Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 169824516

GI number: 169824516

Start: 889757

End: 890476

Strand: Direct

Name: ycbL [H]

Synonym: FMG_0819

Alternate gene names: 169824516

Gene position: 889757-890476 (Clockwise)

Preceding gene: 169824515

Following gene: 169824517

Centisome position: 49.5

GC content: 27.36

Gene sequence:

>720_bases
TTGTTTAAAGAAAACATAACAGATATTAAAATTTTAATAGTAGAAGATGAAAAAAATATCTCTAATGCTGAAAAAAAATA
CTTAGAAGTTGAAGGTTTTAGAGTTGAACAAGCTTTTGATGGACAAGAAGCCATCGATATGATTAATTCAACAGATTATT
CGATGATTATTTTGGATTTGATGCTTCCTAAAATAAGTGGGGAAAAAGTTATGGAAGTTATTAGGTCCCGAACAGAAACT
CCTGTTATAATGGTTACTGCGAAAATAGATGAAGATGAAATATTAGAAGGATTAAAGCTTGGAGCTGACGATTATATAAC
TAAACCTTTTAGTTTAAAAATTTTAGTACAAAAAGTAAAAACAATCTTGAGGAGAGTTGAAAAACTTGGCCTACCTAAAT
CAGATAAGATTTATTTTGATAATGGACGAGTTAGTATTTCTTTTGATGATAATACTTTTATTAAAGATGGAGAAAGTATT
AGTCTTACAAGTAATGAATTTCAAATAATCAAAACTTTATTTTCGAATCCTAACAAAATTTTTACTAGAGATGAAATAAT
AGAATTATCTTTTGGATATGATTATGAAGCTTTTGACCGAGCTATTGATACTCATATAAAAAACATTAGGCATAAAATTG
AAGATAATCCTAAAAAACCTCGATATATAAAAACTATATATGGTGTAGGCTACAAATTGGGTGTTTACGATGAAGCTTAA

Upstream 100 bases:

>100_bases
GGAACACCAGAAGATATAGCAAATTTAGTGGAATTTTTAATATCCGATAAAAATTCATTTATGACTGGACAAATATTAAG
TCCAAATGGAGGTTTTGTAA

Downstream 100 bases:

>100_bases
ATCTGAAATTTTGTATGAATTTTTAAGAGCTATTCTATTTCCTATTTTATTATTATCATTTATTGCTGTTTTTGTTTTTC
AATTTTCATTTAAAAATTTT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MFKENITDIKILIVEDEKNISNAEKKYLEVEGFRVEQAFDGQEAIDMINSTDYSMIILDLMLPKISGEKVMEVIRSRTET
PVIMVTAKIDEDEILEGLKLGADDYITKPFSLKILVQKVKTILRRVEKLGLPKSDKIYFDNGRVSISFDDNTFIKDGESI
SLTSNEFQIIKTLFSNPNKIFTRDEIIELSFGYDYEAFDRAIDTHIKNIRHKIEDNPKKPRYIKTIYGVGYKLGVYDEA

Sequences:

>Translated_239_residues
MFKENITDIKILIVEDEKNISNAEKKYLEVEGFRVEQAFDGQEAIDMINSTDYSMIILDLMLPKISGEKVMEVIRSRTET
PVIMVTAKIDEDEILEGLKLGADDYITKPFSLKILVQKVKTILRRVEKLGLPKSDKIYFDNGRVSISFDDNTFIKDGESI
SLTSNEFQIIKTLFSNPNKIFTRDEIIELSFGYDYEAFDRAIDTHIKNIRHKIEDNPKKPRYIKTIYGVGYKLGVYDEA
>Mature_239_residues
MFKENITDIKILIVEDEKNISNAEKKYLEVEGFRVEQAFDGQEAIDMINSTDYSMIILDLMLPKISGEKVMEVIRSRTET
PVIMVTAKIDEDEILEGLKLGADDYITKPFSLKILVQKVKTILRRVEKLGLPKSDKIYFDNGRVSISFDDNTFIKDGESI
SLTSNEFQIIKTLFSNPNKIFTRDEIIELSFGYDYEAFDRAIDTHIKNIRHKIEDNPKKPRYIKTIYGVGYKLGVYDEA

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=34.2222222222222, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=37.719298245614, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=34.9137931034483, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=30.3964757709251, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=33.4782608695652, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.4782608695652, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=31.6964285714286, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=29.5154185022026, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=28.8288288288288, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=28.82096069869, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=29.2035398230088, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=25.5411255411255, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=29.4372294372294, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=32.4561403508772, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788191, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=31.6831683168317, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=128, Percent_Identity=35.15625, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27569; Mature: 27569

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKENITDIKILIVEDEKNISNAEKKYLEVEGFRVEQAFDGQEAIDMINSTDYSMIILDL
CCCCCCCEEEEEEEECCCCCCHHHHHEEEECCEEEECCCCCHHHHHHHCCCCHHEEEEEH
MLPKISGEKVMEVIRSRTETPVIMVTAKIDEDEILEGLKLGADDYITKPFSLKILVQKVK
HCCCCCCHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCHHCCCCHHHHHHHHHHH
TILRRVEKLGLPKSDKIYFDNGRVSISFDDNTFIKDGESISLTSNEFQIIKTLFSNPNKI
HHHHHHHHHCCCCCCEEEEECCEEEEEECCCCEEECCCEEEEECCHHHHHHHHHCCCCEE
FTRDEIIELSFGYDYEAFDRAIDTHIKNIRHKIEDNPKKPRYIKTIYGVGYKLGVYDEA
EECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEEECCCC
>Mature Secondary Structure
MFKENITDIKILIVEDEKNISNAEKKYLEVEGFRVEQAFDGQEAIDMINSTDYSMIILDL
CCCCCCCEEEEEEEECCCCCCHHHHHEEEECCEEEECCCCCHHHHHHHCCCCHHEEEEEH
MLPKISGEKVMEVIRSRTETPVIMVTAKIDEDEILEGLKLGADDYITKPFSLKILVQKVK
HCCCCCCHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCHHCCCCHHHHHHHHHHH
TILRRVEKLGLPKSDKIYFDNGRVSISFDDNTFIKDGESISLTSNEFQIIKTLFSNPNKI
HHHHHHHHHCCCCCCEEEEECCEEEEEECCCCEEECCCEEEEECCHHHHHHHHHCCCCEE
FTRDEIIELSFGYDYEAFDRAIDTHIKNIRHKIEDNPKKPRYIKTIYGVGYKLGVYDEA
EECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]