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The map label for this gene is ytnA [H]

Identifier: 169630945

GI number: 169630945

Start: 3909691

End: 3911094

Strand: Reverse

Name: ytnA [H]

Synonym: MAB_3866c

Alternate gene names: 169630945

Gene position: 3911094-3909691 (Counterclockwise)

Preceding gene: 169630947

Following gene: 169630943

Centisome position: 77.18

GC content: 60.47

Gene sequence:

>1404_bases
ATGACCGTTGCCAATTCCGAATCCGAGACGCCCGACGCCGGATACTCGCGGGGCCTGTCTGCCCGCACGGTGCAGATGAT
CGCCATCGGCGGTGCCATCGGTACCGGCCTCTTCTACGGCGCCGGCGGCGCGATCGAGAAGGCCGGACCGGGGCTCATCC
TGACCTATCTGGTCGCCGGCCTGGCGATATTCGTGATCATGCGTGCACTGGGTGAATTGCTGGTCTACCGGCCGGTCTCG
GGCAGCATCTCCGAATACGCCGAGGAATTCATGGGACGTTTCGCCGGATTCGCCAACGGCTGGACCTACTGGGCGGTATG
GGCCACCACATGTATGGCCGAAATAACCGTCGCAGGTGTGTATATCCAACGGTGGTGGCCGGGCATTCCACAGTGGGTGA
CCGCGCTGGTCGTCCTGCTGATCCTGTTCGGGGCCAACCTGATATCGGTGAAAATCTTCGGTGAGGCCGAATTCTGGTTC
TCGATGATCAAGGTGACGGCGATCCTGGGCATGATCATCATCGGCGTCGGTGTACTACTGCCCATTTCGGGCTTGGGGCC
GGAGACGGGTCCCTCCGTCGCGAACCTATGGAATGACGGTGGCGTGTTTCCGACAGGCTTCAGCCAGGCACTGTTGAGTC
TGCAGATCGTGGTGTTCGCATATGTCGGTGTCGAGCTCGTCGGCGTAACGGCAGGGGAGGCGGAGAACCCGAAAGTTACG
CTGCGCAAGGCGATCAATACACTGCCCTTCCGCATCGGGTTGTTCTACGTGGGCGCGCTGATCGTCATTCTGTCGATCCA
GGGCTGGCGGAACTATCACAAGGGCGAGAGCCCCTTTGTTGCCGTATTCGAATACCTCAACATTCCGCAGGCTGCGAACA
TCGTGAACTTCATCTTGCTGACGGCCGCGCTATCTTCCTGTAATTCCGGTATCTACTCGACCGGCCGCATGGTCCGCAGC
CTCGCCCAGCGCGGTGATGCCCCCGCGGGCCTGCAGGCATTGAGTTCGCGCCACGTCCCGATGCTTGCCATCTGCTTCTC
GGCGCTGGCGATGGGTATCGGGGTATTCGTCAACTGGCTCTCGCCGGACAAGGCATTCGCCTACATCACGTCGGTGTCGA
CTATCGGCATCATCTTTGTGTGGGGTTCAATCCTGGTTTCTCACATGATCTATCGGAAGCGTGTTGCCGACGGACTACTG
CCCGCGTCGGACTACAAACTGCCCGGTGCGCCGGTGACCAATATCCTGGCGCTTGGCTTTCTGGCGCTGGTGGTATTGCT
CTTGTTCTTCACCGAGGACGGCCGAACCGCCATCTTGGTGGGCGTGGTGTGGTTCATCATCGTGGTGCTCGGCTACTTCG
TGCACCACGGTGAGCCAGCGCATCGGGAAACACAGGACGCCTAG

Upstream 100 bases:

>100_bases
CACGTGCGTATCCGACCGTTCGGGTGCTGACCGACCGATATGAGCCTCGCTGTCCGGGGTTTCCTGTGCAATAACTGTCC
GCTCACGCGATGATGTCCGG

Downstream 100 bases:

>100_bases
GCGCGGTCAATATCGAGCCTGACTTCGACCATCACCCGATCACCGGGCCCCTTGCCCAGCTGAGCCTGAATGTCCTTGCG
TACTCCGAGCACATGTCGGC

Product: putative amino acid permease

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTVANSESETPDAGYSRGLSARTVQMIAIGGAIGTGLFYGAGGAIEKAGPGLILTYLVAGLAIFVIMRALGELLVYRPVS
GSISEYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGVYIQRWWPGIPQWVTALVVLLILFGANLISVKIFGEAEFWF
SMIKVTAILGMIIIGVGVLLPISGLGPETGPSVANLWNDGGVFPTGFSQALLSLQIVVFAYVGVELVGVTAGEAENPKVT
LRKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFVAVFEYLNIPQAANIVNFILLTAALSSCNSGIYSTGRMVRS
LAQRGDAPAGLQALSSRHVPMLAICFSALAMGIGVFVNWLSPDKAFAYITSVSTIGIIFVWGSILVSHMIYRKRVADGLL
PASDYKLPGAPVTNILALGFLALVVLLLFFTEDGRTAILVGVVWFIIVVLGYFVHHGEPAHRETQDA

Sequences:

>Translated_467_residues
MTVANSESETPDAGYSRGLSARTVQMIAIGGAIGTGLFYGAGGAIEKAGPGLILTYLVAGLAIFVIMRALGELLVYRPVS
GSISEYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGVYIQRWWPGIPQWVTALVVLLILFGANLISVKIFGEAEFWF
SMIKVTAILGMIIIGVGVLLPISGLGPETGPSVANLWNDGGVFPTGFSQALLSLQIVVFAYVGVELVGVTAGEAENPKVT
LRKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFVAVFEYLNIPQAANIVNFILLTAALSSCNSGIYSTGRMVRS
LAQRGDAPAGLQALSSRHVPMLAICFSALAMGIGVFVNWLSPDKAFAYITSVSTIGIIFVWGSILVSHMIYRKRVADGLL
PASDYKLPGAPVTNILALGFLALVVLLLFFTEDGRTAILVGVVWFIIVVLGYFVHHGEPAHRETQDA
>Mature_466_residues
TVANSESETPDAGYSRGLSARTVQMIAIGGAIGTGLFYGAGGAIEKAGPGLILTYLVAGLAIFVIMRALGELLVYRPVSG
SISEYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGVYIQRWWPGIPQWVTALVVLLILFGANLISVKIFGEAEFWFS
MIKVTAILGMIIIGVGVLLPISGLGPETGPSVANLWNDGGVFPTGFSQALLSLQIVVFAYVGVELVGVTAGEAENPKVTL
RKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFVAVFEYLNIPQAANIVNFILLTAALSSCNSGIYSTGRMVRSL
AQRGDAPAGLQALSSRHVPMLAICFSALAMGIGVFVNWLSPDKAFAYITSVSTIGIIFVWGSILVSHMIYRKRVADGLLP
ASDYKLPGAPVTNILALGFLALVVLLLFFTEDGRTAILVGVVWFIIVVLGYFVHHGEPAHRETQDA

Specific function: Permease That Is Involved In The Transport Across The Cytoplasmic Membrane Of D-Alanine, D-Serine And Glycine. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790653, Length=451, Percent_Identity=43.4589800443459, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1786302, Length=450, Percent_Identity=41.5555555555556, Blast_Score=351, Evalue=7e-98,
Organism=Escherichia coli, GI1786789, Length=454, Percent_Identity=39.647577092511, Blast_Score=342, Evalue=4e-95,
Organism=Escherichia coli, GI87081915, Length=408, Percent_Identity=44.3627450980392, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI1786602, Length=452, Percent_Identity=40.4867256637168, Blast_Score=331, Evalue=5e-92,
Organism=Escherichia coli, GI48994972, Length=453, Percent_Identity=41.280353200883, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI87081708, Length=466, Percent_Identity=33.4763948497854, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI1789017, Length=418, Percent_Identity=36.8421052631579, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI1788480, Length=483, Percent_Identity=34.5755693581781, Blast_Score=240, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6324061, Length=446, Percent_Identity=30.4932735426009, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6320772, Length=452, Percent_Identity=30.5309734513274, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324990, Length=455, Percent_Identity=30.5494505494506, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322892, Length=395, Percent_Identity=32.9113924050633, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6324924, Length=436, Percent_Identity=28.4403669724771, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6324059, Length=443, Percent_Identity=32.7313769751693, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6321629, Length=412, Percent_Identity=30.0970873786408, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324553, Length=384, Percent_Identity=30.7291666666667, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=394, Percent_Identity=27.4111675126904, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6319543, Length=405, Percent_Identity=26.4197530864197, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320717, Length=403, Percent_Identity=25.5583126550869, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6321053, Length=428, Percent_Identity=27.803738317757, Blast_Score=139, Evalue=7e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=407, Percent_Identity=25.0614250614251, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=403, Percent_Identity=26.5508684863524, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324981, Length=393, Percent_Identity=29.0076335877863, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322967, Length=395, Percent_Identity=28.1012658227848, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319608, Length=455, Percent_Identity=25.9340659340659, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320364, Length=506, Percent_Identity=25.296442687747, Blast_Score=90, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49996; Mature: 49865

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVANSESETPDAGYSRGLSARTVQMIAIGGAIGTGLFYGAGGAIEKAGPGLILTYLVAG
CCCCCCCCCCCCCHHHCCCCHHHEEEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LAIFVIMRALGELLVYRPVSGSISEYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGV
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YIQRWWPGIPQWVTALVVLLILFGANLISVKIFGEAEFWFSMIKVTAILGMIIIGVGVLL
HHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
PISGLGPETGPSVANLWNDGGVFPTGFSQALLSLQIVVFAYVGVELVGVTAGEAENPKVT
CCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHH
LRKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFVAVFEYLNIPQAANIVNFILL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
TAALSSCNSGIYSTGRMVRSLAQRGDAPAGLQALSSRHVPMLAICFSALAMGIGVFVNWL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SPDKAFAYITSVSTIGIIFVWGSILVSHMIYRKRVADGLLPASDYKLPGAPVTNILALGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LALVVLLLFFTEDGRTAILVGVVWFIIVVLGYFVHHGEPAHRETQDA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TVANSESETPDAGYSRGLSARTVQMIAIGGAIGTGLFYGAGGAIEKAGPGLILTYLVAG
CCCCCCCCCCCCHHHCCCCHHHEEEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LAIFVIMRALGELLVYRPVSGSISEYAEEFMGRFAGFANGWTYWAVWATTCMAEITVAGV
HHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
YIQRWWPGIPQWVTALVVLLILFGANLISVKIFGEAEFWFSMIKVTAILGMIIIGVGVLL
HHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
PISGLGPETGPSVANLWNDGGVFPTGFSQALLSLQIVVFAYVGVELVGVTAGEAENPKVT
CCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHH
LRKAINTLPFRIGLFYVGALIVILSIQGWRNYHKGESPFVAVFEYLNIPQAANIVNFILL
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
TAALSSCNSGIYSTGRMVRSLAQRGDAPAGLQALSSRHVPMLAICFSALAMGIGVFVNWL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
SPDKAFAYITSVSTIGIIFVWGSILVSHMIYRKRVADGLLPASDYKLPGAPVTNILALGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LALVVLLLFFTEDGRTAILVGVVWFIIVVLGYFVHHGEPAHRETQDA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]