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The map label for this gene is mraY [H]

Identifier: 169824311

GI number: 169824311

Start: 677909

End: 678871

Strand: Direct

Name: mraY [H]

Synonym: FMG_0614

Alternate gene names: 169824311

Gene position: 677909-678871 (Clockwise)

Preceding gene: 169824310

Following gene: 169824312

Centisome position: 37.71

GC content: 29.28

Gene sequence:

>963_bases
ATGAATTTTAAAAGCGAAATTTTAATGTCGATGTTATTAGCGATTATAATTTCATTGATATTGGGAAAGTTTATAATCAA
GATTTTGAGAAAAAAACATATTGGTCAAGAAATCAGAGATGATGGGCCCAAATCACATTATTCAAAAGCCGGTACACCGA
CTATGGGAGGTATTATATTTATAATATCTACATTGATTACTGTGATTGTATTCAGATTGTTTAATAGCGAAGTTTTATTG
GCGATTTATGGAATGATTGCTTTTGGAGCAATTGGTTTTATAGATGACTTTATGAAATTAGTAATGAAGCGTTCATTGGG
ATTAAACGAAAAACAAAAACTTGTATTGCAACTTTTGTTTTCTGTTATTGCTTGCTTCTTAATTAAACAAGTAAATCCTA
ACTTTACAAAACAAGTTATTCCATTTTTCCATAAAACAGTAGATTTTGGTTTAATAACTTACCCATTCTTGATTTTCGTG
ATGATGGGAACATCTAATGCTACTAATCTTACTGATGGATTAGATGGACTTGCAACTTCTGTTTCAATTCCAGTATTCAT
ATCTACAAGTATTATAATGTACAACTTGAATTCTACGGCCAGCATATTCAGTATTATATTTGCAGGAAGTCTGTTGGGAT
TTTTAGTGTACAATTCAAACCCAGCAAAAGTATTTATGGGAGATACTGGATCAATGGCTATTGGCGGAGCATTAGTAATG
ATTATGGCTATGTACGGATTGAGTTTGTATTTAATTATTTTAGGATTTGTTTACATGATTGAAGTATTGTCAGTAATTAT
TCAAATGACAAGCTACAAATTACGAAACAAAAAAAGAGTATTTTTGATGAGTCCAATACATCATCATTATGAATTAAAGG
GATATAAAGAACAAAAAATAGTATCAACTTTTATGGTTGTATCAGTAATTACAAGTTTAATTACATTATTAGATATATTG
TAG

Upstream 100 bases:

>100_bases
AATAAAAAACACTGAATAATAAAATTCTCGTGTGGTATAATAATTACTTATGAGGTATAAAATTGGACATAATTTGTGTT
CATAATTTAAGGAGATAAAT

Downstream 100 bases:

>100_bases
GTGAAATATGAAGAAAATATTAGTATTTGGATTAGCAAGAACCGGAATATCAGCTCTAAAAACATTAAAATTAAAAGGAT
ATAATTTAGGAGCAATCGAT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNFKSEILMSMLLAIIISLILGKFIIKILRKKHIGQEIRDDGPKSHYSKAGTPTMGGIIFIISTLITVIVFRLFNSEVLL
AIYGMIAFGAIGFIDDFMKLVMKRSLGLNEKQKLVLQLLFSVIACFLIKQVNPNFTKQVIPFFHKTVDFGLITYPFLIFV
MMGTSNATNLTDGLDGLATSVSIPVFISTSIIMYNLNSTASIFSIIFAGSLLGFLVYNSNPAKVFMGDTGSMAIGGALVM
IMAMYGLSLYLIILGFVYMIEVLSVIIQMTSYKLRNKKRVFLMSPIHHHYELKGYKEQKIVSTFMVVSVITSLITLLDIL

Sequences:

>Translated_320_residues
MNFKSEILMSMLLAIIISLILGKFIIKILRKKHIGQEIRDDGPKSHYSKAGTPTMGGIIFIISTLITVIVFRLFNSEVLL
AIYGMIAFGAIGFIDDFMKLVMKRSLGLNEKQKLVLQLLFSVIACFLIKQVNPNFTKQVIPFFHKTVDFGLITYPFLIFV
MMGTSNATNLTDGLDGLATSVSIPVFISTSIIMYNLNSTASIFSIIFAGSLLGFLVYNSNPAKVFMGDTGSMAIGGALVM
IMAMYGLSLYLIILGFVYMIEVLSVIIQMTSYKLRNKKRVFLMSPIHHHYELKGYKEQKIVSTFMVVSVITSLITLLDIL
>Mature_320_residues
MNFKSEILMSMLLAIIISLILGKFIIKILRKKHIGQEIRDDGPKSHYSKAGTPTMGGIIFIISTLITVIVFRLFNSEVLL
AIYGMIAFGAIGFIDDFMKLVMKRSLGLNEKQKLVLQLLFSVIACFLIKQVNPNFTKQVIPFFHKTVDFGLITYPFLIFV
MMGTSNATNLTDGLDGLATSVSIPVFISTSIIMYNLNSTASIFSIIFAGSLLGFLVYNSNPAKVFMGDTGSMAIGGALVM
IMAMYGLSLYLIILGFVYMIEVLSVIIQMTSYKLRNKKRVFLMSPIHHHYELKGYKEQKIVSTFMVVSVITSLITLLDIL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=330, Percent_Identity=39.3939393939394, Blast_Score=211, Evalue=6e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35640; Mature: 35640

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKSEILMSMLLAIIISLILGKFIIKILRKKHIGQEIRDDGPKSHYSKAGTPTMGGIIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCCCCCHHHHHH
IISTLITVIVFRLFNSEVLLAIYGMIAFGAIGFIDDFMKLVMKRSLGLNEKQKLVLQLLF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SVIACFLIKQVNPNFTKQVIPFFHKTVDFGLITYPFLIFVMMGTSNATNLTDGLDGLATS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VSIPVFISTSIIMYNLNSTASIFSIIFAGSLLGFLVYNSNPAKVFMGDTGSMAIGGALVM
CCCHHEEECEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHH
IMAMYGLSLYLIILGFVYMIEVLSVIIQMTSYKLRNKKRVFLMSPIHHHYELKGYKEQKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCHHHHH
VSTFMVVSVITSLITLLDIL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFKSEILMSMLLAIIISLILGKFIIKILRKKHIGQEIRDDGPKSHYSKAGTPTMGGIIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHCCCCCCCHHHHHH
IISTLITVIVFRLFNSEVLLAIYGMIAFGAIGFIDDFMKLVMKRSLGLNEKQKLVLQLLF
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
SVIACFLIKQVNPNFTKQVIPFFHKTVDFGLITYPFLIFVMMGTSNATNLTDGLDGLATS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VSIPVFISTSIIMYNLNSTASIFSIIFAGSLLGFLVYNSNPAKVFMGDTGSMAIGGALVM
CCCHHEEECEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHH
IMAMYGLSLYLIILGFVYMIEVLSVIIQMTSYKLRNKKRVFLMSPIHHHYELKGYKEQKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHCCCCHHHHH
VSTFMVVSVITSLITLLDIL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]