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The map label for this gene is speG [C]

Identifier: 169832911

GI number: 169832911

Start: 319786

End: 320481

Strand: Direct

Name: speG [C]

Synonym: SPH_0374

Alternate gene names: 169832911

Gene position: 319786-320481 (Clockwise)

Preceding gene: 169834287

Following gene: 169832834

Centisome position: 14.24

GC content: 45.69

Gene sequence:

>696_bases
ATGCCAGTAAATGAATATGGTCAGATGATTGGTGAGTCAATGGAAGGTTATACACCCGGTGCACTGCCTTCTATTGATTT
CTTAGAAGGGCGTTATGCTAGGATAGAGGCTCTCTCGGTAGAAAAACATGCGGAGGATTTGCTAGCTGTTTATGGCCCGG
ATACTCCTCGGGAGATGTGGACCTATCTTTTTCAGGAGCCAGTAGCAGATATGGGGGAGCTGGTTAGCCTTTTAAATCAG
ATGTTGGCTCGTAAGGACCGTTTTTACTATGCAATCATAGACAAGGCGACTGGTAAGGCTTTGGGAACTTTTTCTCTCAT
GCGCATTGACCAGAATAACCGAGTAATAGAAGTCGGAGCAGTCACTTTTTCTCCAGAGCTAAGGGGTACACGGATAGGAA
CTGAGGCTCAGTATCTCCTAGCTCGCTATATTTTTGAGGAGCTAAACTATCGTCGCTACGAGTGGAAATGCGATGCCTTA
AATCTGCCATCCAGACGAGTTGCGGAGCGTTTGGGATTTGTCTATGAAGGAACCTTCCGCCAGGCGGTGGTTTATAAGGG
GCGTACGAGAGATACGGATTGGTTGTCTATGATTGATATGGACTGGCCTCAAGTCAAAGATCGTTTGGAAACATGGCTGC
GTCCTGAAAATTTTGATAAAAATGGACAGCAGTACAAGAGCTTGAGAGAACTTTAA

Upstream 100 bases:

>100_bases
AAATTGTTAAATGAAATTGATAAAAAACTTGAAATTAGCAGATAGGACAATTCAAATAGAGTTGAGTAAAAAGTTTGAAA
AGTGAAACAAGGAGAAAGCT

Downstream 100 bases:

>100_bases
GAGGTGTTGAGATGATTACTATTAAAAAGCAAGAAATTGTCAAGCTAGAGGATGTTTTGCATCTCTATCAGGCTGTCGGT
TGGACAAATTATACCCATCA

Product: acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: Acetyltransferase; GNAT Family Acetyltransferase; Acetyltransferase GNAT Family; Acetyltransferase Gnat Family; Amino-Acid Acetyltransferase; Ribosomal Protein Serine Acetyltransferase; GCN5-Like N-Acetyltransferase; Ribosomal-Protein-Serine Acetyltransferase; Gcn5-Related N-Acetyltransferase; Acetyltransferase Protein; Ribosomal-Protein-Alanine Acetyltransferase; Acetyltransferase GNAT Family Protein; Ypothetical Protein SMU.; Acetyltransferase/N-Acetylase

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHAEDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQ
MLARKDRFYYAIIDKATGKALGTFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENFDKNGQQYKSLREL

Sequences:

>Translated_231_residues
MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHAEDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQ
MLARKDRFYYAIIDKATGKALGTFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENFDKNGQQYKSLREL
>Mature_230_residues
PVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHAEDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQM
LARKDRFYYAIIDKATGKALGTFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDALN
LPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENFDKNGQQYKSLREL

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6322233, Length=226, Percent_Identity=48.2300884955752, Blast_Score=225, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 26956; Mature: 26825

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHAEDLLAVYGPDTPREMW
CCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHEEHHHHHHHHHHEEECCCCCHHHHH
TYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALGTFSLMRIDQNNRVIEVGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHEEEEEECCCCCEEEEEE
VTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDALNLPSRRVAERLGFVYEGTFR
EEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCHHCCCHH
QAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENFDKNGQQYKSLREL
HHEEECCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
PVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHAEDLLAVYGPDTPREMW
CHHHHHHHHHHHCCCCCCCCCCCCHHHCCCHHHHEEHHHHHHHHHHEEECCCCCHHHHH
TYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALGTFSLMRIDQNNRVIEVGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHEEEEEECCCCCEEEEEE
VTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDALNLPSRRVAERLGFVYEGTFR
EEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCHHCCCHH
QAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENFDKNGQQYKSLREL
HHEEECCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA