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The map label for this gene is alr [H]

Identifier: 169630818

GI number: 169630818

Start: 3791911

End: 3793128

Strand: Reverse

Name: alr [H]

Synonym: MAB_3739c

Alternate gene names: 169630818

Gene position: 3793128-3791911 (Counterclockwise)

Preceding gene: 169630819

Following gene: 169630817

Centisome position: 74.86

GC content: 67.57

Gene sequence:

>1218_bases
ATGGGGCCGGTGAGCACGACTTCGACGACAACCGACGGCCTTCCGCCGAGCACCGGTGCGACGACCGCGCAAGCGGTCAT
CGACCTCGGCGCCATCGCGCACAACGTCAAGTTACTGCGTGAGCACGCCGGTACGGCCCGTCTCATGACTGTGGTCAAGG
CCGACGGCTACGGGCACGGCGCGGTTCGGGTGGCACGAGCCGCGCTCGCTGCCGGTGCCGACGAGCTTGGCGTCACCTCC
ATCGCCGAGGCGCTGCAGATTCGCGCGGCCGGTCTCGACGCACCGCTGCTCGCCTGGCTGCACGCGCCGGGAGCCGACTA
TGCGGCCGCGCTGCATGCCGATGTCGAGGTGGCCGTGTCCTCGCTCGGACAGCTCGGTGAGCTGCTTGCGGCGGCGCGAT
CCACCGGGCGCCAGGCGATCACGTCCATCAAGGTGGATACCGGACTGAATCGCAATGGAGTGCCTGCCGGGTACACCCGC
GATCTCTTCGAAGCGTTGGCCAAGGCGCAGGCCGAGGAGTCGATTCGGTTGCGCGGCATCATGTCCCACTTCGCGTATGC
CGACCAGCCGGGCCATCCCACCGTCGACATGCAGATCGGGCGGTTCAACGAGGCACTTGAGCTGGCACGCGGCTTCGGAT
TGCGTTATGAGCTGGCGCACCTGTCGAATTCGGCGGCCACTCTCACCCGTCCCGATGCGCGGTACGACATGGTGCGCCCC
GGTATCGCGGTATACGGCATCAACCCGCTTGGAGCCGCGGAGTCGGCGACATCCAACCGCGGCCGGACTTCCTTTGACCT
GATTCCGGCGATGTCGCTGACCTGCGCGGTGTCCTCGGTCAAGCCGGTGTCGGCCGGTGAGGGTGTGTCCTACGGGCACG
TGTGGACCGCCCCACGCGACACCAACGCCGCACTCATCGGAATCGGCTACGCCGACGGGGTGGTGCGCGCACTGGGCAAT
CGATTCGAGGTGGCCATCGGCGGACGCCGCTACCCCAATATCGGCCGGGTTTGCATGGACCAGTTCGTGGTTGACCTGGG
TGACAACGATGCCGGGGTGCAAGCCGGTGATGTGGCAACGCTTTTCGGGCCGGGAACAGGCGGCGAGCCGACCGCGCAGG
ACTGGGCGGAGCTGCTCGACACCATCGCCTACGAAGTGGTCACCGGCCCGCGGGGCAGGGTGGTGCGGACGTACCGGGAT
TCCAGGGCCGTTGAGTAA

Upstream 100 bases:

>100_bases
CGATGATCTCAACACCGTGCTCAAGGGACTCGACGAGCTGAAACCGAACGGACACTTCGACGAGGTGCAGCCGTTCGCTC
ATTAGCGTGCGGATGGGACA

Downstream 100 bases:

>100_bases
TAAGTCGAACGCCTGGCTGGCCGGTGTCGCGGGGCTCGGTGCGGTGGTTGCGGTGGCCGGTGTCGGCACCGCGCGCTCCA
TCGGCAGGCGCAGATTCGAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MGPVSTTSTTTDGLPPSTGATTAQAVIDLGAIAHNVKLLREHAGTARLMTVVKADGYGHGAVRVARAALAAGADELGVTS
IAEALQIRAAGLDAPLLAWLHAPGADYAAALHADVEVAVSSLGQLGELLAAARSTGRQAITSIKVDTGLNRNGVPAGYTR
DLFEALAKAQAEESIRLRGIMSHFAYADQPGHPTVDMQIGRFNEALELARGFGLRYELAHLSNSAATLTRPDARYDMVRP
GIAVYGINPLGAAESATSNRGRTSFDLIPAMSLTCAVSSVKPVSAGEGVSYGHVWTAPRDTNAALIGIGYADGVVRALGN
RFEVAIGGRRYPNIGRVCMDQFVVDLGDNDAGVQAGDVATLFGPGTGGEPTAQDWAELLDTIAYEVVTGPRGRVVRTYRD
SRAVE

Sequences:

>Translated_405_residues
MGPVSTTSTTTDGLPPSTGATTAQAVIDLGAIAHNVKLLREHAGTARLMTVVKADGYGHGAVRVARAALAAGADELGVTS
IAEALQIRAAGLDAPLLAWLHAPGADYAAALHADVEVAVSSLGQLGELLAAARSTGRQAITSIKVDTGLNRNGVPAGYTR
DLFEALAKAQAEESIRLRGIMSHFAYADQPGHPTVDMQIGRFNEALELARGFGLRYELAHLSNSAATLTRPDARYDMVRP
GIAVYGINPLGAAESATSNRGRTSFDLIPAMSLTCAVSSVKPVSAGEGVSYGHVWTAPRDTNAALIGIGYADGVVRALGN
RFEVAIGGRRYPNIGRVCMDQFVVDLGDNDAGVQAGDVATLFGPGTGGEPTAQDWAELLDTIAYEVVTGPRGRVVRTYRD
SRAVE
>Mature_404_residues
GPVSTTSTTTDGLPPSTGATTAQAVIDLGAIAHNVKLLREHAGTARLMTVVKADGYGHGAVRVARAALAAGADELGVTSI
AEALQIRAAGLDAPLLAWLHAPGADYAAALHADVEVAVSSLGQLGELLAAARSTGRQAITSIKVDTGLNRNGVPAGYTRD
LFEALAKAQAEESIRLRGIMSHFAYADQPGHPTVDMQIGRFNEALELARGFGLRYELAHLSNSAATLTRPDARYDMVRPG
IAVYGINPLGAAESATSNRGRTSFDLIPAMSLTCAVSSVKPVSAGEGVSYGHVWTAPRDTNAALIGIGYADGVVRALGNR
FEVAIGGRRYPNIGRVCMDQFVVDLGDNDAGVQAGDVATLFGPGTGGEPTAQDWAELLDTIAYEVVTGPRGRVVRTYRDS
RAVE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=381, Percent_Identity=34.3832020997375, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787439, Length=327, Percent_Identity=33.6391437308869, Blast_Score=132, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42142; Mature: 42011

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVSTTSTTTDGLPPSTGATTAQAVIDLGAIAHNVKLLREHAGTARLMTVVKADGYGHG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCH
AVRVARAALAAGADELGVTSIAEALQIRAAGLDAPLLAWLHAPGADYAAALHADVEVAVS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
SLGQLGELLAAARSTGRQAITSIKVDTGLNRNGVPAGYTRDLFEALAKAQAEESIRLRGI
HHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MSHFAYADQPGHPTVDMQIGRFNEALELARGFGLRYELAHLSNSAATLTRPDARYDMVRP
HHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCHHHHCC
GIAVYGINPLGAAESATSNRGRTSFDLIPAMSLTCAVSSVKPVSAGEGVSYGHVWTAPRD
CEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCC
TNAALIGIGYADGVVRALGNRFEVAIGGRRYPNIGRVCMDQFVVDLGDNDAGVQAGDVAT
CCEEEEEECHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
LFGPGTGGEPTAQDWAELLDTIAYEVVTGPRGRVVRTYRDSRAVE
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
GPVSTTSTTTDGLPPSTGATTAQAVIDLGAIAHNVKLLREHAGTARLMTVVKADGYGHG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCH
AVRVARAALAAGADELGVTSIAEALQIRAAGLDAPLLAWLHAPGADYAAALHADVEVAVS
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHH
SLGQLGELLAAARSTGRQAITSIKVDTGLNRNGVPAGYTRDLFEALAKAQAEESIRLRGI
HHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MSHFAYADQPGHPTVDMQIGRFNEALELARGFGLRYELAHLSNSAATLTRPDARYDMVRP
HHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCHHHHCC
GIAVYGINPLGAAESATSNRGRTSFDLIPAMSLTCAVSSVKPVSAGEGVSYGHVWTAPRD
CEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCC
TNAALIGIGYADGVVRALGNRFEVAIGGRRYPNIGRVCMDQFVVDLGDNDAGVQAGDVAT
CCEEEEEECHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEE
LFGPGTGGEPTAQDWAELLDTIAYEVVTGPRGRVVRTYRDSRAVE
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA