Click here to switch to the map view.

The map label for this gene is yqgN [H]

Identifier: 169824883

GI number: 169824883

Start: 1291765

End: 1292304

Strand: Direct

Name: yqgN [H]

Synonym: FMG_1186

Alternate gene names: 169824883

Gene position: 1291765-1292304 (Clockwise)

Preceding gene: 169824873

Following gene: 169824908

Centisome position: 71.86

GC content: 32.96

Gene sequence:

>540_bases
ATGAAAATGAATAAAAAAGAAATTAGAAAACAAATGTTACAACAAAGAGACTCCATCTCCGACAAACAAAAAGTCGACGA
TGAACTCTTAAAAGAATTGGAAAACTTAGAAGAATTCAAAAATTCCAAAAATTTTTTTGTGTATGTGAGCTTTGGCTCTG
AGTTTAATACTCACAAACTCATCAAAGATTTGTTGGAACAAGGAAAAAAAGTATACGTTCCTTACGTAAAATCAAAAGGA
CAGATGATTGCCGTAGAAATCAAAAGCATGGATGATTTGGCTCCTGGAGCTTACGGAATCTTAGAACCTAAAAATCCAGT
TGAATCAGACGTTAAATTTGATTTCATGCTAGTACCTGGATTATGCTTCGACAAAAACAAATACAGAATCGGCTACGGTG
GAGGATTTTACGACAGATTCATCGACAAAATCGGCGAAGATTCGTATAAAGTATCCATAGTGTACGATTTTCAATTAGTT
GATGATTTAAATCCAGAAGAGTTTGACAGACCAGTTGACAAATTAATTATTCAAAAATAA

Upstream 100 bases:

>100_bases
TAACATTTTTCACCTCGCAACCCTTATTATATCACAGTATTTTTAAATTTTTAAACAACTGGATATTTAAATCTTTTTAG
GGTATATATATTTTTAGGTG

Downstream 100 bases:

>100_bases
TTATCTACAAGCAAAAAGACCACAAAATTGAATTTCAATTCATGTGGTCTTTATTCGTATAAGTATCGTGGACAAGAACA
TCCAATCAACCAAACTTATA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKMNKKEIRKQMLQQRDSISDKQKVDDELLKELENLEEFKNSKNFFVYVSFGSEFNTHKLIKDLLEQGKKVYVPYVKSKG
QMIAVEIKSMDDLAPGAYGILEPKNPVESDVKFDFMLVPGLCFDKNKYRIGYGGGFYDRFIDKIGEDSYKVSIVYDFQLV
DDLNPEEFDRPVDKLIIQK

Sequences:

>Translated_179_residues
MKMNKKEIRKQMLQQRDSISDKQKVDDELLKELENLEEFKNSKNFFVYVSFGSEFNTHKLIKDLLEQGKKVYVPYVKSKG
QMIAVEIKSMDDLAPGAYGILEPKNPVESDVKFDFMLVPGLCFDKNKYRIGYGGGFYDRFIDKIGEDSYKVSIVYDFQLV
DDLNPEEFDRPVDKLIIQK
>Mature_179_residues
MKMNKKEIRKQMLQQRDSISDKQKVDDELLKELENLEEFKNSKNFFVYVSFGSEFNTHKLIKDLLEQGKKVYVPYVKSKG
QMIAVEIKSMDDLAPGAYGILEPKNPVESDVKFDFMLVPGLCFDKNKYRIGYGGGFYDRFIDKIGEDSYKVSIVYDFQLV
DDLNPEEFDRPVDKLIIQK

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=187, Percent_Identity=24.0641711229947, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1789278, Length=171, Percent_Identity=27.4853801169591, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17510857, Length=192, Percent_Identity=27.6041666666667, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 20890; Mature: 20890

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMNKKEIRKQMLQQRDSISDKQKVDDELLKELENLEEFKNSKNFFVYVSFGSEFNTHKL
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHH
IKDLLEQGKKVYVPYVKSKGQMIAVEIKSMDDLAPGAYGILEPKNPVESDVKFDFMLVPG
HHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
LCFDKNKYRIGYGGGFYDRFIDKIGEDSYKVSIVYDFQLVDDLNPEEFDRPVDKLIIQK
EEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHCHHHHHHCCC
>Mature Secondary Structure
MKMNKKEIRKQMLQQRDSISDKQKVDDELLKELENLEEFKNSKNFFVYVSFGSEFNTHKL
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHH
IKDLLEQGKKVYVPYVKSKGQMIAVEIKSMDDLAPGAYGILEPKNPVESDVKFDFMLVPG
HHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECC
LCFDKNKYRIGYGGGFYDRFIDKIGEDSYKVSIVYDFQLVDDLNPEEFDRPVDKLIIQK
EEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]