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The map label for this gene is yfnA [H]

Identifier: 169630921

GI number: 169630921

Start: 3887913

End: 3889388

Strand: Direct

Name: yfnA [H]

Synonym: MAB_3842

Alternate gene names: 169630921

Gene position: 3887913-3889388 (Clockwise)

Preceding gene: 169630920

Following gene: 169630922

Centisome position: 76.73

GC content: 63.89

Gene sequence:

>1476_bases
ATGGCACCTTCGTCACCCAGCCTTGCCCAGCAACTGCTGCGGCGCCGTCCGACCTCGGGTGCTCCCACCGCCCACGGCGC
CGGAGGGCACCTCAAGCAGTCGATGGGAACCTTCCAGCTGACCATGATCGGTGTCGGTGCCACGGTGGGCACCGGTATCT
TCTTCATCCTCGCCGAATCAGTGCCCAAGGCGGGTCCTGCGGTGATGGCCTCGTTCCTGGTCGCCGGCCTCGCCGCCGGA
CTAGCCGCACTCTGTTACGCCGAGCTAGCCTCCGCAGTACCGGTATCGGGTTCCTCGTTCTCCTACGCCTACACAACCTT
GGGTGAGCTGGCGGCGATGGTAGTGGCAGCCTGCCTGCTGTTGGAATATGGGGTGTCGGCCGCGGCGGTCGCCGTCGGCT
GGAGCCAGTACCTTGACAAGCTCTTGGTCAATCTCTTCGGATGGCATCTGCCGCATGCGATCAGCGCCGCGCCTTGGGAC
AGCGCCGATCCCGCGGCACCGCATCCCTGGCTCAATCTTCCCGCGGTCCTGCTCATCATCATGTGCGCAATCCTGCTCAT
TCGCGGCACCAGCGAATCCGCGCTGGTCAACACCGTCATGGTGCTGCTTAAACTCGCCGTCCTTTCCGTGTTCGCGATCA
TCGCGTTCACCGCATTCCACGCCGGCAACTTCTCCGACTTCGCACCGTTCGGGGTCAGTGGGATCGGGGCCGCGGCGGGG
ACGATCTTCTTCACCTATGTGGGGCTCGATACGGTGTCCACTGCGGGGGAGGAAGTGAAGGATCCGCAGCGGACCATGCC
GCGCGCGCTGATCGCAGCCCTGCTCATCGTCACTGCCTTCTACCTCGTCGTCGCGCTCGCCGCGCTGGGTGCGCAACCCT
GGAAAGAGTTCGAGGGGCAGTCCGCCGGCCTGGCCCTGATTTTGGACAAGGTCACCGGAAGCACCTCTGCCAGTACATTC
CTCGCGGCGGGCGCGGTGATTTCGATTTTCTCGATCACCCTGGTCTCGATGTACGGCCAGACACGCATTCTCTTCGCGAT
CGGCCGCGACGGCCTGCTCCCGTCGGTCTTCGCACAGGTCAACCCCCGCACGCTGACCCCGGTGAACAACACGATCATCG
TCGCCGTGGTGGTGGGCTTCATGGCCGCCTTCGTACCCCTGGACAGCCTGGCGAACATGGTGTCGATCGGAACACTTACC
GCCTTCATCGTCGTATCGATCGGCGTCATCATCCTGCGGGTGCGTGAACCCGAGTTGCCGCGCGCCTTCCGTGTTCCGGG
CTATCCGGTGACTCCTGTCCTGTCCGTCATCGCCTGCGGGTACATCCTGTTCAGCCTGCCCTGGATCACCTGGATTGCCT
TCGGCGCCTGGGTTGCCATCGTGCTGGTGTTCTATTTGGTGTGGGGCCGGCACCACAGCGCGCTGAACGACCTGCCCAGC
GACCCAGCAGAATTATCGGAGAAGGAACCGGTATGA

Upstream 100 bases:

>100_bases
CCCCTTGTCATCACCGAGGGCGAAATCGATTGGGCGGTAGACCAGTTCGCTGATGCGCTGGCCAGCTTCCGGTAGCTTTC
GCCCCGCCACAGGAGGCAAC

Downstream 100 bases:

>100_bases
CCGTCGTCGTCGGATACCTTTCGGGCAAGGGCGGCAAGGGCGCCCTGCACCTGGCGGTCGAATCTGCTCGTGTACTGGAA
ACCTCGCTCACTGTCACCAC

Product: cationic amino acid transport integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MAPSSPSLAQQLLRRRPTSGAPTAHGAGGHLKQSMGTFQLTMIGVGATVGTGIFFILAESVPKAGPAVMASFLVAGLAAG
LAALCYAELASAVPVSGSSFSYAYTTLGELAAMVVAACLLLEYGVSAAAVAVGWSQYLDKLLVNLFGWHLPHAISAAPWD
SADPAAPHPWLNLPAVLLIIMCAILLIRGTSESALVNTVMVLLKLAVLSVFAIIAFTAFHAGNFSDFAPFGVSGIGAAAG
TIFFTYVGLDTVSTAGEEVKDPQRTMPRALIAALLIVTAFYLVVALAALGAQPWKEFEGQSAGLALILDKVTGSTSASTF
LAAGAVISIFSITLVSMYGQTRILFAIGRDGLLPSVFAQVNPRTLTPVNNTIIVAVVVGFMAAFVPLDSLANMVSIGTLT
AFIVVSIGVIILRVREPELPRAFRVPGYPVTPVLSVIACGYILFSLPWITWIAFGAWVAIVLVFYLVWGRHHSALNDLPS
DPAELSEKEPV

Sequences:

>Translated_491_residues
MAPSSPSLAQQLLRRRPTSGAPTAHGAGGHLKQSMGTFQLTMIGVGATVGTGIFFILAESVPKAGPAVMASFLVAGLAAG
LAALCYAELASAVPVSGSSFSYAYTTLGELAAMVVAACLLLEYGVSAAAVAVGWSQYLDKLLVNLFGWHLPHAISAAPWD
SADPAAPHPWLNLPAVLLIIMCAILLIRGTSESALVNTVMVLLKLAVLSVFAIIAFTAFHAGNFSDFAPFGVSGIGAAAG
TIFFTYVGLDTVSTAGEEVKDPQRTMPRALIAALLIVTAFYLVVALAALGAQPWKEFEGQSAGLALILDKVTGSTSASTF
LAAGAVISIFSITLVSMYGQTRILFAIGRDGLLPSVFAQVNPRTLTPVNNTIIVAVVVGFMAAFVPLDSLANMVSIGTLT
AFIVVSIGVIILRVREPELPRAFRVPGYPVTPVLSVIACGYILFSLPWITWIAFGAWVAIVLVFYLVWGRHHSALNDLPS
DPAELSEKEPV
>Mature_490_residues
APSSPSLAQQLLRRRPTSGAPTAHGAGGHLKQSMGTFQLTMIGVGATVGTGIFFILAESVPKAGPAVMASFLVAGLAAGL
AALCYAELASAVPVSGSSFSYAYTTLGELAAMVVAACLLLEYGVSAAAVAVGWSQYLDKLLVNLFGWHLPHAISAAPWDS
ADPAAPHPWLNLPAVLLIIMCAILLIRGTSESALVNTVMVLLKLAVLSVFAIIAFTAFHAGNFSDFAPFGVSGIGAAAGT
IFFTYVGLDTVSTAGEEVKDPQRTMPRALIAALLIVTAFYLVVALAALGAQPWKEFEGQSAGLALILDKVTGSTSASTFL
AAGAVISIFSITLVSMYGQTRILFAIGRDGLLPSVFAQVNPRTLTPVNNTIIVAVVVGFMAAFVPLDSLANMVSIGTLTA
FIVVSIGVIILRVREPELPRAFRVPGYPVTPVLSVIACGYILFSLPWITWIAFGAWVAIVLVFYLVWGRHHSALNDLPSD
PAELSEKEPV

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=447, Percent_Identity=33.3333333333333, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI114326544, Length=445, Percent_Identity=31.685393258427, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI114326550, Length=445, Percent_Identity=31.685393258427, Blast_Score=192, Evalue=9e-49,
Organism=Homo sapiens, GI258614003, Length=442, Percent_Identity=32.3529411764706, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI258614005, Length=442, Percent_Identity=32.3529411764706, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI258645169, Length=442, Percent_Identity=33.2579185520362, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI110347453, Length=415, Percent_Identity=32.289156626506, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI181337167, Length=400, Percent_Identity=33, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI33286428, Length=481, Percent_Identity=24.948024948025, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI71979932, Length=476, Percent_Identity=25.4201680672269, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI187423910, Length=431, Percent_Identity=23.6658932714617, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI7657591, Length=431, Percent_Identity=23.6658932714617, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI186910308, Length=413, Percent_Identity=23.9709443099274, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI186910306, Length=413, Percent_Identity=23.9709443099274, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI186910304, Length=413, Percent_Identity=23.9709443099274, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI115648063, Length=442, Percent_Identity=21.9457013574661, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI115648022, Length=442, Percent_Identity=21.9457013574661, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7657683, Length=414, Percent_Identity=22.9468599033816, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI33286430, Length=242, Percent_Identity=24.7933884297521, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081869, Length=411, Percent_Identity=24.330900243309, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786789, Length=460, Percent_Identity=22.6086956521739, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786302, Length=397, Percent_Identity=24.1813602015113, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789017, Length=468, Percent_Identity=24.3589743589744, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786602, Length=480, Percent_Identity=21.4583333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081915, Length=445, Percent_Identity=23.8202247191011, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082250, Length=468, Percent_Identity=25.2136752136752, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788480, Length=445, Percent_Identity=23.1460674157303, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082023, Length=410, Percent_Identity=24.8780487804878, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786694, Length=396, Percent_Identity=24.7474747474747, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790653, Length=417, Percent_Identity=21.1031175059952, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI2367353, Length=363, Percent_Identity=25.6198347107438, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=398, Percent_Identity=35.427135678392, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17533459, Length=417, Percent_Identity=31.1750599520384, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17531343, Length=419, Percent_Identity=29.8329355608592, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI71993915, Length=415, Percent_Identity=21.6867469879518, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI32566699, Length=377, Percent_Identity=26.2599469496021, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=439, Percent_Identity=21.8678815489749, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193208714, Length=427, Percent_Identity=23.8875878220141, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566695, Length=427, Percent_Identity=23.8875878220141, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995388, Length=416, Percent_Identity=24.5192307692308, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=416, Percent_Identity=24.5192307692308, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17537453, Length=418, Percent_Identity=23.2057416267943, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221512776, Length=430, Percent_Identity=32.7906976744186, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24666159, Length=430, Percent_Identity=32.7906976744186, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24668806, Length=470, Percent_Identity=29.7872340425532, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI21356285, Length=470, Percent_Identity=29.7872340425532, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24668802, Length=470, Percent_Identity=29.7872340425532, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24667468, Length=409, Percent_Identity=33.9853300733496, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI281366235, Length=426, Percent_Identity=30.2816901408451, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI116007820, Length=426, Percent_Identity=30.2816901408451, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI116007818, Length=423, Percent_Identity=30.4964539007092, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI85725152, Length=423, Percent_Identity=30.4964539007092, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI161077963, Length=439, Percent_Identity=28.7015945330296, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI221331183, Length=436, Percent_Identity=26.3761467889908, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17647653, Length=436, Percent_Identity=26.3761467889908, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24664379, Length=436, Percent_Identity=26.3761467889908, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357367, Length=441, Percent_Identity=22.9024943310658, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24641993, Length=433, Percent_Identity=23.3256351039261, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641995, Length=433, Percent_Identity=23.3256351039261, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24651635, Length=420, Percent_Identity=24.7619047619048, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24651633, Length=420, Percent_Identity=24.7619047619048, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550968, Length=425, Percent_Identity=24.4705882352941, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19921172, Length=425, Percent_Identity=24.4705882352941, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51286; Mature: 51155

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSSPSLAQQLLRRRPTSGAPTAHGAGGHLKQSMGTFQLTMIGVGATVGTGIFFILAES
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHH
VPKAGPAVMASFLVAGLAAGLAALCYAELASAVPVSGSSFSYAYTTLGELAAMVVAACLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LEYGVSAAAVAVGWSQYLDKLLVNLFGWHLPHAISAAPWDSADPAAPHPWLNLPAVLLII
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
MCAILLIRGTSESALVNTVMVLLKLAVLSVFAIIAFTAFHAGNFSDFAPFGVSGIGAAAG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
TIFFTYVGLDTVSTAGEEVKDPQRTMPRALIAALLIVTAFYLVVALAALGAQPWKEFEGQ
HHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
SAGLALILDKVTGSTSASTFLAAGAVISIFSITLVSMYGQTRILFAIGRDGLLPSVFAQV
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHC
NPRTLTPVNNTIIVAVVVGFMAAFVPLDSLANMVSIGTLTAFIVVSIGVIILRVREPELP
CCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
RAFRVPGYPVTPVLSVIACGYILFSLPWITWIAFGAWVAIVLVFYLVWGRHHSALNDLPS
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
DPAELSEKEPV
CHHHCCCCCCC
>Mature Secondary Structure 
APSSPSLAQQLLRRRPTSGAPTAHGAGGHLKQSMGTFQLTMIGVGATVGTGIFFILAES
CCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCHHHHHHHHHHHHHH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CHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]