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The map label for this gene is mraY [H]

Identifier: 169832846

GI number: 169832846

Start: 395548

End: 396528

Strand: Direct

Name: mraY [H]

Synonym: SPH_0447

Alternate gene names: 169832846

Gene position: 395548-396528 (Clockwise)

Preceding gene: 169833971

Following gene: 169833188

Centisome position: 17.61

GC content: 41.39

Gene sequence:

>981_bases
ATGTTTATTTCCATCAGTGCTGGAATTGTGACATTTTTACTAACTTTAGTAGGAATTCCGGCCTTTATCCAATTTTATAG
AAAGGCGCAAATTACAGGCCAGCAGATGCATGAGGATGTCAAACAGCACCAGGCAAAAGCTGGCACGCCAACTATGGGGG
GACTTATTTTCCTCATTGCTGCAGTTGTGGTGAGTTTCCTTGTTGCTCTTTTTTCAAAACAATTGACCAATAATGTGGGA
ATGATTTTGTTCATCTTGGTCTTGTATGGCTTGGTCGGATTTTTAGATGACTTTCTTAAGGTTTTTCGTAAAATCAATGA
GGGGCTGAATCCTAAGCAAAAATTGGCACTTCAACTTCTAGGTGGCGTCATTTTCTATCTTTTCTATGAGCGAGGTGGCG
ATATGCTTTCAATCTTTGGCTACCAAGTGCATCTAGGGATTTTCTATATTGTCTTTGCTCTTTTCTGGCTAGTCGGTTTT
TCAAATGCAGTCAACTTGACAGACGGAATTGATGGTCTGGCTAGTATTTCCGTTGTGATTAGTTTGTCAGCTTATGGAGT
TATTGCCTATGTGCAAGGTCAGATGGATATCCTTCTGGTGATTCTCGCTATGATTGGTGGTTTGCTCGGTTTCTTCGTCT
TTAACCATAAGCCTGCTAAGGTCTTTATGGGAGATGTGGGAAGTTTGGCTCTCGGTGGAATGCTGGCAGCTATCTCTATG
GCCCTCCACCAAGAATGGACTCTATTGATTATCGGAATTGTTTATGTTTTTGAAACAACTTCGGTCATGATGCAAGTCAG
TTATTTCAAACTGACAGGTGGTAAACGTATTTTCCGTATGACGCCTGTCCATCACCATTTTGAACTTGGGGGATTGTCTG
GTAAAGGAAATCCTTGGAGTGAGTGGAAGGTTGACTTCTTCTTTTGGGGAGTGGGACTTCTAGCAAGTCTTTTGACGCTA
GCAATTTTGTATTTGAGATAA

Upstream 100 bases:

>100_bases
GAATTTGAAGGTTCAGGTTCCATCGTTCAGAAGCAAGATGTTCGGACTAATACAGCTATCAAAAACATTAAAAAAATTAA
ATTAACTTTAGGAGACTAAT

Downstream 100 bases:

>100_bases
GAATGGCACCCTGATGTTTCAGGGTGTTTTTGCTGTTTAAAAAATATTGGTCAATTAAAGTCAAATCTCTTGACCTTTTC
TGACCAATGTAGTATATTAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLIFLIAAVVVSFLVALFSKQLTNNVG
MILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSIFGYQVHLGIFYIVFALFWLVGF
SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKPAKVFMGDVGSLALGGMLAAISM
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTL
AILYLR

Sequences:

>Translated_326_residues
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLIFLIAAVVVSFLVALFSKQLTNNVG
MILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSIFGYQVHLGIFYIVFALFWLVGF
SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKPAKVFMGDVGSLALGGMLAAISM
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTL
AILYLR
>Mature_326_residues
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLIFLIAAVVVSFLVALFSKQLTNNVG
MILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSIFGYQVHLGIFYIVFALFWLVGF
SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKPAKVFMGDVGSLALGGMLAAISM
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTL
AILYLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=320, Percent_Identity=41.5625, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35919; Mature: 35919

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLIFLIA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AVVVSFLVALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GGVIFYLFYERGGDMLSIFGYQVHLGIFYIVFALFWLVGFSNAVNLTDGIDGLASISVVI
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKPAKVFMGDVGSLALGGMLAAISM
HHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHCEEECCCCCCCCCCC
EWKVDFFFWGVGLLASLLTLAILYLR
HHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQAKAGTPTMGGLIFLIA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AVVVSFLVALFSKQLTNNVGMILFILVLYGLVGFLDDFLKVFRKINEGLNPKQKLALQLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GGVIFYLFYERGGDMLSIFGYQVHLGIFYIVFALFWLVGFSNAVNLTDGIDGLASISVVI
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
SLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKPAKVFMGDVGSLALGGMLAAISM
HHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHH
ALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKRIFRMTPVHHHFELGGLSGKGNPWS
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHCEEECCCCCCCCCCC
EWKVDFFFWGVGLLASLLTLAILYLR
HHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA