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The map label for this gene is rsmH

Identifier: 169824308

GI number: 169824308

Start: 674231

End: 675169

Strand: Direct

Name: rsmH

Synonym: FMG_0611

Alternate gene names: 169824308

Gene position: 674231-675169 (Clockwise)

Preceding gene: 169824307

Following gene: 169824309

Centisome position: 37.51

GC content: 32.06

Gene sequence:

>939_bases
ATGGAATTCAAGCATGTGCCAATTTTATTAAATGAATGCATCGAAAATTTGAATATCAGAGACGGCAAGATTTACGTGGA
TTGCACTGTTGGAGGAGCTGGACATTCCAGAGAAATTGCAAAAAGAATTGGTAATGGAAAGTTGATTTGCTTTGATCAAG
ACGAAGACGCATTAAAAGTTGCGAAACAACGACTAGAAGAATTTGGAGATAAGATTATCTTCATAAAGGATAATTTCAAG
AATATAAAAAATGATTTACATAACTTAGGCATTGAAAAAGTCGATGGAATCCTAATGGATATAGGTGTTAGCTCGTATCA
AATTGATGAAGATAGTAGAGGGTTTTCTTATATGCATGATGCTGATTTGGATATGAGAATGGATCAATCCAATCCAATAA
GTGCAAAAGATATTGTGAACACTTATTCAAAAGAAGACTTGGAAAATGTTATTTTCAAATATTCAGATGAAAAATGGGCC
AAAAGAATTGCTGAATTTATATGTAATGCTAGAGAAACTAAACCAATTAATACTACTTTCGAATTAGTTGAGGTAATTGA
AAAAGCGATTCCTAAAAAGGTTAGAATGAATCAAAAAGGCCACAGCGCTAAGAAAACTTTTCAAGCAATTAGAATTGAAG
TTAACAAAGAATTAGATGTTTTGGAACAGGCTGTAGGAGATTCTATAGATTTATTGAATCCTGAAGGCAGAATTTGCATA
ATAACGTTTCATTCTTTGGAGGATAAAATTTGCAAAGATATTTTCAGACAAAGACAAAAAGGTTGTATATGTCCTCCCGA
AATTCCAGTTTGTGTTTGTAATCATAAACCAGAAATTAAGATTATTACTAGAAAGCCGATAGAGCCTTCAAAAGAAGAAT
TGGAACAAAATTCTAGGGCTAGAAGCGCAAAATTAAGAGTAGCTGAAAAGATTATTTAA

Upstream 100 bases:

>100_bases
ATATGGGATAAAGAGAAATGGGAACAATACTCTAATGATTCTTCACTAAACTATGACGATTTAGCAGATGGTTTAAATGA
TCTTGATTTGTAGGTGAATT

Downstream 100 bases:

>100_bases
TTTGTAGATTATTTGACTGATAAATGGAGACAAAAATGGGTAACGCACAAAGAAAAATCGAAGTATTTCCACAATACGTA
GAAAAAAAAGAATTAGAAAT

Product: S-adenosyl-methyltransferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MEFKHVPILLNECIENLNIRDGKIYVDCTVGGAGHSREIAKRIGNGKLICFDQDEDALKVAKQRLEEFGDKIIFIKDNFK
NIKNDLHNLGIEKVDGILMDIGVSSYQIDEDSRGFSYMHDADLDMRMDQSNPISAKDIVNTYSKEDLENVIFKYSDEKWA
KRIAEFICNARETKPINTTFELVEVIEKAIPKKVRMNQKGHSAKKTFQAIRIEVNKELDVLEQAVGDSIDLLNPEGRICI
ITFHSLEDKICKDIFRQRQKGCICPPEIPVCVCNHKPEIKIITRKPIEPSKEELEQNSRARSAKLRVAEKII

Sequences:

>Translated_312_residues
MEFKHVPILLNECIENLNIRDGKIYVDCTVGGAGHSREIAKRIGNGKLICFDQDEDALKVAKQRLEEFGDKIIFIKDNFK
NIKNDLHNLGIEKVDGILMDIGVSSYQIDEDSRGFSYMHDADLDMRMDQSNPISAKDIVNTYSKEDLENVIFKYSDEKWA
KRIAEFICNARETKPINTTFELVEVIEKAIPKKVRMNQKGHSAKKTFQAIRIEVNKELDVLEQAVGDSIDLLNPEGRICI
ITFHSLEDKICKDIFRQRQKGCICPPEIPVCVCNHKPEIKIITRKPIEPSKEELEQNSRARSAKLRVAEKII
>Mature_312_residues
MEFKHVPILLNECIENLNIRDGKIYVDCTVGGAGHSREIAKRIGNGKLICFDQDEDALKVAKQRLEEFGDKIIFIKDNFK
NIKNDLHNLGIEKVDGILMDIGVSSYQIDEDSRGFSYMHDADLDMRMDQSNPISAKDIVNTYSKEDLENVIFKYSDEKWA
KRIAEFICNARETKPINTTFELVEVIEKAIPKKVRMNQKGHSAKKTFQAIRIEVNKELDVLEQAVGDSIDLLNPEGRICI
ITFHSLEDKICKDIFRQRQKGCICPPEIPVCVCNHKPEIKIITRKPIEPSKEELEQNSRARSAKLRVAEKII

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=336, Percent_Identity=31.8452380952381, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI165377202, Length=187, Percent_Identity=33.1550802139037, Blast_Score=118, Evalue=9e-27,
Organism=Escherichia coli, GI1786270, Length=324, Percent_Identity=39.5061728395062, Blast_Score=224, Evalue=6e-60,
Organism=Drosophila melanogaster, GI62472493, Length=331, Percent_Identity=35.6495468277946, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI28571637, Length=331, Percent_Identity=35.6495468277946, Blast_Score=174, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_FINM2 (B0S0Y9)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001691919.1
- ProteinModelPortal:   B0S0Y9
- SMR:   B0S0Y9
- GeneID:   6019450
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0611
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- BioCyc:   FMAG334413:FMG_0611-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 35717; Mature: 35717

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: BINDING 52-52 BINDING 79-79 BINDING 100-100 BINDING 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKHVPILLNECIENLNIRDGKIYVDCTVGGAGHSREIAKRIGNGKLICFDQDEDALKV
CCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCHHHHH
AKQRLEEFGDKIIFIKDNFKNIKNDLHNLGIEKVDGILMDIGVSSYQIDEDSRGFSYMHD
HHHHHHHHCCEEEEEECCHHHHHHHHHHCCHHHHCCCCEECCCCCEEECCCCCCCCEEEC
ADLDMRMDQSNPISAKDIVNTYSKEDLENVIFKYSDEKWAKRIAEFICNARETKPINTTF
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHH
ELVEVIEKAIPKKVRMNQKGHSAKKTFQAIRIEVNKELDVLEQAVGDSIDLLNPEGRICI
HHHHHHHHHCCHHHHCCCCCCHHHHHHHHHEEEECCHHHHHHHHHCCCEECCCCCCCEEE
ITFHSLEDKICKDIFRQRQKGCICPPEIPVCVCNHKPEIKIITRKPIEPSKEELEQNSRA
EEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHH
RSAKLRVAEKII
HHHHHHHHHHCC
>Mature Secondary Structure
MEFKHVPILLNECIENLNIRDGKIYVDCTVGGAGHSREIAKRIGNGKLICFDQDEDALKV
CCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCHHHHH
AKQRLEEFGDKIIFIKDNFKNIKNDLHNLGIEKVDGILMDIGVSSYQIDEDSRGFSYMHD
HHHHHHHHCCEEEEEECCHHHHHHHHHHCCHHHHCCCCEECCCCCEEECCCCCCCCEEEC
ADLDMRMDQSNPISAKDIVNTYSKEDLENVIFKYSDEKWAKRIAEFICNARETKPINTTF
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHH
ELVEVIEKAIPKKVRMNQKGHSAKKTFQAIRIEVNKELDVLEQAVGDSIDLLNPEGRICI
HHHHHHHHHCCHHHHCCCCCCHHHHHHHHHEEEECCHHHHHHHHHCCCEECCCCCCCEEE
ITFHSLEDKICKDIFRQRQKGCICPPEIPVCVCNHKPEIKIITRKPIEPSKEELEQNSRA
EEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHH
RSAKLRVAEKII
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA