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The map label for this gene is adcA [H]

Identifier: 169823720

GI number: 169823720

Start: 18350

End: 19294

Strand: Direct

Name: adcA [H]

Synonym: FMG_0023

Alternate gene names: 169823720

Gene position: 18350-19294 (Clockwise)

Preceding gene: 169823719

Following gene: 169823721

Centisome position: 1.02

GC content: 34.5

Gene sequence:

>945_bases
ATGATAAAAAAATTTAGAAAATTATTGGTGCTTTTGGCGCTAGTTTTGGTTTTTGTGACTGCTTGTAGCAAACAAGATTC
AAAAACTCAAGACACAAAACAAGAAGATACGAACAAAACCAATGGAAAGAAGACAATTTATGCGACATTTTTTCCTGTAG
CAGATTTGACGAAGATGATTGTACAAGACAAGATGGATGTCAAGACTATTATCAAGACGAACGAAGAGCCGCATTCATTC
GAGCTTACGACAGATAATATGAAGGATATTTTAAAGGGAGATTTGGTTGTCTACAATGGCGCTGGAATGGAGTCTTTTGT
TGATGATTTGAAAAAATCTATGAATGATGATGGAAAGTTTTTGGATTTATCTAAGGGGCTAACTTTGTTGGATTCTTCAA
GTGAGGGTTCTGATATGAAAGCTATCAATCCACACACTTGGCTTTCAGTAAAGAATGCTGAAAAAATGTTGAATACTATT
TATGAGAAGGTGTCTGCGATTGATCCAGAAAACGAAAATTTCTATAAGAAAAATTTAGAAGATTCCACAGCCAAATTTGA
TTTGTTGGATAAAAAATTCGAGCAAGAACTTTCTAAGGTAAAGAGCAAGGAGAAGTATTTCGTGGTTTCTCATGCTGCAT
TTAATTATTTGGCAGATGATTATGGTTTGAAACAAGTTGCTGTGACTGGTATTTCTCCAGAGGATGAACCTACTGCAAAA
CAACTCAAAACTATTGCTGATTTTGTGAAGGATAAGCATATTTCTACAATATTTTTTGAAGGAAAGGCTACACCAAAAGT
TGCAGAGACTTTGGCAAAAAACACCAACACGAAAACATCTACTTTGCACACTATGGAAAATCTAGATGAAAATCAAGTTG
CCAAGGGATATTTGAAGCTTATGGAAGAAAATCTAAAATCACTTGTGGAAGCTTTTAATGAGTAG

Upstream 100 bases:

>100_bases
TTGTTTGGAAATTAAAAAATTTTAAAAAATACTTGTGAATCATTATCAATTGGTGTATTATATTAGTTGTTGCAAATAAT
TTGCATTTAAGGAGGAGTTT

Downstream 100 bases:

>100_bases
TGATGTAATTTCTGTCAGTGATTTATCTTTTGCATACGACAAAAATCTGATTTTAGATAATGTGAATTTTTCCGTAAAAG
AAGGAGATTTTGTCGCAATA

Product: putative zinc ABC transporter substrate-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MIKKFRKLLVLLALVLVFVTACSKQDSKTQDTKQEDTNKTNGKKTIYATFFPVADLTKMIVQDKMDVKTIIKTNEEPHSF
ELTTDNMKDILKGDLVVYNGAGMESFVDDLKKSMNDDGKFLDLSKGLTLLDSSSEGSDMKAINPHTWLSVKNAEKMLNTI
YEKVSAIDPENENFYKKNLEDSTAKFDLLDKKFEQELSKVKSKEKYFVVSHAAFNYLADDYGLKQVAVTGISPEDEPTAK
QLKTIADFVKDKHISTIFFEGKATPKVAETLAKNTNTKTSTLHTMENLDENQVAKGYLKLMEENLKSLVEAFNE

Sequences:

>Translated_314_residues
MIKKFRKLLVLLALVLVFVTACSKQDSKTQDTKQEDTNKTNGKKTIYATFFPVADLTKMIVQDKMDVKTIIKTNEEPHSF
ELTTDNMKDILKGDLVVYNGAGMESFVDDLKKSMNDDGKFLDLSKGLTLLDSSSEGSDMKAINPHTWLSVKNAEKMLNTI
YEKVSAIDPENENFYKKNLEDSTAKFDLLDKKFEQELSKVKSKEKYFVVSHAAFNYLADDYGLKQVAVTGISPEDEPTAK
QLKTIADFVKDKHISTIFFEGKATPKVAETLAKNTNTKTSTLHTMENLDENQVAKGYLKLMEENLKSLVEAFNE
>Mature_314_residues
MIKKFRKLLVLLALVLVFVTACSKQDSKTQDTKQEDTNKTNGKKTIYATFFPVADLTKMIVQDKMDVKTIIKTNEEPHSF
ELTTDNMKDILKGDLVVYNGAGMESFVDDLKKSMNDDGKFLDLSKGLTLLDSSSEGSDMKAINPHTWLSVKNAEKMLNTI
YEKVSAIDPENENFYKKNLEDSTAKFDLLDKKFEQELSKVKSKEKYFVVSHAAFNYLADDYGLKQVAVTGISPEDEPTAK
QLKTIADFVKDKHISTIFFEGKATPKVAETLAKNTNTKTSTLHTMENLDENQVAKGYLKLMEENLKSLVEAFNE

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=254, Percent_Identity=24.4094488188976, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35420; Mature: 35420

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKFRKLLVLLALVLVFVTACSKQDSKTQDTKQEDTNKTNGKKTIYATFFPVADLTKMI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHH
VQDKMDVKTIIKTNEEPHSFELTTDNMKDILKGDLVVYNGAGMESFVDDLKKSMNDDGKF
HHCCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCE
LDLSKGLTLLDSSSEGSDMKAINPHTWLSVKNAEKMLNTIYEKVSAIDPENENFYKKNLE
EECCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
DSTAKFDLLDKKFEQELSKVKSKEKYFVVSHAAFNYLADDYGLKQVAVTGISPEDEPTAK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHEEEECCCCCCCHHHH
QLKTIADFVKDKHISTIFFEGKATPKVAETLAKNTNTKTSTLHTMENLDENQVAKGYLKL
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHH
MEENLKSLVEAFNE
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIKKFRKLLVLLALVLVFVTACSKQDSKTQDTKQEDTNKTNGKKTIYATFFPVADLTKMI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEECCHHHHHHHH
VQDKMDVKTIIKTNEEPHSFELTTDNMKDILKGDLVVYNGAGMESFVDDLKKSMNDDGKF
HHCCHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCCE
LDLSKGLTLLDSSSEGSDMKAINPHTWLSVKNAEKMLNTIYEKVSAIDPENENFYKKNLE
EECCCCCEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHCCC
DSTAKFDLLDKKFEQELSKVKSKEKYFVVSHAAFNYLADDYGLKQVAVTGISPEDEPTAK
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHEEEECCCCCCCHHHH
QLKTIADFVKDKHISTIFFEGKATPKVAETLAKNTNTKTSTLHTMENLDENQVAKGYLKL
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHH
MEENLKSLVEAFNE
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]