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The map label for this gene is fdhA [H]

Identifier: 169630949

GI number: 169630949

Start: 3919576

End: 3921702

Strand: Reverse

Name: fdhA [H]

Synonym: MAB_3870c

Alternate gene names: 169630949

Gene position: 3921702-3919576 (Counterclockwise)

Preceding gene: 169630950

Following gene: 169630948

Centisome position: 77.39

GC content: 65.87

Gene sequence:

>2127_bases
ATGGTCGCAACCGTCGAGGGCGGCAAGCTGCTCTCACTGCGTCCCGATAAGGACAACCCGGCATCGTCGGGGTTCTCGTG
TCAGAAGGGCATCGCCTTTGCCGATGTGCACAACGATCCCGACCGGCTGACCACTCCCATGCGCCGTACGGTGTCCGGCG
AGTTCGAGCCGGTCGAGTGGGATACGGCGATGGCCGATATCGCCGAGCGCGTGCGCGCCATCCACCGGATGCATGGCTCC
GGGGCCATCGGCTGGTACTTCGGCAACCCGGGCGCGTTCAGCTACTCGCACGTGCTCTGGCTGCTGCTGCTGAGCATGGG
ATTTGGCTCCCGGCTGCACCTATTCACCGCGGGTTCGCAGGACATCAACAGCCGTTTTGTCGCCAGCCAGCTCCTCTACG
GGAACTCCGCGACAATGCCCGTCCCGGACATTCCCCGCACCGACTTGTTGGTGGTCATCGGGGCCAACCCCGTCGTGTCC
CATGGCTCGGGCGTCACCATGCCGCGAATACGGGAGCACATGAAGGCGGTGGTCAAGCGCGGCGGACGGGTGTTGGTGAT
CGATCCGCGCAAGACGGAGACCGCGGCGGATTTCGAATGGCTCGGCATTGCCCCGGACGGCGATGCCTTCCTGCTGTTGT
CGCTGCTACAGGTGATGTTTACGGAGAATCTGGTGGACAGGGCGCTGGTTGCCCAGCACGCTCGCGGTGTCGCCTGGCTC
GAGGGGCTGGTGAGGCCGTTCACCCCGGAGTCGACCCAGGCCCAGACGGGTGTGGATCCCGGCGTGGTGCGCCAGCTGGC
CCGTGATCTGGCCGGCGCCGATCGCGCGGTGGTGTATGGGCGGGTAGGCACTTGCCTTGGCCAAAATGGAACGTTGACAA
CGTATTTGCTCGATGTTGTCAATCTCGTCGCGGGTCATCTGGGCCGGGTGGGTGGCTCGATGTTCGGATCGTTCGGCATA
CCCGGCGAGCGGTTCGCCATGAAGGCGGTAGGTGCGCTGCTGGGCGCGGTGTACCGGCGGCGGCGCTCTCGCGTCGGGGG
GTTCCCTTCGGTCCTCGGCTCGGAACCTGCAGGCATCATGGCCAAAGAAATCACCACGCCGGGCCGGGGCCAGATCCGGG
CGCTGTTCGTCGGCGCGGGCAACCCCGTGCTGTCGGTGCCCAATGGTGACGAGCTGGAGGCCGCGTGCGAGCAGCTGGAC
CTCATGGTGGGGATAGACCTCTATCTCAACGAGACGTTGGCGCACTGCCACTATGTGTTGCCCGCGACCACCATGTACGA
GCGGGACGATTTCATGATTCCCTTCGCCACACTGCGGCCCGCACCGTACCGGCAGGCCACCGAGGCGGTGGTGGCTCCGG
CGGGCCAAGCCCGGCAGGAGTGGCAGATTATCGAGGACCTGACCAGCAGGCTGTGGAATCTCACCCCAGGCCTGCGGTTT
ATCGAGGGCTTGCGCAGAACGGTAGCGCTGTTCGGCGCGCGACTTCAGCCGCGTCTGCTCGCCGATGCCCTGATCAGGAT
GTCTGCCGGCGGCGACCTGTTCCGGCTGCGCCGTCAAGGACTGACCTTCGACCGGCTTACCCGTGACTATCCGCACGGCA
AGGTGCTCGCCGAGCATCTGCCGGAGGTGCCCTTGTCGCGATCGGTTTCTTACCTCGATGGCCGGATGCGTTTGGAGCAC
AAGGATATTGAGTCCGAGGTGGCCTCGCTGGCGGCGCGTGAACACGATCCTCGCTTTCCGATGCGCCTGATCGGCATGCG
AGAGGCCCGCTCGGAGAATTCGTGGATGCACAACGTGCCGATGCTCATGCGGGGCGGGCGCGTGCAGCGCGCGCTCATCC
ATGCCTATGACGCTGACCAACTTGGGGTCACCACCGACGATCTCCTGGCCATCACCTCGCCGCACGGTGAGATCGAGCTG
CCCGCTCAGGTCAGCAAGGACATCCTGCCGGGGGTTGTGGCCGTGCCACACGGCTGGGGGCACCGTCGGCGGGCGGGCTG
GAGTACCGCGAACGCCAACCCGGGCGCCAACGTGAATTTGTTGATGTCCAGCCGGCCGGAGGACCTGGAGGCACTCGCCG
GGATGGCGCATCTCAACGGAGTGCCGGTCAGGGTGCAGCGCGCGTGA

Upstream 100 bases:

>100_bases
CAAATAGGGGTCAGCCCTGTTGATGCGCATGGAAGCGGTGCCGACTATGACAGTCGAGACGAAAACGACGTTCTGCCGTA
TCTGCGAGCCGTTGTGCGGC

Downstream 100 bases:

>100_bases
CGGGGCGGGGAATGGCACTGGGCGTTGCGGGAAAGAAACGCCGAAAATACTGGCGCTATCTCTTGACGGAGGGCGTGTGA
GGCGTCAATCTGTTTGGCAG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MVATVEGGKLLSLRPDKDNPASSGFSCQKGIAFADVHNDPDRLTTPMRRTVSGEFEPVEWDTAMADIAERVRAIHRMHGS
GAIGWYFGNPGAFSYSHVLWLLLLSMGFGSRLHLFTAGSQDINSRFVASQLLYGNSATMPVPDIPRTDLLVVIGANPVVS
HGSGVTMPRIREHMKAVVKRGGRVLVIDPRKTETAADFEWLGIAPDGDAFLLLSLLQVMFTENLVDRALVAQHARGVAWL
EGLVRPFTPESTQAQTGVDPGVVRQLARDLAGADRAVVYGRVGTCLGQNGTLTTYLLDVVNLVAGHLGRVGGSMFGSFGI
PGERFAMKAVGALLGAVYRRRRSRVGGFPSVLGSEPAGIMAKEITTPGRGQIRALFVGAGNPVLSVPNGDELEAACEQLD
LMVGIDLYLNETLAHCHYVLPATTMYERDDFMIPFATLRPAPYRQATEAVVAPAGQARQEWQIIEDLTSRLWNLTPGLRF
IEGLRRTVALFGARLQPRLLADALIRMSAGGDLFRLRRQGLTFDRLTRDYPHGKVLAEHLPEVPLSRSVSYLDGRMRLEH
KDIESEVASLAAREHDPRFPMRLIGMREARSENSWMHNVPMLMRGGRVQRALIHAYDADQLGVTTDDLLAITSPHGEIEL
PAQVSKDILPGVVAVPHGWGHRRRAGWSTANANPGANVNLLMSSRPEDLEALAGMAHLNGVPVRVQRA

Sequences:

>Translated_708_residues
MVATVEGGKLLSLRPDKDNPASSGFSCQKGIAFADVHNDPDRLTTPMRRTVSGEFEPVEWDTAMADIAERVRAIHRMHGS
GAIGWYFGNPGAFSYSHVLWLLLLSMGFGSRLHLFTAGSQDINSRFVASQLLYGNSATMPVPDIPRTDLLVVIGANPVVS
HGSGVTMPRIREHMKAVVKRGGRVLVIDPRKTETAADFEWLGIAPDGDAFLLLSLLQVMFTENLVDRALVAQHARGVAWL
EGLVRPFTPESTQAQTGVDPGVVRQLARDLAGADRAVVYGRVGTCLGQNGTLTTYLLDVVNLVAGHLGRVGGSMFGSFGI
PGERFAMKAVGALLGAVYRRRRSRVGGFPSVLGSEPAGIMAKEITTPGRGQIRALFVGAGNPVLSVPNGDELEAACEQLD
LMVGIDLYLNETLAHCHYVLPATTMYERDDFMIPFATLRPAPYRQATEAVVAPAGQARQEWQIIEDLTSRLWNLTPGLRF
IEGLRRTVALFGARLQPRLLADALIRMSAGGDLFRLRRQGLTFDRLTRDYPHGKVLAEHLPEVPLSRSVSYLDGRMRLEH
KDIESEVASLAAREHDPRFPMRLIGMREARSENSWMHNVPMLMRGGRVQRALIHAYDADQLGVTTDDLLAITSPHGEIEL
PAQVSKDILPGVVAVPHGWGHRRRAGWSTANANPGANVNLLMSSRPEDLEALAGMAHLNGVPVRVQRA
>Mature_708_residues
MVATVEGGKLLSLRPDKDNPASSGFSCQKGIAFADVHNDPDRLTTPMRRTVSGEFEPVEWDTAMADIAERVRAIHRMHGS
GAIGWYFGNPGAFSYSHVLWLLLLSMGFGSRLHLFTAGSQDINSRFVASQLLYGNSATMPVPDIPRTDLLVVIGANPVVS
HGSGVTMPRIREHMKAVVKRGGRVLVIDPRKTETAADFEWLGIAPDGDAFLLLSLLQVMFTENLVDRALVAQHARGVAWL
EGLVRPFTPESTQAQTGVDPGVVRQLARDLAGADRAVVYGRVGTCLGQNGTLTTYLLDVVNLVAGHLGRVGGSMFGSFGI
PGERFAMKAVGALLGAVYRRRRSRVGGFPSVLGSEPAGIMAKEITTPGRGQIRALFVGAGNPVLSVPNGDELEAACEQLD
LMVGIDLYLNETLAHCHYVLPATTMYERDDFMIPFATLRPAPYRQATEAVVAPAGQARQEWQIIEDLTSRLWNLTPGLRF
IEGLRRTVALFGARLQPRLLADALIRMSAGGDLFRLRRQGLTFDRLTRDYPHGKVLAEHLPEVPLSRSVSYLDGRMRLEH
KDIESEVASLAAREHDPRFPMRLIGMREARSENSWMHNVPMLMRGGRVQRALIHAYDADQLGVTTDDLLAITSPHGEIEL
PAQVSKDILPGVVAVPHGWGHRRRAGWSTANANPGANVNLLMSSRPEDLEALAGMAHLNGVPVRVQRA

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=759, Percent_Identity=24.7694334650856, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI3868721, Length=485, Percent_Identity=27.0103092783505, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI87081797, Length=748, Percent_Identity=23.3957219251337, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI171474008, Length=453, Percent_Identity=25.60706401766, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1787778, Length=433, Percent_Identity=23.3256351039261, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 77228; Mature: 77228

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATVEGGKLLSLRPDKDNPASSGFSCQKGIAFADVHNDPDRLTTPMRRTVSGEFEPVEW
CEEEECCCEEEEECCCCCCCCCCCCCHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCH
DTAMADIAERVRAIHRMHGSGAIGWYFGNPGAFSYSHVLWLLLLSMGFGSRLHLFTAGSQ
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
DINSRFVASQLLYGNSATMPVPDIPRTDLLVVIGANPVVSHGSGVTMPRIREHMKAVVKR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHHC
GGRVLVIDPRKTETAADFEWLGIAPDGDAFLLLSLLQVMFTENLVDRALVAQHARGVAWL
CCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
EGLVRPFTPESTQAQTGVDPGVVRQLARDLAGADRAVVYGRVGTCLGQNGTLTTYLLDVV
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHCCCCCCHHHHHHHHH
NLVAGHLGRVGGSMFGSFGIPGERFAMKAVGALLGAVYRRRRSRVGGFPSVLGSEPAGIM
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
AKEITTPGRGQIRALFVGAGNPVLSVPNGDELEAACEQLDLMVGIDLYLNETLAHCHYVL
HHHCCCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
PATTMYERDDFMIPFATLRPAPYRQATEAVVAPAGQARQEWQIIEDLTSRLWNLTPGLRF
CCCEEECCCCCEEEHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
IEGLRRTVALFGARLQPRLLADALIRMSAGGDLFRLRRQGLTFDRLTRDYPHGKVLAEHL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHCCCCCCHHHHHHC
PEVPLSRSVSYLDGRMRLEHKDIESEVASLAAREHDPRFPMRLIGMREARSENSWMHNVP
CCCCHHCCHHHHCCHHEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHCCH
MLMRGGRVQRALIHAYDADQLGVTTDDLLAITSPHGEIELPAQVSKDILPGVVAVPHGWG
HHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECHHHHHHHCCCEEECCCCCC
HRRRAGWSTANANPGANVNLLMSSRPEDLEALAGMAHLNGVPVRVQRA
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MVATVEGGKLLSLRPDKDNPASSGFSCQKGIAFADVHNDPDRLTTPMRRTVSGEFEPVEW
CEEEECCCEEEEECCCCCCCCCCCCCHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCH
DTAMADIAERVRAIHRMHGSGAIGWYFGNPGAFSYSHVLWLLLLSMGFGSRLHLFTAGSQ
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCC
DINSRFVASQLLYGNSATMPVPDIPRTDLLVVIGANPVVSHGSGVTMPRIREHMKAVVKR
CHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHHC
GGRVLVIDPRKTETAADFEWLGIAPDGDAFLLLSLLQVMFTENLVDRALVAQHARGVAWL
CCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
EGLVRPFTPESTQAQTGVDPGVVRQLARDLAGADRAVVYGRVGTCLGQNGTLTTYLLDVV
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHCCCCCCHHHHHHHHH
NLVAGHLGRVGGSMFGSFGIPGERFAMKAVGALLGAVYRRRRSRVGGFPSVLGSEPAGIM
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCC
AKEITTPGRGQIRALFVGAGNPVLSVPNGDELEAACEQLDLMVGIDLYLNETLAHCHYVL
HHHCCCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
PATTMYERDDFMIPFATLRPAPYRQATEAVVAPAGQARQEWQIIEDLTSRLWNLTPGLRF
CCCEEECCCCCEEEHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHH
IEGLRRTVALFGARLQPRLLADALIRMSAGGDLFRLRRQGLTFDRLTRDYPHGKVLAEHL
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHCCCCCCHHHHHHC
PEVPLSRSVSYLDGRMRLEHKDIESEVASLAAREHDPRFPMRLIGMREARSENSWMHNVP
CCCCHHCCHHHHCCHHEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHCCH
MLMRGGRVQRALIHAYDADQLGVTTDDLLAITSPHGEIELPAQVSKDILPGVVAVPHGWG
HHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEECHHHHHHHCCCEEECCCCCC
HRRRAGWSTANANPGANVNLLMSSRPEDLEALAGMAHLNGVPVRVQRA
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]