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The map label for this gene is pdxH [H]

Identifier: 169630903

GI number: 169630903

Start: 3868840

End: 3869508

Strand: Direct

Name: pdxH [H]

Synonym: MAB_3823

Alternate gene names: 169630903

Gene position: 3868840-3869508 (Clockwise)

Preceding gene: 169630902

Following gene: 169630904

Centisome position: 76.35

GC content: 66.82

Gene sequence:

>669_bases
GTGCGCTGGCTCGATGCCGACGGAGGGCGTTCTTTTCTACGGGCACTGCCCGTTCTGTCCGGCAACGCACCGCCCTTTGA
CATCGCCTCCGCCCCCGCCGAACCGCTTCGCTTGTTCATCGAATGGATCGAGCAGGCCGCGCAGGCCGGGGTGCAGGAAC
CGCACGCGATGACCATTTCGACCGTCGACAACGCGGGGATGCCGCGTGCACGGGTGCTGATCCTCAAAGCCATCGACCAG
GATGGCTGGCATTTCGCGGCGAGCTCGGTGAGTCAGAAGGGGCGCGATCTGTCCGCTAACCCCGCCGCCGCGCTGACCTT
CCATTGGCCCGAGGTAGTGCGACAGGTGCGAGTGGTGGGCGCGGTGGTGGACGACGGCGACCAGGTAAGCGCCGCCGACT
TCCTCGGCAGACCCGTCGGATCGCGGGCGATGGCGTTGACACTGCGCCAGAGCCAGCCGCTGGTGGATCCGGCGGAAATC
GACGCGGAGATCGAGAAGGCCCACCGGAAGTTGGCCGACGACCCCGAACTGGTGCCGGACGAGTGGGTCTCGTATGCCCT
GCGGCCGGCGCAGATCGAGTTTTGGCAAGGCTCCCCCGATCGCAAGCACCAGCGTCTCAGTTATCAGTGGGTTGGAGACG
GCTGGGAGCGCACGCAGCTCTGGCCGTAG

Upstream 100 bases:

>100_bases
CCCGCGGTAGCCCCCTCGGGGTGGCGAGAGGAACCCGGTGACCTGCGGTTCCGGGAGCATGTGGAACGGTAATACACGAT
CCACATGAGGAGGTTGTGCG

Downstream 100 bases:

>100_bases
CCCGGGCGAGTTCGCGGCAGTATTCGCGCTGATCTTACTTTCGAGTAAGGTACGCACCGTGAGCGCATCTCCGACCTACA
AGATCTGGCAGCGTCTGCAG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRWLDADGGRSFLRALPVLSGNAPPFDIASAPAEPLRLFIEWIEQAAQAGVQEPHAMTISTVDNAGMPRARVLILKAIDQ
DGWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVGAVVDDGDQVSAADFLGRPVGSRAMALTLRQSQPLVDPAEI
DAEIEKAHRKLADDPELVPDEWVSYALRPAQIEFWQGSPDRKHQRLSYQWVGDGWERTQLWP

Sequences:

>Translated_222_residues
MRWLDADGGRSFLRALPVLSGNAPPFDIASAPAEPLRLFIEWIEQAAQAGVQEPHAMTISTVDNAGMPRARVLILKAIDQ
DGWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVGAVVDDGDQVSAADFLGRPVGSRAMALTLRQSQPLVDPAEI
DAEIEKAHRKLADDPELVPDEWVSYALRPAQIEFWQGSPDRKHQRLSYQWVGDGWERTQLWP
>Mature_222_residues
MRWLDADGGRSFLRALPVLSGNAPPFDIASAPAEPLRLFIEWIEQAAQAGVQEPHAMTISTVDNAGMPRARVLILKAIDQ
DGWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVGAVVDDGDQVSAADFLGRPVGSRAMALTLRQSQPLVDPAEI
DAEIEKAHRKLADDPELVPDEWVSYALRPAQIEFWQGSPDRKHQRLSYQWVGDGWERTQLWP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=177, Percent_Identity=33.8983050847458, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=32.4607329842932, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17553712, Length=196, Percent_Identity=32.1428571428571, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319509, Length=195, Percent_Identity=32.3076923076923, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24644901, Length=180, Percent_Identity=32.2222222222222, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45551845, Length=180, Percent_Identity=32.2222222222222, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24574; Mature: 24574

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLDADGGRSFLRALPVLSGNAPPFDIASAPAEPLRLFIEWIEQAAQAGVQEPHAMTIS
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TVDNAGMPRARVLILKAIDQDGWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVG
ECCCCCCCHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
AVVDDGDQVSAADFLGRPVGSRAMALTLRQSQPLVDPAEIDAEIEKAHRKLADDPELVPD
HEECCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHH
EWVSYALRPAQIEFWQGSPDRKHQRLSYQWVGDGWERTQLWP
HHHHHHCCCCEEEEECCCCCCHHHEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRWLDADGGRSFLRALPVLSGNAPPFDIASAPAEPLRLFIEWIEQAAQAGVQEPHAMTIS
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
TVDNAGMPRARVLILKAIDQDGWHFAASSVSQKGRDLSANPAAALTFHWPEVVRQVRVVG
ECCCCCCCHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
AVVDDGDQVSAADFLGRPVGSRAMALTLRQSQPLVDPAEIDAEIEKAHRKLADDPELVPD
HEECCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCHH
EWVSYALRPAQIEFWQGSPDRKHQRLSYQWVGDGWERTQLWP
HHHHHHCCCCEEEEECCCCCCHHHEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA