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The map label for this gene is yciC [H]

Identifier: 169823927

GI number: 169823927

Start: 272922

End: 273800

Strand: Direct

Name: yciC [H]

Synonym: FMG_0230

Alternate gene names: 169823927

Gene position: 272922-273800 (Clockwise)

Preceding gene: 169823926

Following gene: 169823928

Centisome position: 15.18

GC content: 32.54

Gene sequence:

>879_bases
ATGGGTGATAATATGAAGACGATAATAGTGTCAGGATTTTTAGGTTCGGGCAAGACAACATTTATCAATCACATTTTGGG
ATTTAATAAAAACACTCTTGTATTGGAAAATGAATTCGGAGATGTTAGCATAGATTCAATGCTAATCAAAAACGATGATA
TAATTGAAATAAATTCGGGATGTATTTGCTGTGGGCTTAAAAGCGATTTTAAGGAAATTATTCACAAAATCGATAAAGAC
CAATTTGAGTACATAATAATTGAGCCGACAGGGATTGCAAAATTAACCGATATATTGGAAGTTTTGAAAGACGAAGAGAA
TTTACAAATTCAAAAATGCGTGACAATTGTCGATTCTGACAGCTACATTTGTTTTCACGAGGATTTCGGAGAATTTTTCA
ATGATCAAATCAAAAATGCTGATATAATATACATAACGAACATTGAAAATTTGGAAGAAGAAAAAATCGAAGAAGTAAAG
AAATCAATCGAACAATTCAACAAAACTGCGATTATTCACACAGAAGATTTCAGAAACATGAATCCAGATGATATTGTAGC
TGAATTTGAGAATAAAAAAGAACACAAATGTTGTTGTCACGGTCATGGACACAAATGTTGCGGCAAACATCACCACGATC
ACCATGATCATCCTCACGAGGATTCCAAATTCAAGACCAATGTTCAAAAAAATTTAAAATTTGCTTCAAAAGAAGATTTA
GAAAAGTTCTTAGATTCAAAAAGCATTGTTCGAGCCAAAGGAAATGTAGAAATCGCAGACAAGAAAGTTTTCGTGAGCAA
AACTTTGAGTGGGTTGGAAATATCGGATGCAATTTCTGATAGTGAGGATTTTGTGATAATTGAGGTGAATAATGAGTAA

Upstream 100 bases:

>100_bases
AAGTTTTTTATCAATCAATAATACAAAATTCATTTATTTAAATATCCAATAAGTAGTTATTATTTGAACAATACTAACTA
TCAAATATGGTAAAATAAAG

Downstream 100 bases:

>100_bases
AGTTGGAACTTATGATTGTATTATAATGGAAACAACGCCCATTACTAATCCGAAATTATTTGAAGATGCGGACTGTTTGG
TAGAACATTTCAAGGACAAG

Product: putative cobalamin synthesis-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MGDNMKTIIVSGFLGSGKTTFINHILGFNKNTLVLENEFGDVSIDSMLIKNDDIIEINSGCICCGLKSDFKEIIHKIDKD
QFEYIIIEPTGIAKLTDILEVLKDEENLQIQKCVTIVDSDSYICFHEDFGEFFNDQIKNADIIYITNIENLEEEKIEEVK
KSIEQFNKTAIIHTEDFRNMNPDDIVAEFENKKEHKCCCHGHGHKCCGKHHHDHHDHPHEDSKFKTNVQKNLKFASKEDL
EKFLDSKSIVRAKGNVEIADKKVFVSKTLSGLEISDAISDSEDFVIIEVNNE

Sequences:

>Translated_292_residues
MGDNMKTIIVSGFLGSGKTTFINHILGFNKNTLVLENEFGDVSIDSMLIKNDDIIEINSGCICCGLKSDFKEIIHKIDKD
QFEYIIIEPTGIAKLTDILEVLKDEENLQIQKCVTIVDSDSYICFHEDFGEFFNDQIKNADIIYITNIENLEEEKIEEVK
KSIEQFNKTAIIHTEDFRNMNPDDIVAEFENKKEHKCCCHGHGHKCCGKHHHDHHDHPHEDSKFKTNVQKNLKFASKEDL
EKFLDSKSIVRAKGNVEIADKKVFVSKTLSGLEISDAISDSEDFVIIEVNNE
>Mature_291_residues
GDNMKTIIVSGFLGSGKTTFINHILGFNKNTLVLENEFGDVSIDSMLIKNDDIIEINSGCICCGLKSDFKEIIHKIDKDQ
FEYIIIEPTGIAKLTDILEVLKDEENLQIQKCVTIVDSDSYICFHEDFGEFFNDQIKNADIIYITNIENLEEEKIEEVKK
SIEQFNKTAIIHTEDFRNMNPDDIVAEFENKKEHKCCCHGHGHKCCGKHHHDHHDHPHEDSKFKTNVQKNLKFASKEDLE
KFLDSKSIVRAKGNVEIADKKVFVSKTLSGLEISDAISDSEDFVIIEVNNE

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=296, Percent_Identity=25.3378378378378, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126722884, Length=296, Percent_Identity=25, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI223941779, Length=187, Percent_Identity=28.3422459893048, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI148727351, Length=297, Percent_Identity=25.5892255892256, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI146231952, Length=297, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788499, Length=243, Percent_Identity=25.9259259259259, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082430, Length=184, Percent_Identity=28.804347826087, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 33311; Mature: 33180

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDNMKTIIVSGFLGSGKTTFINHILGFNKNTLVLENEFGDVSIDSMLIKNDDIIEINSG
CCCCEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCEEECEEEECCCCEEEECCC
CICCGLKSDFKEIIHKIDKDQFEYIIIEPTGIAKLTDILEVLKDEENLQIQKCVTIVDSD
EEEECCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECC
SYICFHEDFGEFFNDQIKNADIIYITNIENLEEEKIEEVKKSIEQFNKTAIIHTEDFRNM
CEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEHHCCCC
NPDDIVAEFENKKEHKCCCHGHGHKCCGKHHHDHHDHPHEDSKFKTNVQKNLKFASKEDL
CHHHHHHHHCCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
EKFLDSKSIVRAKGNVEIADKKVFVSKTLSGLEISDAISDSEDFVIIEVNNE
HHHHCCCCEEEECCCEEEECCEEEEECCCCCCEEHHHCCCCCCEEEEEECCC
>Mature Secondary Structure 
GDNMKTIIVSGFLGSGKTTFINHILGFNKNTLVLENEFGDVSIDSMLIKNDDIIEINSG
CCCEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCEEECEEEECCCCEEEECCC
CICCGLKSDFKEIIHKIDKDQFEYIIIEPTGIAKLTDILEVLKDEENLQIQKCVTIVDSD
EEEECCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEEECC
SYICFHEDFGEFFNDQIKNADIIYITNIENLEEEKIEEVKKSIEQFNKTAIIHTEDFRNM
CEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEEHHCCCC
NPDDIVAEFENKKEHKCCCHGHGHKCCGKHHHDHHDHPHEDSKFKTNVQKNLKFASKEDL
CHHHHHHHHCCCCCCCEEECCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHH
EKFLDSKSIVRAKGNVEIADKKVFVSKTLSGLEISDAISDSEDFVIIEVNNE
HHHHCCCCEEEECCCEEEECCEEEEECCCCCCEEHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]