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The map label for this gene is gcp [H]

Identifier: 169832476

GI number: 169832476

Start: 212101

End: 213111

Strand: Direct

Name: gcp [H]

Synonym: SPH_0244

Alternate gene names: 169832476

Gene position: 212101-213111 (Clockwise)

Preceding gene: 169832924

Following gene: 169833354

Centisome position: 9.45

GC content: 49.75

Gene sequence:

>1011_bases
ATGAAGGATAGATATATTTTAGCATTTGAGACATCCTGTGATGAGACCAGTGTCGCCGTCTTGAAAAACGACGATGAGCT
CTTGTCCAATGTCATTGCTAGTCAAATTGAGAGTCACAAACGTTTTGGTGGCGTAGTGCCCGAAGTAGCCAGTCGTCACC
ATGTCGAGGTCATTACAGCCTGTATCGAGGAGGCATTGGCAGAAGCAGGGATTACCGAAGAGGACGTGACAGCTGTTGCG
GTTACCTATGGACCGGGCTTAGTCGGAGCCTTGCTAGTTGGCTTGTCAGCTGCCAAGACCTTTGCTTGGGCTCACGGACT
TCCGCTGATCCCTGTTAATCACATGGCTGGGCACCTCATGGCCGCTCAGAGTGTGGAGCCTTTGGAGTTTCCTTTGTTGG
CACTCTTGGTCAGCGGTGGCCACACAGAGTTGGTCTATGTTTCTGAGGCTGGCGATTACAAGATTGTTGGGGAGACACGA
GATGACGCGGTTGGCGAGGCCTATGATAAGGTCGGCCGTGTCATGGGCTTGACCTATCCTGCAGGTCGTGAGATTGACGA
GCTGGCTCATCAGGGGCAGGATATTTATGATTTCCCCCGTGCCATGATTAAGGAAGATAATCTGGAGTTTTCATTCTCTG
GTTTGAAGTCAGCCTTTATCAATCTTCATCACAATGCCGAGCAAAAGGGAGAAAGCCTGTCTACAGAAGATTTGTGTGCT
TCCTTCCAAGCAGCAGTTATGGACATTCTCATGGCAAAAACCAAGAAGGCTTTGGAGGAATATCCTGTTAAAACCCTAGT
TGTGGCAGGTGGTGTGGCAGCCAATAAAGGTCTCAGAGAACGCTTAGCAGCCGAAATCACAGATGTCAAGGTTATCATCC
CCCCTCTGCGACTCTGCGGAGACAATGCAGGTATGATTGCCTATGCCAGCGTCAGCGAGTGGAACAAAGAAAACTTCGCA
GGCTGGGACCTCAATGCCAAACCAAGTCTTGCCTTTGATACCATGGAATAA

Upstream 100 bases:

>100_bases
CAAGCATTTTACAAGAAAGAAAAGATGGCAGTTATCGCTGAGCGAAAGGCCTACTACCATGACCCAGTCGAGGACGCCAT
TATCATGAAGAGAGAAATAG

Downstream 100 bases:

>100_bases
AGAGTGGCTCTTTGTCAAGTGTAGTGGGTAGGCGAAAAGTTACAATCTGGAGAGTACGAAATTCGTACTCTCTTTTTTGA
TGTTCAAAGTCATCAAAATC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVA
VTYGPGLVGALLVGLSAAKTFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCA
SFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFA
GWDLNAKPSLAFDTME

Sequences:

>Translated_336_residues
MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVA
VTYGPGLVGALLVGLSAAKTFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCA
SFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFA
GWDLNAKPSLAFDTME
>Mature_336_residues
MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVA
VTYGPGLVGALLVGLSAAKTFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCA
SFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFA
GWDLNAKPSLAFDTME

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=336, Percent_Identity=33.6309523809524, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI8923380, Length=309, Percent_Identity=32.6860841423948, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1789445, Length=327, Percent_Identity=43.7308868501529, Blast_Score=267, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=352, Percent_Identity=33.8068181818182, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71995670, Length=311, Percent_Identity=31.1897106109325, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=342, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322891, Length=355, Percent_Identity=28.4507042253521, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20129063, Length=355, Percent_Identity=34.6478873239437, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21357207, Length=317, Percent_Identity=29.9684542586751, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36205; Mature: 36205

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITA
CCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHH
CIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFAWAHGLPLIPVNHMAGHLM
HHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLTYP
HHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
AGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCA
CCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHCCCCCCHHHHHH
SFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCG
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCEEEEECCHHHCC
DNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDTME
CCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITA
CCCCEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHH
CIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFAWAHGLPLIPVNHMAGHLM
HHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLTYP
HHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
AGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCA
CCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHCCCCCCHHHHHH
SFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCG
HHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCEEEEECCHHHCC
DNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDTME
CCCCEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA