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The map label for this gene is rihA [H]

Identifier: 169630790

GI number: 169630790

Start: 3765654

End: 3766685

Strand: Direct

Name: rihA [H]

Synonym: MAB_3711

Alternate gene names: 169630790

Gene position: 3765654-3766685 (Clockwise)

Preceding gene: 169630789

Following gene: 169630795

Centisome position: 74.31

GC content: 62.4

Gene sequence:

>1032_bases
ATGGTTCCCGTTTTTGCCGACGTCGATACCGGAGTGGATGACGCACTGGGATTGATCTATCTCCTCGCTAGCGAGGATGC
GGAGATTGTCGGTATCGCTTCTACTGCGGGCAATGTCTCGGTAGACCATGTTTGCGCGAACAATCTGGGCCTGCTGGAGC
TATGTAAGGCACCACAGATTCCGGTGTCCAAAGGTGTCGCCGAACCATTGAGCGCGGCGCTGCGCACCGCGGAAGATACC
CACGGCCCCACTGGGCTCGGGTATGCCTTGCTGCCGGAATCCACCCGCACACTCACCGATTACGACTCGGCCGAGGCCTG
GGTGAAGGCCGCGCACGCATACCCCGGAGAGCTAGTAGGTCTGGCGACCGGCCCGCTGACCAATCTGGCGCTAGCCCTGC
GCACCGAACCCGAGTTGCCCAAACTCCTCAAACGGCTTGTGATCATGGGCGGCTCGTTCGACTACCCCGGCAACACCACT
CCAGTAGCGGAATGGAACGTCGTCGTGGATCCCGGTGCCACGGCGGAGGTGTACGCCGCGTGGGGAGCCGCGGGCGTACA
AGAACTTCCGATCGTGTGCGGCCTGAATCTCACCGAAACGATCGCCATGACACCGGAACATCTGGTCAGGCTGGCCGATG
CCGCCGGTGCCACCACCACCCCCCTGTCGGTACTCGACTCTCCGTCGAGCCGATCGGGAGCGAGCAACTCGTTGCTGCGT
TTCATCGAGGATGCCGCGCATTTCTACTTCGAATTCCACATGAAGCAGGGCGAAGGCTTCCTGGCGCATATGCACGATCC
CTTCGCCGCCGCGGTGGCGCTGGACCCATCACTTGTCCAAACCCGTTCCGCAACCGTCGATGTCGAGCTGACGGGGGATC
TGACGCGTGCGATGACCATTGCGGACTGGAAGGGACAGTGGGGACAGCGGCCCAACGCGCAGATCGCGGTGGAGACCGAT
CCCGAAGTGTTCTTCCAGCGGTTCATCGAGCGCGTGAGCGTATTCGCGCGCACAGTCGATGACGCCCGCTGA

Upstream 100 bases:

>100_bases
TCCCAACAGCAGATTAAGTCAGTCGTATGACTGTTACCATGGCACGCTCTGCCGCTTGTCGAATCCGTGCACAGAGCTAA
CCGGCGGTAGGTTGACGTCC

Downstream 100 bases:

>100_bases
CCCCGTCCGTCATTCATATACACCCTCCACATACCAACGTTGCCTGCGGAAATGCAGGAGCAGCGCCTGGCCGCCGCCGC
TACTTTCGAGCAGCACCTGG

Product: putative nucleoside hydrolase IunH

Products: NA

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MVPVFADVDTGVDDALGLIYLLASEDAEIVGIASTAGNVSVDHVCANNLGLLELCKAPQIPVSKGVAEPLSAALRTAEDT
HGPTGLGYALLPESTRTLTDYDSAEAWVKAAHAYPGELVGLATGPLTNLALALRTEPELPKLLKRLVIMGGSFDYPGNTT
PVAEWNVVVDPGATAEVYAAWGAAGVQELPIVCGLNLTETIAMTPEHLVRLADAAGATTTPLSVLDSPSSRSGASNSLLR
FIEDAAHFYFEFHMKQGEGFLAHMHDPFAAAVALDPSLVQTRSATVDVELTGDLTRAMTIADWKGQWGQRPNAQIAVETD
PEVFFQRFIERVSVFARTVDDAR

Sequences:

>Translated_343_residues
MVPVFADVDTGVDDALGLIYLLASEDAEIVGIASTAGNVSVDHVCANNLGLLELCKAPQIPVSKGVAEPLSAALRTAEDT
HGPTGLGYALLPESTRTLTDYDSAEAWVKAAHAYPGELVGLATGPLTNLALALRTEPELPKLLKRLVIMGGSFDYPGNTT
PVAEWNVVVDPGATAEVYAAWGAAGVQELPIVCGLNLTETIAMTPEHLVRLADAAGATTTPLSVLDSPSSRSGASNSLLR
FIEDAAHFYFEFHMKQGEGFLAHMHDPFAAAVALDPSLVQTRSATVDVELTGDLTRAMTIADWKGQWGQRPNAQIAVETD
PEVFFQRFIERVSVFARTVDDAR
>Mature_343_residues
MVPVFADVDTGVDDALGLIYLLASEDAEIVGIASTAGNVSVDHVCANNLGLLELCKAPQIPVSKGVAEPLSAALRTAEDT
HGPTGLGYALLPESTRTLTDYDSAEAWVKAAHAYPGELVGLATGPLTNLALALRTEPELPKLLKRLVIMGGSFDYPGNTT
PVAEWNVVVDPGATAEVYAAWGAAGVQELPIVCGLNLTETIAMTPEHLVRLADAAGATTTPLSVLDSPSSRSGASNSLLR
FIEDAAHFYFEFHMKQGEGFLAHMHDPFAAAVALDPSLVQTRSATVDVELTGDLTRAMTIADWKGQWGQRPNAQIAVETD
PEVFFQRFIERVSVFARTVDDAR

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=337, Percent_Identity=31.4540059347181, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786213, Length=326, Percent_Identity=33.7423312883436, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788486, Length=336, Percent_Identity=24.1071428571429, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32565474, Length=182, Percent_Identity=29.6703296703297, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320608, Length=306, Percent_Identity=31.3725490196078, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641839, Length=185, Percent_Identity=32.4324324324324, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641837, Length=148, Percent_Identity=33.7837837837838, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24583915, Length=187, Percent_Identity=31.5508021390374, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.-

Molecular weight: Translated: 36409; Mature: 36409

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVFADVDTGVDDALGLIYLLASEDAEIVGIASTAGNVSVDHVCANNLGLLELCKAPQI
CCCEEECCCCCHHHHHEEEEEEECCCCEEEEEEECCCCCEEHHHHCCCCCHHHHHCCCCC
PVSKGVAEPLSAALRTAEDTHGPTGLGYALLPESTRTLTDYDSAEAWVKAAHAYPGELVG
CHHCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCHHHHHHHHHHCCCCCEEE
LATGPLTNLALALRTEPELPKLLKRLVIMGGSFDYPGNTTPVAEWNVVVDPGATAEVYAA
ECCCCHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEH
WGAAGVQELPIVCGLNLTETIAMTPEHLVRLADAAGATTTPLSVLDSPSSRSGASNSLLR
HCCCCHHHCCEEECCCHHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHH
FIEDAAHFYFEFHMKQGEGFLAHMHDPFAAAVALDPSLVQTRSATVDVELTGDLTRAMTI
HHHHHHHEEEEEEEECCCCEEEECCCCCEEEEECCHHHHHCCCCEEEEEECCCHHHEEEE
ADWKGQWGQRPNAQIAVETDPEVFFQRFIERVSVFARTVDDAR
ECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVPVFADVDTGVDDALGLIYLLASEDAEIVGIASTAGNVSVDHVCANNLGLLELCKAPQI
CCCEEECCCCCHHHHHEEEEEEECCCCEEEEEEECCCCCEEHHHHCCCCCHHHHHCCCCC
PVSKGVAEPLSAALRTAEDTHGPTGLGYALLPESTRTLTDYDSAEAWVKAAHAYPGELVG
CHHCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEECCCCHHHHHHHHHHCCCCCEEE
LATGPLTNLALALRTEPELPKLLKRLVIMGGSFDYPGNTTPVAEWNVVVDPGATAEVYAA
ECCCCHHHEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEH
WGAAGVQELPIVCGLNLTETIAMTPEHLVRLADAAGATTTPLSVLDSPSSRSGASNSLLR
HCCCCHHHCCEEECCCHHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHHH
FIEDAAHFYFEFHMKQGEGFLAHMHDPFAAAVALDPSLVQTRSATVDVELTGDLTRAMTI
HHHHHHHEEEEEEEECCCCEEEECCCCCEEEEECCHHHHHCCCCEEEEEECCCHHHEEEE
ADWKGQWGQRPNAQIAVETDPEVFFQRFIERVSVFARTVDDAR
ECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA