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The map label for this gene is ykpA [H]

Identifier: 169832977

GI number: 169832977

Start: 2234104

End: 2235726

Strand: Direct

Name: ykpA [H]

Synonym: SPH_2425

Alternate gene names: 169832977

Gene position: 2234104-2235726 (Clockwise)

Preceding gene: 169832646

Following gene: 169834282

Centisome position: 99.49

GC content: 38.76

Gene sequence:

>1623_bases
TTGCTTACAGTATCTGATGTTTCACTACGTTTTAGTGATCGCAAACTTTTTGATGATGTCAATATCAAATTTACAGAAGG
AAATACTTACGGATTAATCGGTGCTAATGGTGCCGGAAAATCAACCTTTTTAAAAATTTTAGCTGGAGATATCGAACCTA
CTACTGGTCACATCTCTCTTGGTCCAGATGAACGTCTCTCTGTTCTTCGTCAAAATCACTTTGACTACGAAGATGAACGT
GCCATTGATGTCGTTATCATGGGAAATGAAAAACTTTATAGCATCATGAAAGAGAAAGATGCTATCTACATGAAGGAAGA
TTTCTCAGACGAGGACGGGGTTCGTGCTGCCGAACTCGAAGGAGAGTTTGCCGAACTTGGAGGTTGGGAAGCAGAGAGTG
AAGCCTCTCAACTACTTCAAAACCTAAACATTCCAGAAGAATTACACTACCAAAACATGAGCGAATTGGCCAACGGTGAA
AAAGTAAAGGTTCTCCTCGCCAAAGCACTTTTTGGTAAACCAGATGTTCTTCTCTTGGACGAGCCTACTAACGGTTTGGA
TATCCAATCGATTACTTGGTTAGAAGACTTCTTGATTGACTTTGATAACACAGTTATCGTAGTATCCCACGACCGTCACT
TCTTAAACAAAGTTTGTACTCACATGGCCGACCTTGACTTTGGAAAAATCAAACTCTATGTCGGAAACTACGACTTCTGG
AAGGAATCTTCTGAGCTTGCTGCTAAATTGCTAGCAGACCGTAATGCTAAAGCAGAAGAAAAAATTAAACAATTGCAAGA
ATTCGTTGCTCGTTTCTCTGCCAATGCTTCTAAGTCAAGGCAGGCAACATCACGTAAGAAAATGCTTGATAAGATTGAGC
TAGAAGAGATTGTACCATCTAGTCGTAAATATCCATTTATCAACTTTAAAGCGGAACGTGAGATTGGTAATGATCTCTTG
ACAGTAGAAAATCTAACTGTAAAGATTGATGGTGAAACTATCTTGGATAATATTAGTTTCATCTTGCGTCCAGATGATAA
GACAGCACTTATTGGACAAAATGATATTCAAACGACTGCATTAATTCGTGCAATCATGGGAGATATTGACTATGAAGGAA
CTGTCAAGTGGGGAGTTACAACTAGTCAATCTTACCTACCAAAAGATAACTCAGCTGATTTTGCAGGAGGAGAATCAATT
CTTGACTGGTTGCGTCAATTCGCAAGTAAAGAAGATGATGACAATACTTTCCTACGTGGTTTCCTCGGCCGTATGCTCTT
CTCTGGAGATGAAGTTAACAAACCTGTAAATGTCTTGTCAGGGGGAGAAAAAGTTCGTGTCATGCTTTCAAAACTCATGC
TCTTAAAATCAAATGTCCTTGTACTTGATGATCCAACAAATCACTTGGACTTGGAATCTATCTCAAGCTTGAATGATGGA
TTGAAAAACTTTAAAGAATCAATCATCTTTGCCAGCCATGACCACGAGTTTATTCAAACTTTGGCTAACCATATCATTGT
CTTATCTAAAAATGGCGTCATTGACCGTATCGATGAAACCTACGATGAATTCCTAGAAAATGCAGAAGTACAAGCAAAAG
TTAAAGAACTTTGGAAAGACTAA

Upstream 100 bases:

>100_bases
GATACTGTAAATATAATTTACACAAAATTGACAAATAAAAATTTGAATATTTCTGTATTTTCTAGTAGAATAAATATATT
ACACATATAGGAGAAAAACA

Downstream 100 bases:

>100_bases
ATAAAACTTCAAAACTCAGTTGGGTTAACCAACTGAGTTTTCTATCATTCTACGAGGTAACATGAAATCATTTTTAAAAA
CATATCGAACCTATTTTATT

Product: ABC transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFLKILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDER
AIDVVIMGNEKLYSIMKEKDAIYMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKVCTHMADLDFGKIKLYVGNYDFW
KESSELAAKLLADRNAKAEEKIKQLQEFVARFSANASKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLL
TVENLTVKIDGETILDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSADFAGGESI
LDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLSKLMLLKSNVLVLDDPTNHLDLESISSLNDG
LKNFKESIIFASHDHEFIQTLANHIIVLSKNGVIDRIDETYDEFLENAEVQAKVKELWKD

Sequences:

>Translated_540_residues
MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFLKILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDER
AIDVVIMGNEKLYSIMKEKDAIYMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKVCTHMADLDFGKIKLYVGNYDFW
KESSELAAKLLADRNAKAEEKIKQLQEFVARFSANASKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLL
TVENLTVKIDGETILDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSADFAGGESI
LDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLSKLMLLKSNVLVLDDPTNHLDLESISSLNDG
LKNFKESIIFASHDHEFIQTLANHIIVLSKNGVIDRIDETYDEFLENAEVQAKVKELWKD
>Mature_540_residues
MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFLKILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDER
AIDVVIMGNEKLYSIMKEKDAIYMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKVCTHMADLDFGKIKLYVGNYDFW
KESSELAAKLLADRNAKAEEKIKQLQEFVARFSANASKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLL
TVENLTVKIDGETILDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSADFAGGESI
LDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLSKLMLLKSNVLVLDDPTNHLDLESISSLNDG
LKNFKESIIFASHDHEFIQTLANHIIVLSKNGVIDRIDETYDEFLENAEVQAKVKELWKD

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=535, Percent_Identity=30.2803738317757, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI10947137, Length=524, Percent_Identity=30.5343511450382, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI27881506, Length=524, Percent_Identity=30.5343511450382, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI69354671, Length=552, Percent_Identity=26.0869565217391, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI10947135, Length=550, Percent_Identity=25.8181818181818, Blast_Score=159, Evalue=7e-39,
Organism=Escherichia coli, GI1787041, Length=533, Percent_Identity=46.9043151969981, Blast_Score=516, Evalue=1e-147,
Organism=Escherichia coli, GI1789751, Length=532, Percent_Identity=30.0751879699248, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI2367384, Length=536, Percent_Identity=28.544776119403, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1787182, Length=524, Percent_Identity=28.4351145038168, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1788165, Length=200, Percent_Identity=24.5, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788450, Length=277, Percent_Identity=26.3537906137184, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789864, Length=219, Percent_Identity=24.6575342465753, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=223, Percent_Identity=22.8699551569507, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786398, Length=231, Percent_Identity=24.2424242424242, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=525, Percent_Identity=27.6190476190476, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17553372, Length=556, Percent_Identity=27.6978417266187, Blast_Score=199, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI17559834, Length=531, Percent_Identity=25.2354048964218, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI115533608, Length=237, Percent_Identity=27.8481012658228, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=525, Percent_Identity=31.8095238095238, Blast_Score=236, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6321121, Length=560, Percent_Identity=28.5714285714286, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6325030, Length=594, Percent_Identity=25.0841750841751, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324314, Length=374, Percent_Identity=24.5989304812834, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323278, Length=251, Percent_Identity=27.4900398406374, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666836, Length=533, Percent_Identity=28.3302063789869, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24642252, Length=551, Percent_Identity=26.8602540834846, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI18859989, Length=551, Percent_Identity=26.8602540834846, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24641342, Length=524, Percent_Identity=26.1450381679389, Blast_Score=186, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60857; Mature: 60857

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFLKILAGDIEPTTGHISL
CEEEECEEEEECCCHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCCCEEEC
GPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAIYMKEDFSDEDGVRAAELE
CCHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHCCCEEEECCCCCCCCCEEECCC
GEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGEKVKVLLAKALFGKPDVLLLD
CCHHHCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEHHHCCCCCEEEEE
EPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKVCTHMADLDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHH
KESSELAAKLLADRNAKAEEKIKQLQEFVARFSANASKSRQATSRKKMLDKIELEEIVPS
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
SRKYPFINFKAEREIGNDLLTVENLTVKIDGETILDNISFILRPDDKTALIGQNDIQTTA
CCCCCEEEEEEHHHCCCCEEEEEEEEEEECCHHHCCCCEEEECCCCCEEEECCCCHHHHH
LIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSADFAGGESILDWLRQFASKEDDDNTFLRG
HHHHHHCCCCCCCEEEECEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
FLGRMLFSGDEVNKPVNVLSGGEKVRVMLSKLMLLKSNVLVLDDPTNHLDLESISSLNDG
HHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHH
LKNFKESIIFASHDHEFIQTLANHIIVLSKNGVIDRIDETYDEFLENAEVQAKVKELWKD
HHHHHHHEEEECCCHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFLKILAGDIEPTTGHISL
CEEEECEEEEECCCHHCCCCEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCCCCCEEEC
GPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAIYMKEDFSDEDGVRAAELE
CCHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHCCCEEEECCCCCCCCCEEECCC
GEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGEKVKVLLAKALFGKPDVLLLD
CCHHHCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHCCCCEEEEEEEHHHCCCCCEEEEE
EPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKVCTHMADLDFGKIKLYVGNYDFW
CCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHH
KESSELAAKLLADRNAKAEEKIKQLQEFVARFSANASKSRQATSRKKMLDKIELEEIVPS
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
SRKYPFINFKAEREIGNDLLTVENLTVKIDGETILDNISFILRPDDKTALIGQNDIQTTA
CCCCCEEEEEEHHHCCCCEEEEEEEEEEECCHHHCCCCEEEECCCCCEEEECCCCHHHHH
LIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSADFAGGESILDWLRQFASKEDDDNTFLRG
HHHHHHCCCCCCCEEEECEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHH
FLGRMLFSGDEVNKPVNVLSGGEKVRVMLSKLMLLKSNVLVLDDPTNHLDLESISSLNDG
HHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHH
LKNFKESIIFASHDHEFIQTLANHIIVLSKNGVIDRIDETYDEFLENAEVQAKVKELWKD
HHHHHHHEEEECCCHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]