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The map label for this gene is appC [H]

Identifier: 169825257

GI number: 169825257

Start: 1731132

End: 1731947

Strand: Direct

Name: appC [H]

Synonym: FMG_1560

Alternate gene names: 169825257

Gene position: 1731132-1731947 (Clockwise)

Preceding gene: 169825256

Following gene: 169825258

Centisome position: 96.3

GC content: 35.66

Gene sequence:

>816_bases
ATGAAAAAACTTTTTAAAAATTTTAAATTAAGTCCCCTTAGGGTCAAATTTTCTGTTACACTTCTTCTACTCTTCATATT
AGCTGCTGTATTAGCAGACCTATATCCTAAAAACGGTATAGATACTGACATAACCAATGCACTGGTTCCACCAAATAGCG
AAAATTTTTTTGGAACTGACGACTTAGGTAGAGATTACTTTGCTAGGGCATTACATGGCGCAAGGGCCTCCCTTACAGTT
GGTGTGCTATCGGTTGTTATTTCAACCATATTAGGATCATTCGTTGGAATCATTTCAGGATATTTCGGCGGTAAAGTAGA
TATGATAATTATGAGAATTGTTGACATACTAATGAGTATTCCATCATTCTTTTTAATACTAATCCTAAACGCTGCTCTTA
AACCAGGAATTCAAAATATTATTATTATCATAGGACTATTTAGCTGGATGGGTATTGCAAGACTAGTTCGTGCAGAAACC
TTAACAGTTAAAGAAAGAGACTATGTAACATATTCAAAATTAATTGGAGTTGGCCACCAAAAGATAATGACAAAACACAT
TCTTAGAAACATAGTTCCCACTCTTACAGTTGCGGCTACTGTTAATGTAGCTTCTGCAATACTAACAGAGTCTTCCCTAT
CCTTCCTTGGACTTGGGGTAAGACAACCAAACTCTTCATGGGGTTCGATGTTAAAAGATGCCCAACAATATCTAGGAACT
TCACCATACTTGGCGCTTTTCCCAGGACTTTTAATTCTTTTAACAGTACTTTGCTTTAATGTAATTGGAGACTATTATAG
ACAGGAGATACAATGA

Upstream 100 bases:

>100_bases
TGGCAACTACTATGTTTGCATCTGTATTATTAATTCTTGGAAACTTAATCTCAGATATACTTTACGGAATTGTAGACCCA
AGAATAAAGGAGATGAATTA

Downstream 100 bases:

>100_bases
AATTAGTAGAAATAAAGAACTTAAATGTAGAATTTCCAGGAAAGGAATACACAACCTACGCTGTAAACAATGTAAGTTTT
GATATTTACGAAAATGAAAC

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MKKLFKNFKLSPLRVKFSVTLLLLFILAAVLADLYPKNGIDTDITNALVPPNSENFFGTDDLGRDYFARALHGARASLTV
GVLSVVISTILGSFVGIISGYFGGKVDMIIMRIVDILMSIPSFFLILILNAALKPGIQNIIIIIGLFSWMGIARLVRAET
LTVKERDYVTYSKLIGVGHQKIMTKHILRNIVPTLTVAATVNVASAILTESSLSFLGLGVRQPNSSWGSMLKDAQQYLGT
SPYLALFPGLLILLTVLCFNVIGDYYRQEIQ

Sequences:

>Translated_271_residues
MKKLFKNFKLSPLRVKFSVTLLLLFILAAVLADLYPKNGIDTDITNALVPPNSENFFGTDDLGRDYFARALHGARASLTV
GVLSVVISTILGSFVGIISGYFGGKVDMIIMRIVDILMSIPSFFLILILNAALKPGIQNIIIIIGLFSWMGIARLVRAET
LTVKERDYVTYSKLIGVGHQKIMTKHILRNIVPTLTVAATVNVASAILTESSLSFLGLGVRQPNSSWGSMLKDAQQYLGT
SPYLALFPGLLILLTVLCFNVIGDYYRQEIQ
>Mature_271_residues
MKKLFKNFKLSPLRVKFSVTLLLLFILAAVLADLYPKNGIDTDITNALVPPNSENFFGTDDLGRDYFARALHGARASLTV
GVLSVVISTILGSFVGIISGYFGGKVDMIIMRIVDILMSIPSFFLILILNAALKPGIQNIIIIIGLFSWMGIARLVRAET
LTVKERDYVTYSKLIGVGHQKIMTKHILRNIVPTLTVAATVNVASAILTESSLSFLGLGVRQPNSSWGSMLKDAQQYLGT
SPYLALFPGLLILLTVLCFNVIGDYYRQEIQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=40.2985074626866, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787054, Length=269, Percent_Identity=36.4312267657993, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1789889, Length=236, Percent_Identity=34.7457627118644, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787498, Length=253, Percent_Identity=37.1541501976285, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789964, Length=230, Percent_Identity=42.6086956521739, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788505, Length=222, Percent_Identity=35.1351351351351, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787549, Length=253, Percent_Identity=30.0395256916996, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29745; Mature: 29745

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFKNFKLSPLRVKFSVTLLLLFILAAVLADLYPKNGIDTDITNALVPPNSENFFGTD
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCC
DLGRDYFARALHGARASLTVGVLSVVISTILGSFVGIISGYFGGKVDMIIMRIVDILMSI
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PSFFLILILNAALKPGIQNIIIIIGLFSWMGIARLVRAETLTVKERDYVTYSKLIGVGHQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCHH
KIMTKHILRNIVPTLTVAATVNVASAILTESSLSFLGLGVRQPNSSWGSMLKDAQQYLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
SPYLALFPGLLILLTVLCFNVIGDYYRQEIQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLFKNFKLSPLRVKFSVTLLLLFILAAVLADLYPKNGIDTDITNALVPPNSENFFGTD
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCC
DLGRDYFARALHGARASLTVGVLSVVISTILGSFVGIISGYFGGKVDMIIMRIVDILMSI
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PSFFLILILNAALKPGIQNIIIIIGLFSWMGIARLVRAETLTVKERDYVTYSKLIGVGHQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHCCHH
KIMTKHILRNIVPTLTVAATVNVASAILTESSLSFLGLGVRQPNSSWGSMLKDAQQYLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
SPYLALFPGLLILLTVLCFNVIGDYYRQEIQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]