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The map label for this gene is lytC [H]

Identifier: 169824803

GI number: 169824803

Start: 1199142

End: 1200689

Strand: Direct

Name: lytC [H]

Synonym: FMG_1106

Alternate gene names: 169824803

Gene position: 1199142-1200689 (Clockwise)

Preceding gene: 169824802

Following gene: 169824807

Centisome position: 66.71

GC content: 31.07

Gene sequence:

>1548_bases
ATGAAACACTTTAAAAATTTCAAAATCATCGTTTTGGCATTTATATTAGCACTTTCAATATCAACGACAACATTTGCAAA
AAAACAAATCGAAAAAGTTTCAATCGAAGGTAAAAACAGATACGAAACGGCAATTCAAATATCAAAGATTTCGCATCCTA
AAACCTCAAACACTGTAATAATTGTAAATTCAGAAAAAATCGCAGATTCATTGTCAGTTGGAGTCTTAGCTCACCAAATT
AAAAGTCCTATTCTTTTAACTGATTTTGATAAAATAAATGAATCGACACTAAAAGAAATTCAAAGACTCAAAGCGAAAAA
CATCTTGCTGATAGGTGGAAATCAAAGTATTTCCAAATCACAAGAATCATATCTTATAAAACACAGTTATAATGTAAAAA
GAATTTCTGGAAAAGATAGAATTGATACATCATTTGAAATAGCAAAAGAAATTTCTAATATCAAAAAATCAAAAGAATTC
GACAATGCATTTGTTGTTCACGCCACCAAATCAATCGTAGATTCAGCAAGTGTCAGTGCAGCTGCATGTCGTATGAATAG
TCCAATTTTATTCGTAGGAAATGACACAACATCATTTAACGAAAAATGTGCAAAATATACATTCAAAAACACTTATTTAA
TAGGTGGAGCTACAGCAAAATTTTCAAATAGTTTCCCAAATTCGAAAATAGTTTATGGGAAAAACAGAAATGATACAAGC
ATGAAAATAGCATATACTTTCTTCAAAAATTCGAAGTCTGTATTCTTAGCAAAAAACGGAGAACAAATATTTTCTGAATT
GATAGATTGCGTAACAGTAGCACCATTTGCAGCAAATGAAAAATCTCCTATTATATTTGCATCAACAAAAAATAATCTAA
CAAAATCAGAGAAAAGTTTTTATGATAAATTAAACCCAAATAAAATAACATTAATCGGCGGTGGACTTCATCTTAAATTT
GACGAAATAATCGGAAAAACTCCCCCTAAAAAAGATTACGTATTATTAAATGTCCCACAAATCAACCAAAACAAAGCAGG
TTTACCAATGGGATGCGAAGCAGCATCACTACTTCAATGTTTGCACTACAAAAACATAAAAACAAACACGAATATTAACC
AATTTATAAAAGAAATGCCACTTGCAAAAGATAACAATCCAAATCACGGATTTGCAGGCTCTGCTTTTAATATTGACGAA
AAAATATACCAGTCAATATTTCCAGAACCCCTAACAAAATGGGCAAATAGATATTCAAGAGCAGAAAATATTTCGGGAAA
ATCTTCGGAATATATAAGAGAAGAAATCGCAAAAGGAAATCCAGTAATATTTTTTGGAACTTATAAATTCAGAAATCCAA
CATTCAAAGATTATTTCTGGGGAAAAAATGCCCTCTACAACGCACACGTAATGGTAGTTGATGGCTACGATAAAAATAGA
ATGCACATCGTAGATCCCGCAGAAGATAAACCAAACGGATATTGGATATCCCGTTCGCTTTTCGATAAAAGATACAACAT
CAAAAAGTTTGCAGTCGTTGTGAGATAA

Upstream 100 bases:

>100_bases
AATAATTTCAGTATTCTTTCCTCATCTTACAAGAGTATATATTGGATGGAGTGATCTTGAATACATCGGACCTGTTAGAT
CTTTAGGTTAGGAGTTAAAA

Downstream 100 bases:

>100_bases
TTTTATAATAGATACAACAAAAGCCACCATATGGTGGCTTTTTTCATTAGTTTATTTTCCTAATCTCAATAAATTTTATT
CATAGAAAGATTGGAATTGT

Product: putative N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKHFKNFKIIVLAFILALSISTTTFAKKQIEKVSIEGKNRYETAIQISKISHPKTSNTVIIVNSEKIADSLSVGVLAHQI
KSPILLTDFDKINESTLKEIQRLKAKNILLIGGNQSISKSQESYLIKHSYNVKRISGKDRIDTSFEIAKEISNIKKSKEF
DNAFVVHATKSIVDSASVSAAACRMNSPILFVGNDTTSFNEKCAKYTFKNTYLIGGATAKFSNSFPNSKIVYGKNRNDTS
MKIAYTFFKNSKSVFLAKNGEQIFSELIDCVTVAPFAANEKSPIIFASTKNNLTKSEKSFYDKLNPNKITLIGGGLHLKF
DEIIGKTPPKKDYVLLNVPQINQNKAGLPMGCEAASLLQCLHYKNIKTNTNINQFIKEMPLAKDNNPNHGFAGSAFNIDE
KIYQSIFPEPLTKWANRYSRAENISGKSSEYIREEIAKGNPVIFFGTYKFRNPTFKDYFWGKNALYNAHVMVVDGYDKNR
MHIVDPAEDKPNGYWISRSLFDKRYNIKKFAVVVR

Sequences:

>Translated_515_residues
MKHFKNFKIIVLAFILALSISTTTFAKKQIEKVSIEGKNRYETAIQISKISHPKTSNTVIIVNSEKIADSLSVGVLAHQI
KSPILLTDFDKINESTLKEIQRLKAKNILLIGGNQSISKSQESYLIKHSYNVKRISGKDRIDTSFEIAKEISNIKKSKEF
DNAFVVHATKSIVDSASVSAAACRMNSPILFVGNDTTSFNEKCAKYTFKNTYLIGGATAKFSNSFPNSKIVYGKNRNDTS
MKIAYTFFKNSKSVFLAKNGEQIFSELIDCVTVAPFAANEKSPIIFASTKNNLTKSEKSFYDKLNPNKITLIGGGLHLKF
DEIIGKTPPKKDYVLLNVPQINQNKAGLPMGCEAASLLQCLHYKNIKTNTNINQFIKEMPLAKDNNPNHGFAGSAFNIDE
KIYQSIFPEPLTKWANRYSRAENISGKSSEYIREEIAKGNPVIFFGTYKFRNPTFKDYFWGKNALYNAHVMVVDGYDKNR
MHIVDPAEDKPNGYWISRSLFDKRYNIKKFAVVVR
>Mature_515_residues
MKHFKNFKIIVLAFILALSISTTTFAKKQIEKVSIEGKNRYETAIQISKISHPKTSNTVIIVNSEKIADSLSVGVLAHQI
KSPILLTDFDKINESTLKEIQRLKAKNILLIGGNQSISKSQESYLIKHSYNVKRISGKDRIDTSFEIAKEISNIKKSKEF
DNAFVVHATKSIVDSASVSAAACRMNSPILFVGNDTTSFNEKCAKYTFKNTYLIGGATAKFSNSFPNSKIVYGKNRNDTS
MKIAYTFFKNSKSVFLAKNGEQIFSELIDCVTVAPFAANEKSPIIFASTKNNLTKSEKSFYDKLNPNKITLIGGGLHLKF
DEIIGKTPPKKDYVLLNVPQINQNKAGLPMGCEAASLLQCLHYKNIKTNTNINQFIKEMPLAKDNNPNHGFAGSAFNIDE
KIYQSIFPEPLTKWANRYSRAENISGKSSEYIREEIAKGNPVIFFGTYKFRNPTFKDYFWGKNALYNAHVMVVDGYDKNR
MHIVDPAEDKPNGYWISRSLFDKRYNIKKFAVVVR

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich

COG id: COG2247

COG function: function code M; Putative cell wall-binding domain

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007253
- InterPro:   IPR002508 [H]

Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 57993; Mature: 57993

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFKNFKIIVLAFILALSISTTTFAKKQIEKVSIEGKNRYETAIQISKISHPKTSNTVI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCEEEEEEEEECCCCCCCCEEE
IVNSEKIADSLSVGVLAHQIKSPILLTDFDKINESTLKEIQRLKAKNILLIGGNQSISKS
EEECHHHHHHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHHHHHCCEEEECCCCCCCCC
QESYLIKHSYNVKRISGKDRIDTSFEIAKEISNIKKSKEFDNAFVVHATKSIVDSASVSA
CCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCH
AACRMNSPILFVGNDTTSFNEKCAKYTFKNTYLIGGATAKFSNSFPNSKIVYGKNRNDTS
HHHCCCCCEEEECCCCCCHHHHHHHEEECCEEEEECCCHHCCCCCCCCEEEECCCCCCCE
MKIAYTFFKNSKSVFLAKNGEQIFSELIDCVTVAPFAANEKSPIIFASTKNNLTKSEKSF
EEEEEEEECCCCEEEEECCHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCHHHHHH
YDKLNPNKITLIGGGLHLKFDEIIGKTPPKKDYVLLNVPQINQNKAGLPMGCEAASLLQC
HHCCCCCEEEEEECCEEEEEHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
LHYKNIKTNTNINQFIKEMPLAKDNNPNHGFAGSAFNIDEKIYQSIFPEPLTKWANRYSR
HHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
AENISGKSSEYIREEIAKGNPVIFFGTYKFRNPTFKDYFWGKNALYNAHVMVVDGYDKNR
HHCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCHHCCCCCCEEEEEEEEEECCCCCC
MHIVDPAEDKPNGYWISRSLFDKRYNIKKFAVVVR
EEEECCCCCCCCCEEEEHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MKHFKNFKIIVLAFILALSISTTTFAKKQIEKVSIEGKNRYETAIQISKISHPKTSNTVI
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCEEEEEEEEECCCCCCCCEEE
IVNSEKIADSLSVGVLAHQIKSPILLTDFDKINESTLKEIQRLKAKNILLIGGNQSISKS
EEECHHHHHHHHHHHHHHHHCCCEEEECHHHCCHHHHHHHHHHHHCCEEEECCCCCCCCC
QESYLIKHSYNVKRISGKDRIDTSFEIAKEISNIKKSKEFDNAFVVHATKSIVDSASVSA
CCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCH
AACRMNSPILFVGNDTTSFNEKCAKYTFKNTYLIGGATAKFSNSFPNSKIVYGKNRNDTS
HHHCCCCCEEEECCCCCCHHHHHHHEEECCEEEEECCCHHCCCCCCCCEEEECCCCCCCE
MKIAYTFFKNSKSVFLAKNGEQIFSELIDCVTVAPFAANEKSPIIFASTKNNLTKSEKSF
EEEEEEEECCCCEEEEECCHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCHHHHHH
YDKLNPNKITLIGGGLHLKFDEIIGKTPPKKDYVLLNVPQINQNKAGLPMGCEAASLLQC
HHCCCCCEEEEEECCEEEEEHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
LHYKNIKTNTNINQFIKEMPLAKDNNPNHGFAGSAFNIDEKIYQSIFPEPLTKWANRYSR
HHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHH
AENISGKSSEYIREEIAKGNPVIFFGTYKFRNPTFKDYFWGKNALYNAHVMVVDGYDKNR
HHCCCCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCHHCCCCCCEEEEEEEEEECCCCCC
MHIVDPAEDKPNGYWISRSLFDKRYNIKKFAVVVR
EEEECCCCCCCCCEEEEHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1357079; 1682302; 9384377 [H]