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The map label for this gene is murG

Identifier: 169824314

GI number: 169824314

Start: 681315

End: 682427

Strand: Direct

Name: murG

Synonym: FMG_0617

Alternate gene names: 169824314

Gene position: 681315-682427 (Clockwise)

Preceding gene: 169824313

Following gene: 169824315

Centisome position: 37.9

GC content: 29.56

Gene sequence:

>1113_bases
ATGAATATCATAGTATCTGGCGGTGGAACTGGTGGACATATATATCCAGCAATTTCATTAATAGAAGAATTAAAGAAAAG
AGATAAGGATAATAAAATCCTATATGTAGGCACCGAAAAGGGATTGGAAAGTAGCATTGTACCAAAACTAGGAATAGATT
TTAAAACTATACATGTGAGAGGAATTCCTAGAAAAATAAATGCGAATTCTTTTAAAGCTTTGAAAGAATTATTTCAAGGA
TTAAGAGAAGCAAATAAAATCCTCAAAGAATTCAAACCAGATCTTGTCATAGGAACTGGTGGATATGTGAGTGGACCTAT
ATTATACAAAGCCACTAAAACTAAAGCAAAGGTAGCTTTTCATGAGCAAAATAGTTTTCCGGGAATAACGAATAGAATTC
TATCTAGATATGTTGATAAATATTTTGTGACATTTAAAGAATCGATTAAATATTTCAAAAATCAAGATAAAGCTGTCGTA
ACAGGAAATCCAATTAGAAATAGATTTACTGATATTGAAAAAAACAAAAAATCTGCGCTCGAACAATACGATATTTCAGA
AAATAAAAAGGTTGTATTTATTTTTGGCGGTTCAAATGGTTCTGAAATATTAAACAAAGCAACATTGAATATGATTGAAA
AAATATCTAATCAAGATAAATTCGAAATAGTTTTAGCTACAGGTAAGTTGAACTACGATGAATTTATACAACAATCAGGG
AAAGAAATTAAAAATTTACACGTTTACCCATATATCGATGATATAGATAAAGCTTATGCAGTATCTGATTTAATAGTGAC
AAGTAGTGGAGCTATAACATTAGCTGAATTATCTTTCCTGGGAAAAGCATCTATACTCGTTCCAAAAGCATATACAACTG
AAAATCATCAAGAGCATAACGCCAGAGCTTTTGAAAAAAATGGAGCAAGTAAAGTAATATTAGAAAAAGATTTGAACTCT
GATACATTGTTTGATCAAATTAACGAAATATTAAGTGATGATAATTTATTAAATGAACTTTCAGAAAACTCTAAGAAAAT
GTCATATCCAACTGCTTGTAAAGATATCGTAGATGAACTTTACAGATTGGTAGAACAAGATGAAAAAGCTTAG

Upstream 100 bases:

>100_bases
CCTTACCATTTATTTCTTATGGTGGAACGTCTTTGATGATTATGTTGGGTTTGGTTGGAATAATCTTAAATGTAGACAGG
AACAATGAAGAGGAGAGAAA

Downstream 100 bases:

>100_bases
AACGGTTATTATTGTCGCAATATCACTATTGATTGCGCTGATAGTGTATTTATGTGCTACAATTGACTATTTTTCAATAA
AAACAATAAAGGTTAAAAAC

Product: UDP-N-acetylglucosamine--N-acetylmuramyl pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNIIVSGGGTGGHIYPAISLIEELKKRDKDNKILYVGTEKGLESSIVPKLGIDFKTIHVRGIPRKINANSFKALKELFQG
LREANKILKEFKPDLVIGTGGYVSGPILYKATKTKAKVAFHEQNSFPGITNRILSRYVDKYFVTFKESIKYFKNQDKAVV
TGNPIRNRFTDIEKNKKSALEQYDISENKKVVFIFGGSNGSEILNKATLNMIEKISNQDKFEIVLATGKLNYDEFIQQSG
KEIKNLHVYPYIDDIDKAYAVSDLIVTSSGAITLAELSFLGKASILVPKAYTTENHQEHNARAFEKNGASKVILEKDLNS
DTLFDQINEILSDDNLLNELSENSKKMSYPTACKDIVDELYRLVEQDEKA

Sequences:

>Translated_370_residues
MNIIVSGGGTGGHIYPAISLIEELKKRDKDNKILYVGTEKGLESSIVPKLGIDFKTIHVRGIPRKINANSFKALKELFQG
LREANKILKEFKPDLVIGTGGYVSGPILYKATKTKAKVAFHEQNSFPGITNRILSRYVDKYFVTFKESIKYFKNQDKAVV
TGNPIRNRFTDIEKNKKSALEQYDISENKKVVFIFGGSNGSEILNKATLNMIEKISNQDKFEIVLATGKLNYDEFIQQSG
KEIKNLHVYPYIDDIDKAYAVSDLIVTSSGAITLAELSFLGKASILVPKAYTTENHQEHNARAFEKNGASKVILEKDLNS
DTLFDQINEILSDDNLLNELSENSKKMSYPTACKDIVDELYRLVEQDEKA
>Mature_370_residues
MNIIVSGGGTGGHIYPAISLIEELKKRDKDNKILYVGTEKGLESSIVPKLGIDFKTIHVRGIPRKINANSFKALKELFQG
LREANKILKEFKPDLVIGTGGYVSGPILYKATKTKAKVAFHEQNSFPGITNRILSRYVDKYFVTFKESIKYFKNQDKAVV
TGNPIRNRFTDIEKNKKSALEQYDISENKKVVFIFGGSNGSEILNKATLNMIEKISNQDKFEIVLATGKLNYDEFIQQSG
KEIKNLHVYPYIDDIDKAYAVSDLIVTSSGAITLAELSFLGKASILVPKAYTTENHQEHNARAFEKNGASKVILEKDLNS
DTLFDQINEILSDDNLLNELSENSKKMSYPTACKDIVDELYRLVEQDEKA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=367, Percent_Identity=31.0626702997275, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_FINM2 (B0S0Z5)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001691925.1
- ProteinModelPortal:   B0S0Z5
- SMR:   B0S0Z5
- GeneID:   6019491
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0617
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- BioCyc:   FMAG334413:FMG_0617-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41521; Mature: 41521

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIVSGGGTGGHIYPAISLIEELKKRDKDNKILYVGTEKGLESSIVPKLGIDFKTIHVR
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEE
GIPRKINANSFKALKELFQGLREANKILKEFKPDLVIGTGGYVSGPILYKATKTKAKVAF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCEEEEE
HEQNSFPGITNRILSRYVDKYFVTFKESIKYFKNQDKAVVTGNPIRNRFTDIEKNKKSAL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
EQYDISENKKVVFIFGGSNGSEILNKATLNMIEKISNQDKFEIVLATGKLNYDEFIQQSG
HHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCC
KEIKNLHVYPYIDDIDKAYAVSDLIVTSSGAITLAELSFLGKASILVPKAYTTENHQEHN
CHHHCEEEECCHHHHHHHHHHHHHEEECCCCEEEEHHHHHCCCEEEECCCCCCCCCCHHC
ARAFEKNGASKVILEKDLNSDTLFDQINEILSDDNLLNELSENSKKMSYPTACKDIVDEL
CHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
YRLVEQDEKA
HHHHHHCCCC
>Mature Secondary Structure
MNIIVSGGGTGGHIYPAISLIEELKKRDKDNKILYVGTEKGLESSIVPKLGIDFKTIHVR
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEE
GIPRKINANSFKALKELFQGLREANKILKEFKPDLVIGTGGYVSGPILYKATKTKAKVAF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCEEEEE
HEQNSFPGITNRILSRYVDKYFVTFKESIKYFKNQDKAVVTGNPIRNRFTDIEKNKKSAL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
EQYDISENKKVVFIFGGSNGSEILNKATLNMIEKISNQDKFEIVLATGKLNYDEFIQQSG
HHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCC
KEIKNLHVYPYIDDIDKAYAVSDLIVTSSGAITLAELSFLGKASILVPKAYTTENHQEHN
CHHHCEEEECCHHHHHHHHHHHHHEEECCCCEEEEHHHHHCCCEEEECCCCCCCCCCHHC
ARAFEKNGASKVILEKDLNSDTLFDQINEILSDDNLLNELSENSKKMSYPTACKDIVDEL
CHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
YRLVEQDEKA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA