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The map label for this gene is femX [H]

Identifier: 169824498

GI number: 169824498

Start: 871333

End: 872562

Strand: Direct

Name: femX [H]

Synonym: FMG_0801

Alternate gene names: 169824498

Gene position: 871333-872562 (Clockwise)

Preceding gene: 169824497

Following gene: 169824515

Centisome position: 48.47

GC content: 28.21

Gene sequence:

>1230_bases
ATGGCTTACGAAATGGTTACACTAAGTGCTGAAGAACATGATAATTTTGTTAAAAACCATAAATACGGAGAATTAAATCA
AATATATAAATGGCAATATGTAAAAAAAGGATGGATTGGAAAGAATATAGGAGTTAAAAAAGACGACAAACTTATTGGAG
CTTGTTTGATTTTATTAAAAAAGCTTCCTATTCTTCCCTATTATTTTGCTTATGCACCTAAAGGGCCAGTAGTTGATTAT
GAAAATAAAGAAGATTTAAAAGCTACTATCCAAATTTTAAAAGATTTTTGCAAGAAAAATAAAGTTTTCTCTTTAAAGTT
TGACCCTCAAGTATCTGTAGAAATTGATGGATTAATTAGTTACTTAAAAAATCTGGGATGTTACCATCACGGATTAAAAA
AAGGATTAGAATATAATCAACCTAGATATTATATGATAACTGATATAAACAAATCAGAGAAAGATGTGATGAATTCGTTT
CAATCTAGAACAAAAAGTGTTGTAAAAAAATCTTTAAAAAACGGCCTTGAATGTCAACGATGTGATAAGAGTGAGTTACC
AAAGTTTTCAAAATTGATGGAAATAACATCAAAAAGAGACGAATTCAATCATCGAAGTCATGAATATTTTGAGAATTTAT
ATGATGTTTTAGGACCAGATGATGATTGTGAATTATATCTAACTAAACTTATACCATCTCTTGTAAAGAAATCCAATGAA
GAAGAATTAAATCAAATAGATAATCAAGAGTTGAAAACTAAAAACAAATTAGAAAAAGATATAACAGAAGATAAAAAGAA
TAACTTCTTAAAAGAATTAGATGTTTTAGACAACAGAAGAAAAAGATGTAAAGATTTGATTGAGCAAATGAATGAATACA
TTCAAAATGGTGTTGATGAAATTGTATTATCCGGTGCCTTACTAACTTTTTGTGGCAAAAAATCATATTATCTTTATGGT
GCATCTTCTAATGATTTCAGAGACTTAAGTCCAAACTACTTAATGCAATGGACTATGATGAAAAGGGCTATAGAAAAAGG
ATGCACGACTTATGACTTTGGTGGCGTATCTGGTTATACGCCTGAAGATAATGTAGAAGATCATGAAGCAGGATTATATG
AATTTAAAAAAAGATTTGGAACAGAAATGCTTGCTACAATTGGTGAGTTTGACATAGTTTTTAATAAACTCATTAATAAA
TTATTTGAATTTGCATTGAAACACAGATAA

Upstream 100 bases:

>100_bases
TGATAGAGTAAATTCGTTTACTCTATCTTTTTTTGCTTTTAAAAGAAATTATTATTAAGTAGTTTTATGGTATAATGAAT
AAAGTTAAGGAAGTGATAAA

Downstream 100 bases:

>100_bases
TAAAAAACCTAGAATTGATGATGAAATCAATCCTAGGTTTTTTTAATCTAATAAATATTTTAATTTATTTTTATAAACTC
TTGTGTAGAATATGATAAAC

Product: putative anti resistance factor

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAYEMVTLSAEEHDNFVKNHKYGELNQIYKWQYVKKGWIGKNIGVKKDDKLIGACLILLKKLPILPYYFAYAPKGPVVDY
ENKEDLKATIQILKDFCKKNKVFSLKFDPQVSVEIDGLISYLKNLGCYHHGLKKGLEYNQPRYYMITDINKSEKDVMNSF
QSRTKSVVKKSLKNGLECQRCDKSELPKFSKLMEITSKRDEFNHRSHEYFENLYDVLGPDDDCELYLTKLIPSLVKKSNE
EELNQIDNQELKTKNKLEKDITEDKKNNFLKELDVLDNRRKRCKDLIEQMNEYIQNGVDEIVLSGALLTFCGKKSYYLYG
ASSNDFRDLSPNYLMQWTMMKRAIEKGCTTYDFGGVSGYTPEDNVEDHEAGLYEFKKRFGTEMLATIGEFDIVFNKLINK
LFEFALKHR

Sequences:

>Translated_409_residues
MAYEMVTLSAEEHDNFVKNHKYGELNQIYKWQYVKKGWIGKNIGVKKDDKLIGACLILLKKLPILPYYFAYAPKGPVVDY
ENKEDLKATIQILKDFCKKNKVFSLKFDPQVSVEIDGLISYLKNLGCYHHGLKKGLEYNQPRYYMITDINKSEKDVMNSF
QSRTKSVVKKSLKNGLECQRCDKSELPKFSKLMEITSKRDEFNHRSHEYFENLYDVLGPDDDCELYLTKLIPSLVKKSNE
EELNQIDNQELKTKNKLEKDITEDKKNNFLKELDVLDNRRKRCKDLIEQMNEYIQNGVDEIVLSGALLTFCGKKSYYLYG
ASSNDFRDLSPNYLMQWTMMKRAIEKGCTTYDFGGVSGYTPEDNVEDHEAGLYEFKKRFGTEMLATIGEFDIVFNKLINK
LFEFALKHR
>Mature_408_residues
AYEMVTLSAEEHDNFVKNHKYGELNQIYKWQYVKKGWIGKNIGVKKDDKLIGACLILLKKLPILPYYFAYAPKGPVVDYE
NKEDLKATIQILKDFCKKNKVFSLKFDPQVSVEIDGLISYLKNLGCYHHGLKKGLEYNQPRYYMITDINKSEKDVMNSFQ
SRTKSVVKKSLKNGLECQRCDKSELPKFSKLMEITSKRDEFNHRSHEYFENLYDVLGPDDDCELYLTKLIPSLVKKSNEE
ELNQIDNQELKTKNKLEKDITEDKKNNFLKELDVLDNRRKRCKDLIEQMNEYIQNGVDEIVLSGALLTFCGKKSYYLYGA
SSNDFRDLSPNYLMQWTMMKRAIEKGCTTYDFGGVSGYTPEDNVEDHEAGLYEFKKRFGTEMLATIGEFDIVFNKLINKL
FEFALKHR

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 47783; Mature: 47652

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEMVTLSAEEHDNFVKNHKYGELNQIYKWQYVKKGWIGKNIGVKKDDKLIGACLILLK
CCCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
KLPILPYYFAYAPKGPVVDYENKEDLKATIQILKDFCKKNKVFSLKFDPQVSVEIDGLIS
HCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHH
YLKNLGCYHHGLKKGLEYNQPRYYMITDINKSEKDVMNSFQSRTKSVVKKSLKNGLECQR
HHHHCCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
CDKSELPKFSKLMEITSKRDEFNHRSHEYFENLYDVLGPDDDCELYLTKLIPSLVKKSNE
CCHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCH
EELNQIDNQELKTKNKLEKDITEDKKNNFLKELDVLDNRRKRCKDLIEQMNEYIQNGVDE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLSGALLTFCGKKSYYLYGASSNDFRDLSPNYLMQWTMMKRAIEKGCTTYDFGGVSGYT
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
PEDNVEDHEAGLYEFKKRFGTEMLATIGEFDIVFNKLINKLFEFALKHR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYEMVTLSAEEHDNFVKNHKYGELNQIYKWQYVKKGWIGKNIGVKKDDKLIGACLILLK
CCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
KLPILPYYFAYAPKGPVVDYENKEDLKATIQILKDFCKKNKVFSLKFDPQVSVEIDGLIS
HCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHH
YLKNLGCYHHGLKKGLEYNQPRYYMITDINKSEKDVMNSFQSRTKSVVKKSLKNGLECQR
HHHHCCHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
CDKSELPKFSKLMEITSKRDEFNHRSHEYFENLYDVLGPDDDCELYLTKLIPSLVKKSNE
CCHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCH
EELNQIDNQELKTKNKLEKDITEDKKNNFLKELDVLDNRRKRCKDLIEQMNEYIQNGVDE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLSGALLTFCGKKSYYLYGASSNDFRDLSPNYLMQWTMMKRAIEKGCTTYDFGGVSGYT
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCC
PEDNVEDHEAGLYEFKKRFGTEMLATIGEFDIVFNKLINKLFEFALKHR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA