| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is glmS [H]
Identifier: 169630822
GI number: 169630822
Start: 3796976
End: 3798841
Strand: Reverse
Name: glmS [H]
Synonym: MAB_3743c
Alternate gene names: 169630822
Gene position: 3798841-3796976 (Counterclockwise)
Preceding gene: 169630824
Following gene: 169630821
Centisome position: 74.97
GC content: 64.74
Gene sequence:
>1866_bases ATGTGCGGAATTGTCGGGTACGTCGGCCACCGGGACGCCCTCAGTGTCGTCCTTGAGGCGCTGAGGCGGCTCGAATACCG CGGCTACGACTCTGCCGGGGTGGCGCTGGCCGATGGCCACGGCGGGCTGCTGGTGCAGCGCAAGGCGGGCCGACTGGCGA ATCTGGAATCTGCGATCGCCGAGTCCGGGGAATCTTTCGCCGCCACGACCGGGATGGGACATACCCGCTGGGCCACTCAC GGCGCGCCCACCGACCGCAACGCCCACCCGCATCAGGATGCCACCGGCAAGGTCGCGGTGGTCCATAACGGGATCATCGA GAACTTCGCGGTACTGCGCGCCGAGCTGGAGTCGGCCGGTGTCGAATTCGCCAGTGACACGGACTCCGAGGTGGCCGTGC ATCTGGTGTCGCGCCAGTTCGAATCCGGCGACACCGCCGGTGACTTCGTCGCCTCGGTGCAGTCCGTCGTGCGTCGGCTG GAGGGGCATTTCACTCTCGTCTTCTCTCACGCGGACGACCCGGGCACCATCGTGGCCGCGCGCCGGTCTACGCCGCTGGT TGTCGGCATCGGTGACGGCGAGATGTTCCTCGGGTCCGACGTCGCGGCGTTCATCGAATACACCAGGGATGCTGTCGAAT TGGGGCAGGATCAGGTCGTCGTCATCACCGCGGACGGATACCGCATCACCGATTTCGAGGGCAATGACGACACCGGGAAC GCCCGGGTGTTCACCATCGATTGGGATCTGTCGGCCGCGGAAAAGGGCGGTTACGAGTACTTCATGCTCAAGGAGATCGC CGAACAGCCGGCGGCGGTTTCCGACACCTTGCTGGGTCACTTCGATCTCGACCGGATAGTGCTCGACGAGCAGCGGCTCT CCGATCAGGAGCTGCGCGATATCGACAAGGTATTCGTGGTGGCCTGTGGCACCGCGTTCCATTCCGGGCTGCTGGCCAAG TACGCCATTGAGCACTGGACGCGGCTGCCCGTGGAGATCGAACTCGCCAGTGAATTCCGGTACCGTGACCCGGTTTTGGA TCGCAGCACGCTGGTGGTGGCCATCTCCCAGTCGGGTGAGACCGCCGACACGTTGGAAGCGGTGCGACACGCCAAGGAAC AGAAGGCCAAGGTGCTGGCGGTCTGCAACACCAATGGCTCGCAGATTCCCCGCGAGTGCGATGCGGTGTTGTACACCAGG GCCGGGCCGGAGATCGGTGTCGCCGCCACGAAGACCTTCCTGGCCCAGGTGACCGCCAATTACATTGTGGGCCTTGCCCT GGCCCAGGCTCGGGGGACCAAGTACCCCGATGAGGTGGCGCGTGAGTACCACGAGCTGGAGGCCATGCCGGAGCTGATCG AGCGCGTCATCTCCCAGATGGATCCGGTCGCCGACCTTGCCCGGCAGTACGCGCAGTCCTCCAGCATCCTGTTCTTGGGA CGCCATGTCGGTTACCCGGTGGCGCTCGAAGGCGCGCTCAAGCTCAAGGAACTGGCCTATATGCACGCCGAGGGCTTCGC GGCCGGCGAGCTCAAGCACGGCCCCATCGCGCTGATCGAGGAGGGATTGCCGGTCATTGTGGTGATGCCCTCCCCCAAGG GTATGGGTCTGCTGCACTCCAAGCTGCTCAGCAATATCCGCGAGATCCAGGCCCGCGGGGCACGCACGATCGTCATCGCC GAAGAGGGCGACGAGACGATTCGGCCCTACGCGGACCACCTCATCGAGATCCCCGCGGTATCGACGCTGTACCAACCGCT GCTGTCCACGATTCCCATGCAGGTCTTCGCCGCTGCCGTGGCGCAGGCCCGTGGTTATGACGTGGATAAGCCGCGGAACT TGGCCAAGTCGGTAACCGTCGAATAA
Upstream 100 bases:
>100_bases GTCAGGGCTTTGAATAGCGTGCGGGTACTCGCCATGGCATGACCGTAGCTGATACCGGCGCCCGTGGACCTCAGCGGGAA CTGAACTACCCTGGTGGGCT
Downstream 100 bases:
>100_bases GCGGCAGCCGTAGGCCGAGTGCATGAGCCCTGTCGCGGTACCCGAGCATCGTGTCGGAAAGCATTGGGCTGTGCAGAAGT TGGGGCATTTCGTCGATGCG
Product: glucosamine--fructose-6-phosphate aminotransferase
Products: NA
Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]
Number of amino acids: Translated: 621; Mature: 621
Protein sequence:
>621_residues MCGIVGYVGHRDALSVVLEALRRLEYRGYDSAGVALADGHGGLLVQRKAGRLANLESAIAESGESFAATTGMGHTRWATH GAPTDRNAHPHQDATGKVAVVHNGIIENFAVLRAELESAGVEFASDTDSEVAVHLVSRQFESGDTAGDFVASVQSVVRRL EGHFTLVFSHADDPGTIVAARRSTPLVVGIGDGEMFLGSDVAAFIEYTRDAVELGQDQVVVITADGYRITDFEGNDDTGN ARVFTIDWDLSAAEKGGYEYFMLKEIAEQPAAVSDTLLGHFDLDRIVLDEQRLSDQELRDIDKVFVVACGTAFHSGLLAK YAIEHWTRLPVEIELASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAVCNTNGSQIPRECDAVLYTR AGPEIGVAATKTFLAQVTANYIVGLALAQARGTKYPDEVAREYHELEAMPELIERVISQMDPVADLARQYAQSSSILFLG RHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVIVVMPSPKGMGLLHSKLLSNIREIQARGARTIVIA EEGDETIRPYADHLIEIPAVSTLYQPLLSTIPMQVFAAAVAQARGYDVDKPRNLAKSVTVE
Sequences:
>Translated_621_residues MCGIVGYVGHRDALSVVLEALRRLEYRGYDSAGVALADGHGGLLVQRKAGRLANLESAIAESGESFAATTGMGHTRWATH GAPTDRNAHPHQDATGKVAVVHNGIIENFAVLRAELESAGVEFASDTDSEVAVHLVSRQFESGDTAGDFVASVQSVVRRL EGHFTLVFSHADDPGTIVAARRSTPLVVGIGDGEMFLGSDVAAFIEYTRDAVELGQDQVVVITADGYRITDFEGNDDTGN ARVFTIDWDLSAAEKGGYEYFMLKEIAEQPAAVSDTLLGHFDLDRIVLDEQRLSDQELRDIDKVFVVACGTAFHSGLLAK YAIEHWTRLPVEIELASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAVCNTNGSQIPRECDAVLYTR AGPEIGVAATKTFLAQVTANYIVGLALAQARGTKYPDEVAREYHELEAMPELIERVISQMDPVADLARQYAQSSSILFLG RHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVIVVMPSPKGMGLLHSKLLSNIREIQARGARTIVIA EEGDETIRPYADHLIEIPAVSTLYQPLLSTIPMQVFAAAVAQARGYDVDKPRNLAKSVTVE >Mature_621_residues MCGIVGYVGHRDALSVVLEALRRLEYRGYDSAGVALADGHGGLLVQRKAGRLANLESAIAESGESFAATTGMGHTRWATH GAPTDRNAHPHQDATGKVAVVHNGIIENFAVLRAELESAGVEFASDTDSEVAVHLVSRQFESGDTAGDFVASVQSVVRRL EGHFTLVFSHADDPGTIVAARRSTPLVVGIGDGEMFLGSDVAAFIEYTRDAVELGQDQVVVITADGYRITDFEGNDDTGN ARVFTIDWDLSAAEKGGYEYFMLKEIAEQPAAVSDTLLGHFDLDRIVLDEQRLSDQELRDIDKVFVVACGTAFHSGLLAK YAIEHWTRLPVEIELASEFRYRDPVLDRSTLVVAISQSGETADTLEAVRHAKEQKAKVLAVCNTNGSQIPRECDAVLYTR AGPEIGVAATKTFLAQVTANYIVGLALAQARGTKYPDEVAREYHELEAMPELIERVISQMDPVADLARQYAQSSSILFLG RHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVIVVMPSPKGMGLLHSKLLSNIREIQARGARTIVIA EEGDETIRPYADHLIEIPAVSTLYQPLLSTIPMQVFAAAVAQARGYDVDKPRNLAKSVTVE
Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]
COG id: COG0449
COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 SIS domains [H]
Homologues:
Organism=Homo sapiens, GI4826742, Length=694, Percent_Identity=36.8876080691643, Blast_Score=414, Evalue=1e-116, Organism=Homo sapiens, GI205277386, Length=693, Percent_Identity=36.2193362193362, Blast_Score=398, Evalue=1e-111, Organism=Homo sapiens, GI29570798, Length=201, Percent_Identity=28.8557213930348, Blast_Score=75, Evalue=2e-13, Organism=Escherichia coli, GI1790167, Length=623, Percent_Identity=42.6966292134831, Blast_Score=472, Evalue=1e-134, Organism=Caenorhabditis elegans, GI17532899, Length=723, Percent_Identity=33.4716459197787, Blast_Score=359, Evalue=2e-99, Organism=Caenorhabditis elegans, GI17532897, Length=736, Percent_Identity=32.8804347826087, Blast_Score=353, Evalue=1e-97, Organism=Caenorhabditis elegans, GI17539970, Length=716, Percent_Identity=32.5418994413408, Blast_Score=351, Evalue=6e-97, Organism=Saccharomyces cerevisiae, GI6322745, Length=436, Percent_Identity=35.0917431192661, Blast_Score=243, Evalue=7e-65, Organism=Saccharomyces cerevisiae, GI6323731, Length=435, Percent_Identity=28.735632183908, Blast_Score=176, Evalue=9e-45, Organism=Saccharomyces cerevisiae, GI6323730, Length=231, Percent_Identity=32.4675324675325, Blast_Score=124, Evalue=5e-29, Organism=Drosophila melanogaster, GI21357745, Length=700, Percent_Identity=35.4285714285714, Blast_Score=412, Evalue=1e-115,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000583 - InterPro: IPR017932 - InterPro: IPR005855 - InterPro: IPR001347 [H]
Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]
EC number: =2.6.1.16 [H]
Molecular weight: Translated: 67197; Mature: 67197
Theoretical pI: Translated: 4.81; Mature: 4.81
Prosite motif: PS00443 GATASE_TYPE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MCGIVGYVGHRDALSVVLEALRRLEYRGYDSAGVALADGHGGLLVQRKAGRLANLESAIA CCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHH ESGESFAATTGMGHTRWATHGAPTDRNAHPHQDATGKVAVVHNGIIENFAVLRAELESAG HCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCC VEFASDTDSEVAVHLVSRQFESGDTAGDFVASVQSVVRRLEGHFTLVFSHADDPGTIVAA CEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE RRSTPLVVGIGDGEMFLGSDVAAFIEYTRDAVELGQDQVVVITADGYRITDFEGNDDTGN ECCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCCC ARVFTIDWDLSAAEKGGYEYFMLKEIAEQPAAVSDTLLGHFDLDRIVLDEQRLSDQELRD EEEEEEECCCCHHCCCCCEEEHHHHHHHCCCHHHHHHHCCCCCHHHEECHHHCCHHHHHH IDKVFVVACGTAFHSGLLAKYAIEHWTRLPVEIELASEFRYRDPVLDRSTLVVAISQSGE HHHHHHEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCC TADTLEAVRHAKEQKAKVLAVCNTNGSQIPRECDAVLYTRAGPEIGVAATKTFLAQVTAN CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCEEEEECCCCCCCHHHHHHHHHHHHHH YIVGLALAQARGTKYPDEVAREYHELEAMPELIERVISQMDPVADLARQYAQSSSILFLG HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEE RHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVIVVMPSPKGMGLLHS CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHH KLLSNIREIQARGARTIVIAEEGDETIRPYADHLIEIPAVSTLYQPLLSTIPMQVFAAAV HHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHH AQARGYDVDKPRNLAKSVTVE HHHCCCCCCCCHHHHHHCCCC >Mature Secondary Structure MCGIVGYVGHRDALSVVLEALRRLEYRGYDSAGVALADGHGGLLVQRKAGRLANLESAIA CCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHH ESGESFAATTGMGHTRWATHGAPTDRNAHPHQDATGKVAVVHNGIIENFAVLRAELESAG HCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCC VEFASDTDSEVAVHLVSRQFESGDTAGDFVASVQSVVRRLEGHFTLVFSHADDPGTIVAA CEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEE RRSTPLVVGIGDGEMFLGSDVAAFIEYTRDAVELGQDQVVVITADGYRITDFEGNDDTGN ECCCCEEEEECCCCEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCCC ARVFTIDWDLSAAEKGGYEYFMLKEIAEQPAAVSDTLLGHFDLDRIVLDEQRLSDQELRD EEEEEEECCCCHHCCCCCEEEHHHHHHHCCCHHHHHHHCCCCCHHHEECHHHCCHHHHHH IDKVFVVACGTAFHSGLLAKYAIEHWTRLPVEIELASEFRYRDPVLDRSTLVVAISQSGE HHHHHHEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCC TADTLEAVRHAKEQKAKVLAVCNTNGSQIPRECDAVLYTRAGPEIGVAATKTFLAQVTAN CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHCEEEEECCCCCCCHHHHHHHHHHHHHH YIVGLALAQARGTKYPDEVAREYHELEAMPELIERVISQMDPVADLARQYAQSSSILFLG HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEE RHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEGLPVIVVMPSPKGMGLLHS CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHH KLLSNIREIQARGARTIVIAEEGDETIRPYADHLIEIPAVSTLYQPLLSTIPMQVFAAAV HHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHH AQARGYDVDKPRNLAKSVTVE HHHCCCCCCCCHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA