Click here to switch to the map view.

The map label for this gene is ydeM [C]

Identifier: 169824972

GI number: 169824972

Start: 1387437

End: 1388795

Strand: Direct

Name: ydeM [C]

Synonym: FMG_1275

Alternate gene names: 169824972

Gene position: 1387437-1388795 (Clockwise)

Preceding gene: 169824965

Following gene: 169824973

Centisome position: 77.18

GC content: 33.26

Gene sequence:

>1359_bases
ATGATACATAAATACAAAATGAATGGCCACAACATTGTTTTAGATGTAAACGGTGGAAGTGTCCATGTTTTTGACGACAT
AAGTTACGATGTACTTGATTATTACAAAGATTTAAGTGCAGATGAAATAGTAGAAAAATTAGCTCAATATCCTGAAGAAT
CTGTCAGAGATTCTATCAAGGAAATTGCAGAATTGGAAAAAGCGAATATGCTTTTTTCATCGGATGATTATCTTCACATT
GAAGATTTCAAAAAGAGAGAACCTGTTTTAAAGGCAATGTGCCTTCACGTTGTTCACGATTGTAATTTGAAGTGCGAATA
TTGTTTTGCTTCACAAGGTGATTTCGGTGGACACAAAGCTTATATGACTGAAGAAGTCGGCAAAAAAGCTTTGAAATATT
TGGTTGACAATAGTGGTTCAAGAAAATTCTTGGAAGTGGATTTCTTCGGCGGAGAACCTTTAATGGATTTCGAGCTTGTT
AAGAAATTAGTTAAATACGGCAACGAAATAGCCGAGGAAAAAGGTAAGAAATTCAGATTTACTATAACTACTAATGGTGT
TTTATTAGACGATGACAAGATAGATTTTATCAACAAAAATATGCACAACGTTGTTCTTAGTCTTGATGGTAGAAAATCTG
TCAACGATAATATGAGAAAAACTTTGAATGATAAGGGCTCTTACGATTTAATCGTTCCTAAATTCCAAAAGCTTATTAAA
GGAAGAAAAGGAAAATATTATTATGTTAGAGGAACATTTACTAAGAAGAATTTGGATTTTTCAGAAGATGTAAAACATTT
CAAAGATTTGGGATTTGAATTGTCAAGTATTGAACCTGTTGTAGACAGCGATTACGATGATTACGCTATTACTAAAGAAG
ATTTGGACACTGTTTTAAATGAATACGAAAAGTTAGCAGTGGAATATGCAAAAGATCAAGTAAATGGTTCTAACTTCAAG
TTCTTCCATTTTATGGTTGATTTGACTCAAGGTCCTTGTGTTATTAAAAGAATGCAAGGTTGTGGAGCTGGCTGCGAATA
CGTTGCAGTTACTCCAGAAGGAGACATCTATCCTTGTCACCAATTTGTCGGCAATGAAAAATTCAAAATGGGCAATATTT
TAGATGAAAATCTAACTTTACCAGAAGATATGCGTGAAGAATTTTTGAATTGTCATGTATTTACAAAAGAAGATTGCAAG
AATTGTTGGTGCAAATTCTACTGTTCTGGTGGTTGCCATGCAAATGCGTACAATTTTAATAACGATATTTACAAACCTTA
TGAATTAGGTTGCGCAATGCAAAAGAAACGTACTGAATGTGCAATTATGGTTGAAGTGGAGAAAATGTTGAATGCGTAA

Upstream 100 bases:

>100_bases
GATTATTAAATTGATGCCACTCTTTTGAGTGGTTTTCGTTTTTTATTGACTTAATTCATAATTTTCTATAAAATAGTACG
GTAGCTGAAAGGAGAATTAT

Downstream 100 bases:

>100_bases
TTTGTATGATAATCTTATAAATAGAAAAGAAAAAGTAAGCTTTCATATGCCTGGTCATAAGGGCAAGATGTTGGAAGGAA
TGAACGATTTTCTTGAAAAT

Product: arylsulfatase regulator

Products: NA

Alternate protein names: AnSME; Cys-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MIHKYKMNGHNIVLDVNGGSVHVFDDISYDVLDYYKDLSADEIVEKLAQYPEESVRDSIKEIAELEKANMLFSSDDYLHI
EDFKKREPVLKAMCLHVVHDCNLKCEYCFASQGDFGGHKAYMTEEVGKKALKYLVDNSGSRKFLEVDFFGGEPLMDFELV
KKLVKYGNEIAEEKGKKFRFTITTNGVLLDDDKIDFINKNMHNVVLSLDGRKSVNDNMRKTLNDKGSYDLIVPKFQKLIK
GRKGKYYYVRGTFTKKNLDFSEDVKHFKDLGFELSSIEPVVDSDYDDYAITKEDLDTVLNEYEKLAVEYAKDQVNGSNFK
FFHFMVDLTQGPCVIKRMQGCGAGCEYVAVTPEGDIYPCHQFVGNEKFKMGNILDENLTLPEDMREEFLNCHVFTKEDCK
NCWCKFYCSGGCHANAYNFNNDIYKPYELGCAMQKKRTECAIMVEVEKMLNA

Sequences:

>Translated_452_residues
MIHKYKMNGHNIVLDVNGGSVHVFDDISYDVLDYYKDLSADEIVEKLAQYPEESVRDSIKEIAELEKANMLFSSDDYLHI
EDFKKREPVLKAMCLHVVHDCNLKCEYCFASQGDFGGHKAYMTEEVGKKALKYLVDNSGSRKFLEVDFFGGEPLMDFELV
KKLVKYGNEIAEEKGKKFRFTITTNGVLLDDDKIDFINKNMHNVVLSLDGRKSVNDNMRKTLNDKGSYDLIVPKFQKLIK
GRKGKYYYVRGTFTKKNLDFSEDVKHFKDLGFELSSIEPVVDSDYDDYAITKEDLDTVLNEYEKLAVEYAKDQVNGSNFK
FFHFMVDLTQGPCVIKRMQGCGAGCEYVAVTPEGDIYPCHQFVGNEKFKMGNILDENLTLPEDMREEFLNCHVFTKEDCK
NCWCKFYCSGGCHANAYNFNNDIYKPYELGCAMQKKRTECAIMVEVEKMLNA
>Mature_452_residues
MIHKYKMNGHNIVLDVNGGSVHVFDDISYDVLDYYKDLSADEIVEKLAQYPEESVRDSIKEIAELEKANMLFSSDDYLHI
EDFKKREPVLKAMCLHVVHDCNLKCEYCFASQGDFGGHKAYMTEEVGKKALKYLVDNSGSRKFLEVDFFGGEPLMDFELV
KKLVKYGNEIAEEKGKKFRFTITTNGVLLDDDKIDFINKNMHNVVLSLDGRKSVNDNMRKTLNDKGSYDLIVPKFQKLIK
GRKGKYYYVRGTFTKKNLDFSEDVKHFKDLGFELSSIEPVVDSDYDDYAITKEDLDTVLNEYEKLAVEYAKDQVNGSNFK
FFHFMVDLTQGPCVIKRMQGCGAGCEYVAVTPEGDIYPCHQFVGNEKFKMGNILDENLTLPEDMREEFLNCHVFTKEDCK
NCWCKFYCSGGCHANAYNFNNDIYKPYELGCAMQKKRTECAIMVEVEKMLNA

Specific function: Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reduc

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081923, Length=336, Percent_Identity=24.702380952381, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 52005; Mature: 52005

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHKYKMNGHNIVLDVNGGSVHVFDDISYDVLDYYKDLSADEIVEKLAQYPEESVRDSIK
CCEEEEECCCEEEEEECCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
EIAELEKANMLFSSDDYLHIEDFKKREPVLKAMCLHVVHDCNLKCEYCFASQGDFGGHKA
HHHHHHHHHEEECCCCEEECCCHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
YMTEEVGKKALKYLVDNSGSRKFLEVDFFGGEPLMDFELVKKLVKYGNEIAEEKGKKFRF
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHCCCEEEE
TITTNGVLLDDDKIDFINKNMHNVVLSLDGRKSVNDNMRKTLNDKGSYDLIVPKFQKLIK
EEEECCEEECCCCCHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCEEEECHHHHHHHC
GRKGKYYYVRGTFTKKNLDFSEDVKHFKDLGFELSSIEPVVDSDYDDYAITKEDLDTVLN
CCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCCCEECHHHHHHHHH
EYEKLAVEYAKDQVNGSNFKFFHFMVDLTQGPCVIKRMQGCGAGCEYVAVTPEGDIYPCH
HHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCCEEEECCCCCEEEHH
QFVGNEKFKMGNILDENLTLPEDMREEFLNCHVFTKEDCKNCWCKFYCSGGCHANAYNFN
HHCCCCCEEECCCCCCCCCCCHHHHHHHHCEEEECHHHHHCCEEEEEECCCCCCCCEECC
NDIYKPYELGCAMQKKRTECAIMVEVEKMLNA
CCCCCHHHHCHHHHHCCCCEEEEEEHHHHHCC
>Mature Secondary Structure
MIHKYKMNGHNIVLDVNGGSVHVFDDISYDVLDYYKDLSADEIVEKLAQYPEESVRDSIK
CCEEEEECCCEEEEEECCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHH
EIAELEKANMLFSSDDYLHIEDFKKREPVLKAMCLHVVHDCNLKCEYCFASQGDFGGHKA
HHHHHHHHHEEECCCCEEECCCHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHH
YMTEEVGKKALKYLVDNSGSRKFLEVDFFGGEPLMDFELVKKLVKYGNEIAEEKGKKFRF
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCHHHHHHCCCEEEE
TITTNGVLLDDDKIDFINKNMHNVVLSLDGRKSVNDNMRKTLNDKGSYDLIVPKFQKLIK
EEEECCEEECCCCCHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCEEEECHHHHHHHC
GRKGKYYYVRGTFTKKNLDFSEDVKHFKDLGFELSSIEPVVDSDYDDYAITKEDLDTVLN
CCCCCEEEEEEEEEECCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCCCEECHHHHHHHHH
EYEKLAVEYAKDQVNGSNFKFFHFMVDLTQGPCVIKRMQGCGAGCEYVAVTPEGDIYPCH
HHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCCEEEECCCCCEEEHH
QFVGNEKFKMGNILDENLTLPEDMREEFLNCHVFTKEDCKNCWCKFYCSGGCHANAYNFN
HHCCCCCEEECCCCCCCCCCCHHHHHHHHCEEEECHHHHHCCEEEEEECCCCCCCCEECC
NDIYKPYELGCAMQKKRTECAIMVEVEKMLNA
CCCCCHHHHCHHHHHCCCCEEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA