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The map label for this gene is aidB [H]

Identifier: 169630939

GI number: 169630939

Start: 3905209

End: 3906843

Strand: Reverse

Name: aidB [H]

Synonym: MAB_3860c

Alternate gene names: 169630939

Gene position: 3906843-3905209 (Counterclockwise)

Preceding gene: 169630943

Following gene: 169630938

Centisome position: 77.1

GC content: 65.57

Gene sequence:

>1635_bases
ATGGCCGATACGCATGTCGTCACCAACCAGGTTCCCGCGCTGCGCGACTACAACGCCGCGACCAGTCCCGTGTTGATGGA
AGCACTCATTCGTGAGGGTGGTCAGTGGGGTGTCGACGAGGTGCTAGAGGTGGGTGCGCTCAATGGCACTGACCGGATGC
AGCGCGCCGGGGAGTTGGCAAACCGGAACCGCCCGGTGCTGCACACGCATGACCGATGGGGCCACCGCGTCGACGAAATC
GAGTTCGACCCGGCCTATCACGAGCTCATGCGGGAGGCTGTCGCCCATGGGCTGCATGGCGCGCCCTGGGCCGACGAGCG
TCCGGGCGCCCACGTGGTACGCGCCGCGAAGACCGGTGTGTGGACGGCCGATCCCGGCCACATGTGTCCGATTTCCATGA
CCTACGCGGTGGTTCCGGCGCTGCGTGCGAACCCCGAACTTGCCGCCGTCTATGAGCCGTTGCTGTCTAGTCGGGTATAT
GACCCGGTGTTGGCGGTGCCCACTGCCAAGGCAGGTCTGACGGCGGGCATGTCGATGACCGAGAAACAGGGCGGCTCGGA
CGTGCGTGCGGGAACCACCACCGCCACGCCGAGCGCCGACGGCAGCTACACGCTGGTCGGACACAAGTGGTTCACCTCGG
CGCCAATGTGCGACGTGTTCCTGGTGCTCGCCCAGGCGCCGGGAGGCCTGTCATGTTTCTTCCTGCCGCGAGTGTTGCCC
GACGGCAGCCGTAACCGGATGCGGTTGCAGCGCTTGAAGGACAAGCTTGGCAACCACTCGAACGCGTCCTCCGAAGTTGA
GTACGACGAGGCGACCGCGTGGCTGGTTGGTGAAGAGGGCAAGGGCGTCAAGACCATCATCGAAATGGTCAACATGACGC
GCCTGGACTGCACGCTCGGATCAGCCACCAGCATGCGTACGGGTGTCGCGCTGGCCATGCATCACGCCCAGCACCGCAAG
GCCTTCGGCGAGTACTTGATCGATCAGCCCCTCATGCGCAACGTGCTCGCCGATCTGGCGATAGAGGCCGAGGCGGCAAC
CATGGTTGCCATGCGGATGGCAGGCGCCACCGACCGTGCTACTCGCGGCGACGAGACCGAGTCACTGCTGCGGCGTATCG
GCTTGGCCGCCAGCAAGTATTGGGTATGCAAGCGCGCCACCCCGCATGCCGGCGAAGCGATGGAATGCCTCGGCGGCAAC
GGCTACGTCGAGGACTCGGGGCTGCCGCGTCTCTATCGTGAGGCTCCGCTGATGGGGATCTGGGAGGGGTCCGGCAATGT
GAGCGCGCTGGACACGCTGCGGGCCATGGCCACCAAGCCCGAATGTGTCGAGGTGCTATTCAAGGAGCTTGCCCTGGCCC
AGGGGCAGGACGAGCGTCTGGATCGCCACATCAATGGATTGCATTCGCAGCTCAGCGATCTGGAATCGGTGACGTATCGT
GCCCGCAAGGTCGCCGAGGACATCTGTCTGGCGCTGCAGGGGGCGCTACTGGTCCGTCATGGCCATCCGGCCGTCGCCCA
GGCGTTCCTGGCCACCCGTCTGGCCGGTGATTGGGGTGGGGCATTCGGGACTCTGCCCACAGGGCTGGACCTTTCCCCGA
TCCTGGAGCGCGCCACCGTCAAGTCGGGCGACTGA

Upstream 100 bases:

>100_bases
AGACGACCTTCTCCACGACTTCTTTCTACTTCATGGTCCCTGGGAGAAGGCTATGTGAACAGATCTTGTGCAGTTGTCGT
GGAAATGTAACACTGAATAC

Downstream 100 bases:

>100_bases
TGGTGGACACCTTGAAGACGATGACCTACGAGGTCACCGATCGAGTCGCGCGCATCACCTTCAACCGGCCCGAGCAGGGC
AACGCCATCATCGCCGACAC

Product: acyl-CoA dehydrogenase FadE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVDEVLEVGALNGTDRMQRAGELANRNRPVLHTHDRWGHRVDEI
EFDPAYHELMREAVAHGLHGAPWADERPGAHVVRAAKTGVWTADPGHMCPISMTYAVVPALRANPELAAVYEPLLSSRVY
DPVLAVPTAKAGLTAGMSMTEKQGGSDVRAGTTTATPSADGSYTLVGHKWFTSAPMCDVFLVLAQAPGGLSCFFLPRVLP
DGSRNRMRLQRLKDKLGNHSNASSEVEYDEATAWLVGEEGKGVKTIIEMVNMTRLDCTLGSATSMRTGVALAMHHAQHRK
AFGEYLIDQPLMRNVLADLAIEAEAATMVAMRMAGATDRATRGDETESLLRRIGLAASKYWVCKRATPHAGEAMECLGGN
GYVEDSGLPRLYREAPLMGIWEGSGNVSALDTLRAMATKPECVEVLFKELALAQGQDERLDRHINGLHSQLSDLESVTYR
ARKVAEDICLALQGALLVRHGHPAVAQAFLATRLAGDWGGAFGTLPTGLDLSPILERATVKSGD

Sequences:

>Translated_544_residues
MADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVDEVLEVGALNGTDRMQRAGELANRNRPVLHTHDRWGHRVDEI
EFDPAYHELMREAVAHGLHGAPWADERPGAHVVRAAKTGVWTADPGHMCPISMTYAVVPALRANPELAAVYEPLLSSRVY
DPVLAVPTAKAGLTAGMSMTEKQGGSDVRAGTTTATPSADGSYTLVGHKWFTSAPMCDVFLVLAQAPGGLSCFFLPRVLP
DGSRNRMRLQRLKDKLGNHSNASSEVEYDEATAWLVGEEGKGVKTIIEMVNMTRLDCTLGSATSMRTGVALAMHHAQHRK
AFGEYLIDQPLMRNVLADLAIEAEAATMVAMRMAGATDRATRGDETESLLRRIGLAASKYWVCKRATPHAGEAMECLGGN
GYVEDSGLPRLYREAPLMGIWEGSGNVSALDTLRAMATKPECVEVLFKELALAQGQDERLDRHINGLHSQLSDLESVTYR
ARKVAEDICLALQGALLVRHGHPAVAQAFLATRLAGDWGGAFGTLPTGLDLSPILERATVKSGD
>Mature_543_residues
ADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVDEVLEVGALNGTDRMQRAGELANRNRPVLHTHDRWGHRVDEIE
FDPAYHELMREAVAHGLHGAPWADERPGAHVVRAAKTGVWTADPGHMCPISMTYAVVPALRANPELAAVYEPLLSSRVYD
PVLAVPTAKAGLTAGMSMTEKQGGSDVRAGTTTATPSADGSYTLVGHKWFTSAPMCDVFLVLAQAPGGLSCFFLPRVLPD
GSRNRMRLQRLKDKLGNHSNASSEVEYDEATAWLVGEEGKGVKTIIEMVNMTRLDCTLGSATSMRTGVALAMHHAQHRKA
FGEYLIDQPLMRNVLADLAIEAEAATMVAMRMAGATDRATRGDETESLLRRIGLAASKYWVCKRATPHAGEAMECLGGNG
YVEDSGLPRLYREAPLMGIWEGSGNVSALDTLRAMATKPECVEVLFKELALAQGQDERLDRHINGLHSQLSDLESVTYRA
RKVAEDICLALQGALLVRHGHPAVAQAFLATRLAGDWGGAFGTLPTGLDLSPILERATVKSGD

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=263, Percent_Identity=26.9961977186312, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4557235, Length=283, Percent_Identity=27.208480565371, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI76496475, Length=300, Percent_Identity=27, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI226958412, Length=273, Percent_Identity=26.7399267399267, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI226958414, Length=273, Percent_Identity=26.7399267399267, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI7656849, Length=273, Percent_Identity=25.2747252747253, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI4557231, Length=270, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI187960098, Length=270, Percent_Identity=23.3333333333333, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082384, Length=519, Percent_Identity=45.4720616570328, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI87081958, Length=259, Percent_Identity=27.4131274131274, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=487, Percent_Identity=30.3901437371663, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI86563383, Length=487, Percent_Identity=30.3901437371663, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17538396, Length=269, Percent_Identity=28.2527881040892, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=266, Percent_Identity=26.6917293233083, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=268, Percent_Identity=26.1194029850746, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=271, Percent_Identity=25.4612546125461, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=368, Percent_Identity=22.8260869565217, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=281, Percent_Identity=24.9110320284698, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=280, Percent_Identity=26.0714285714286, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71985192, Length=227, Percent_Identity=25.5506607929515, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363737, Length=385, Percent_Identity=25.1948051948052, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356377, Length=263, Percent_Identity=26.2357414448669, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646207, Length=276, Percent_Identity=25, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355753, Length=265, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666513, Length=283, Percent_Identity=25.4416961130742, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 58754; Mature: 58622

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVDEVLEVGALNGTDRMQRAGELA
CCCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHH
NRNRPVLHTHDRWGHRVDEIEFDPAYHELMREAVAHGLHGAPWADERPGAHVVRAAKTGV
HCCCCEEECCHHHCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
WTADPGHMCPISMTYAVVPALRANPELAAVYEPLLSSRVYDPVLAVPTAKAGLTAGMSMT
EECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHHHHHCCCHH
EKQGGSDVRAGTTTATPSADGSYTLVGHKWFTSAPMCDVFLVLAQAPGGLSCFFLPRVLP
HHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEHHHHCC
DGSRNRMRLQRLKDKLGNHSNASSEVEYDEATAWLVGEEGKGVKTIIEMVNMTRLDCTLG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEECC
SATSMRTGVALAMHHAQHRKAFGEYLIDQPLMRNVLADLAIEAEAATMVAMRMAGATDRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TRGDETESLLRRIGLAASKYWVCKRATPHAGEAMECLGGNGYVEDSGLPRLYREAPLMGI
CCCCHHHHHHHHHCCHHHHEEEEECCCCCCCCHHHHHCCCCEECCCCCCHHHHHCCCEEE
WEGSGNVSALDTLRAMATKPECVEVLFKELALAQGQDERLDRHINGLHSQLSDLESVTYR
ECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARKVAEDICLALQGALLVRHGHPAVAQAFLATRLAGDWGGAFGTLPTGLDLSPILERATV
HHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
KSGD
CCCC
>Mature Secondary Structure 
ADTHVVTNQVPALRDYNAATSPVLMEALIREGGQWGVDEVLEVGALNGTDRMQRAGELA
CCCCEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHH
NRNRPVLHTHDRWGHRVDEIEFDPAYHELMREAVAHGLHGAPWADERPGAHVVRAAKTGV
HCCCCEEECCHHHCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCC
WTADPGHMCPISMTYAVVPALRANPELAAVYEPLLSSRVYDPVLAVPTAKAGLTAGMSMT
EECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCCCCHHHHHHCCCHH
EKQGGSDVRAGTTTATPSADGSYTLVGHKWFTSAPMCDVFLVLAQAPGGLSCFFLPRVLP
HHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEHHHHCC
DGSRNRMRLQRLKDKLGNHSNASSEVEYDEATAWLVGEEGKGVKTIIEMVNMTRLDCTLG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEECC
SATSMRTGVALAMHHAQHRKAFGEYLIDQPLMRNVLADLAIEAEAATMVAMRMAGATDRA
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TRGDETESLLRRIGLAASKYWVCKRATPHAGEAMECLGGNGYVEDSGLPRLYREAPLMGI
CCCCHHHHHHHHHCCHHHHEEEEECCCCCCCCHHHHHCCCCEECCCCCCHHHHHCCCEEE
WEGSGNVSALDTLRAMATKPECVEVLFKELALAQGQDERLDRHINGLHSQLSDLESVTYR
ECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ARKVAEDICLALQGALLVRHGHPAVAQAFLATRLAGDWGGAFGTLPTGLDLSPILERATV
HHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHC
KSGD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]