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The map label for this gene is fruK [H]

Identifier: 169823967

GI number: 169823967

Start: 318938

End: 319852

Strand: Direct

Name: fruK [H]

Synonym: FMG_0270

Alternate gene names: 169823967

Gene position: 318938-319852 (Clockwise)

Preceding gene: 169823966

Following gene: 169823968

Centisome position: 17.74

GC content: 32.46

Gene sequence:

>915_bases
ATGATATATACAGTTACAATGAATCCCGCACTTGAATTTGTAAGTGAGGTTACGGATTTTAAATTTGACAAGAACAATAT
ATCTGATTTTGATTTGATGCTACCAGCAGGAAAAGGAATCAATGTTTCAAGGATTCTGAAACAACTTGGTCTTCCAACAG
TTGCAACTGGATTTGCAGGAGGATTTACAGGAGAATTTGTCGAAGACTGGCTAAGAAGAGAAGATATCAAATCTGAATTC
GTAAGAATAGATGACAATACCAGAATCAATATAAAAATCACAGGAACAACGAAAACCGTAATTGAATCCAAAGGACCAAG
CATTTCTCATCAAGAACTACAGGAACTATTATATTATTTATCCAGAGTCAAAGAAGGAGATACTGTATTCTTGTCGACGG
CTTTTCCAAGAAATATTACAGAAACTGTAATCGAAAGAATGATTGCTATCTGCAAGGCCAACAAAGCACAATTCGTACTT
GATATAGACGAGTATTATCTGGAGAAATTTGCAGATGAAGGATCACTTCTTGAAAATATCAGCGTAAAATGCTTGGAACA
TTTATTTAAAACCAAAATAAATTCAGAATCTGATTTGCTTAAATGGAAAAATGAAATATCTAATTTGAATTCAAAATTTG
TCGTAGTTCCATTCGTAGAGAATAAAGTGTATTTGTTTCAAAAAGATTCCACATACGCATTTGAAATAGACGAAATAGCA
AACCAAAAAAGAGATTTTGTTATCGACTCAATAATCGCAGGATTCATCGCTACATTTATCAGAACTTCAGATTATGAAAA
GTCTTTTAAAATGGCAAACGCATGTGCACAAGCTTCGTTGAAGACAAAAGATTTGCCGAAAAAATTTCAAATAGACGACT
GTCTTAAAAACATTAATATAGTAAAAATAGACTAA

Upstream 100 bases:

>100_bases
CTGGAATTATAATAACGAGACTTGTGGTTTTCATGGTCGTTATGACTCTTCTTCAAAAAATATTTTTTGGACTTGCTCCA
GGATTAATGTAGGTGATTAA

Downstream 100 bases:

>100_bases
AATAAAAAAACAAGGTGTTGAATTAAATTCATACCTTGTTTTTTTATGTTGTAATAAATTAAGAAATGGAGATTTAATTG
AAAATGAAAAAGTTTTCAAT

Product: fructose-1-phosphate kinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIYTVTMNPALEFVSEVTDFKFDKNNISDFDLMLPAGKGINVSRILKQLGLPTVATGFAGGFTGEFVEDWLRREDIKSEF
VRIDDNTRINIKITGTTKTVIESKGPSISHQELQELLYYLSRVKEGDTVFLSTAFPRNITETVIERMIAICKANKAQFVL
DIDEYYLEKFADEGSLLENISVKCLEHLFKTKINSESDLLKWKNEISNLNSKFVVVPFVENKVYLFQKDSTYAFEIDEIA
NQKRDFVIDSIIAGFIATFIRTSDYEKSFKMANACAQASLKTKDLPKKFQIDDCLKNINIVKID

Sequences:

>Translated_304_residues
MIYTVTMNPALEFVSEVTDFKFDKNNISDFDLMLPAGKGINVSRILKQLGLPTVATGFAGGFTGEFVEDWLRREDIKSEF
VRIDDNTRINIKITGTTKTVIESKGPSISHQELQELLYYLSRVKEGDTVFLSTAFPRNITETVIERMIAICKANKAQFVL
DIDEYYLEKFADEGSLLENISVKCLEHLFKTKINSESDLLKWKNEISNLNSKFVVVPFVENKVYLFQKDSTYAFEIDEIA
NQKRDFVIDSIIAGFIATFIRTSDYEKSFKMANACAQASLKTKDLPKKFQIDDCLKNINIVKID
>Mature_304_residues
MIYTVTMNPALEFVSEVTDFKFDKNNISDFDLMLPAGKGINVSRILKQLGLPTVATGFAGGFTGEFVEDWLRREDIKSEF
VRIDDNTRINIKITGTTKTVIESKGPSISHQELQELLYYLSRVKEGDTVFLSTAFPRNITETVIERMIAICKANKAQFVL
DIDEYYLEKFADEGSLLENISVKCLEHLFKTKINSESDLLKWKNEISNLNSKFVVVPFVENKVYLFQKDSTYAFEIDEIA
NQKRDFVIDSIIAGFIATFIRTSDYEKSFKMANACAQASLKTKDLPKKFQIDDCLKNINIVKID

Specific function: Key control step of glycolysis. [C]

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

None

Paralogues:

None

Copy number: 496 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 34679; Mature: 34679

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTVTMNPALEFVSEVTDFKFDKNNISDFDLMLPAGKGINVSRILKQLGLPTVATGFAG
CEEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHCCCC
GFTGEFVEDWLRREDIKSEFVRIDDNTRINIKITGTTKTVIESKGPSISHQELQELLYYL
CCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCHHEEHHCCCCCCCHHHHHHHHHHH
SRVKEGDTVFLSTAFPRNITETVIERMIAICKANKAQFVLDIDEYYLEKFADEGSLLENI
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCHHHHHH
SVKCLEHLFKTKINSESDLLKWKNEISNLNSKFVVVPFVENKVYLFQKDSTYAFEIDEIA
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCEEEEHHHHH
NQKRDFVIDSIIAGFIATFIRTSDYEKSFKMANACAQASLKTKDLPKKFQIDDCLKNINI
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEE
VKID
EEEC
>Mature Secondary Structure
MIYTVTMNPALEFVSEVTDFKFDKNNISDFDLMLPAGKGINVSRILKQLGLPTVATGFAG
CEEEEECCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHCCCC
GFTGEFVEDWLRREDIKSEFVRIDDNTRINIKITGTTKTVIESKGPSISHQELQELLYYL
CCCHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCHHEEHHCCCCCCCHHHHHHHHHHH
SRVKEGDTVFLSTAFPRNITETVIERMIAICKANKAQFVLDIDEYYLEKFADEGSLLENI
HHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCHHHHHH
SVKCLEHLFKTKINSESDLLKWKNEISNLNSKFVVVPFVENKVYLFQKDSTYAFEIDEIA
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCEEEEHHHHH
NQKRDFVIDSIIAGFIATFIRTSDYEKSFKMANACAQASLKTKDLPKKFQIDDCLKNINI
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEE
VKID
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]