise)

Preceding gene: 169833275

Following gene: 169833282

Centisome position: 37.32

GC content: 40.05

Gene sequence:

>1251_bases
TTGTATGAAAGTATAAGGTTAGTATATATGAAACGTTCTCTCGACTCAAGAGTCGATTACAGTTTGCTCTTGCCAGTATT
TTTTCTACTGGTCATCGGTGTGGTGGCTATCTATATAGCCGTTAGTCATGATTATCCCAATAATATTCTGCCCATTTTAG
GGCAGCAGGTCGCCTGGATTGCCTTGGGGCTTGTGATTGGTTTTGTGGTCATGCTCTTTAATACAGAATTTCTTTGGAAG
GTGACCCCCTTTCTATATATTTTAGGCTTGGGACTTATGATCTTGCCGATTGTATTTTATAATCCAAGCTTAGTTGCATC
AACGGGTGCCAAAAACTGGGTATCAATAAATGGAATTACCCTATTCCAACCGTCAGAATTTATGAAGATATCCTATATCC
TCATGTTGGCTCGTGTCATTGTCCAATTTACAAAGAAACATAAGGAATGGAGACGCACGGTTCCGCTGGACTTTTTGTTA
ATTTTCTGGATGATTCTCTTTACCATTCCAGTCCTAGTTCTTTTAGCACTTCAAAGTGACTTGGGGACGGCTTTGGTTTT
TGTAGCCATTTTCTCAGGAATCGTTTTATTATCAGGGGTTTCTTGGAAAATTATTATCCCAGTATTTGTGACTGCTGTAA
CAGGAGTTGCTGGTTTCTTAGCTATCTTTATTAGCAAGGACGGACGAGCTTTTCTTCACCAGATTGGAATGCCGACCTAC
CAAATCAATCGGATTTTGGCTTGGCTCAATCCCTTTGAGTTTGCCCAAACAACGACTTACCAGCAGGCTCAAGGGCAGAT
TGCCATTGGGAGTGGTGGCTTATTTGGTCAGGGATTTAATGCTTCGAATCTGCTTATCCCAGTTCGAGAGTCAGATATGA
TTTTTACGGTTATTGCAGAAGATTTTGGCTTTATTGGCTCTGTCCTGGTTATTGCCCTCTATCTCATGTTGATTTACCGT
ATGTTGAAGATTACTCTTAAATCAAATAACCAGTTCTACACTTATATTTCCACAGGTTTGATTATGATGTTGCTCTTCCA
CATCTTTGAGAATATCGGTGCTGTGACTGGACTACTTCCTTTGACGGGGATTCCCTTGCCTTTCATTTCGCAAGGGGGAT
CAGCTATTATCAGTAATCTGATTGGTGTTGGTTTGCTTTTATCGATGAGTTACCAGACTAATCTAGCTGAAGAAAAGAGC
GGAAAAGTCCCATTCAAACGGAAAAAGGTTGTATTAAAACAAATTAAATAA

Upstream 100 bases:

>100_bases
AGTAGCATCTCTAGCAGAAGAAGCGACTGTTAAAACCATCTCTCGATCCGAAGTTGACGAGGCTATTGATAGATTTTTTA
ATGAACTTTGATAAATAGTA

Downstream 100 bases:

>100_bases
GGAGAAAATCATGGTAAAAGTAGCAGTTATGTTAGCTCAGGGCTTTGAAGAAATTGAAGCCTTGACAGTTGTAGATGTCT
TGCGTCGAGCCAATATCACA

Product: RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MYESIRLVYMKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFVVMLFNTEFLWK
VTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLL
IFWMILFTIPVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTY
QINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYR
MLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKS
GKVPFKRKKVVLKQIK

Sequences:

>Translated_416_residues
MYESIRLVYMKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFVVMLFNTEFLWK
VTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLL
IFWMILFTIPVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTY
QINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYR
MLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKS
GKVPFKRKKVVLKQIK
>Mature_416_residues
MYESIRLVYMKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWIALGLVIGFVVMLFNTEFLWK
VTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLL
IFWMILFTIPVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTY
QINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYR
MLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKS
GKVPFKRKKVVLKQIK

Specific function: This Is One Of The Proteins Responsible For The Rod Shape Of E. coli. Is Required For The Expression Of The Enzymatic Activity Of Pbp2, Which Is Thought To Synthesize Peptidoglycan In The Step Of Initiation Of Cell Elongation. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=355, Percent_Identity=33.5211267605634, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786277, Length=402, Percent_Identity=25.6218905472637, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46391; Mature: 46391

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYESIRLVYMKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWI
CCCCEEEHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGIT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEECCEE
LFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTIPVLVLLALQSD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTY
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHH
QINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAE
HHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEEEHHH
DFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLP
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKKVVLKQIK
HCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MYESIRLVYMKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPILGQQVAWI
CCCCEEEHEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAKNWVSINGIT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEECCEE
LFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTIPVLVLLALQSD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKDGRAFLHQIGMPTY
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHH
QINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLLIPVRESDMIFTVIAE
HHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCEEEEEHHH
DFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMMLLFHIFENIGAVTGLLP
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSGKVPFKRKKVVLKQIK
HCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]