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The map label for this gene is sdhB [H]

Identifier: 169630755

GI number: 169630755

Start: 3728705

End: 3729487

Strand: Direct

Name: sdhB [H]

Synonym: MAB_3676

Alternate gene names: 169630755

Gene position: 3728705-3729487 (Clockwise)

Preceding gene: 169630754

Following gene: 169630756

Centisome position: 73.59

GC content: 64.88

Gene sequence:

>783_bases
ATGACTGCGGTTATCGAGAAAGCCGAAGCAGGCGACCCGCCGCTGCCTCCGGTCCCCGAGGGCGCGGTCATGGTGGATCT
GAAGATCCAGCGTTTCAACCCCGAGGATCCCGACGCCGCGGGATGGCAGACGTTCCGGGTACCCTGCCTGCCCACGGACC
GGCTGTTGAACCTGCTGCTGTATGTGAAGGGCTACCTGGATGGCACCCTGACCTTCCGCCGGTCGTGCGCACATGGTGTG
TGCGGTTCGGACGCCATGCGGATCAACGGTGTGAACCGGCTGGCCTGCAAGGTGCTGATGCGGGACCTGCTGCCCAAGAA
TCCCAAGAAGACGCTCACCATCACCATCGAGCCGATCCGCGGCCTTCCCGTGGAGAAGGACCTCGTGGTCAACATGGAGC
CCTTCTTCGACGCCTACCGCGCGGTGAAGCCGTTCATGATCACCAGCGGCAACCAGCCCACGCGCGAGTACATCCAGAGC
CAGACCGACCGTGCGCGCTTCGATGACACCACCAAATGCATCCTGTGTGCCTGCTGCACCACCAGCTGCCCGGTGTTCTG
GAGCGACGGAAGCTACTTCGGCCCGGCCGCAATCGTCAACGCACACCGGTTCATCTTCGACAGCCGCGACGAGGCTGCCG
CGGAGCGCCTGGACATCCTCAACGACGTCGACGGGGTGTGGCGCTGCCGCACCACGTTCAACTGCACCGACGCCTGCCCG
CGCGGCATCGAGGTGACCAAGGCGATCCAGGAGGTCAAGCGCGCCCTGATGTTCGCGCGCTGA

Upstream 100 bases:

>100_bases
ATGGCGTACAAGCAGGGTGCCGAGCTGCTGTCCGACATCCGGCTGGACTACAAGCCCGTTGTCCAGACCCGGTACGAGCC
GATGGAACGGAAGTACTGAG

Downstream 100 bases:

>100_bases
CCGAGATCTACCCCCGCCGGGTGTGAGCATTCACCGCTCATGCCCGGCGGTTTTTTCTGCCCGGGATGCCCTGTCACACA
TCTGGGTGCTGCCTCGTCAT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTAVIEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDAAGWQTFRVPCLPTDRLLNLLLYVKGYLDGTLTFRRSCAHGV
CGSDAMRINGVNRLACKVLMRDLLPKNPKKTLTITIEPIRGLPVEKDLVVNMEPFFDAYRAVKPFMITSGNQPTREYIQS
QTDRARFDDTTKCILCACCTTSCPVFWSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCTDACP
RGIEVTKAIQEVKRALMFAR

Sequences:

>Translated_260_residues
MTAVIEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDAAGWQTFRVPCLPTDRLLNLLLYVKGYLDGTLTFRRSCAHGV
CGSDAMRINGVNRLACKVLMRDLLPKNPKKTLTITIEPIRGLPVEKDLVVNMEPFFDAYRAVKPFMITSGNQPTREYIQS
QTDRARFDDTTKCILCACCTTSCPVFWSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCTDACP
RGIEVTKAIQEVKRALMFAR
>Mature_259_residues
TAVIEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDAAGWQTFRVPCLPTDRLLNLLLYVKGYLDGTLTFRRSCAHGVC
GSDAMRINGVNRLACKVLMRDLLPKNPKKTLTITIEPIRGLPVEKDLVVNMEPFFDAYRAVKPFMITSGNQPTREYIQSQ
TDRARFDDTTKCILCACCTTSCPVFWSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCTDACPR
GIEVTKAIQEVKRALMFAR

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=41.1255411255411, Blast_Score=174, Evalue=9e-44,
Organism=Escherichia coli, GI1786943, Length=240, Percent_Identity=41.6666666666667, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1790596, Length=237, Percent_Identity=37.5527426160338, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17533915, Length=244, Percent_Identity=39.344262295082, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322987, Length=239, Percent_Identity=38.9121338912134, Blast_Score=174, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17137106, Length=239, Percent_Identity=41.0041841004184, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24643156, Length=236, Percent_Identity=38.9830508474576, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29056; Mature: 28925

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVIEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDAAGWQTFRVPCLPTDRLLNLLL
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHH
YVKGYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDLLPKNPKKTLTITIEPIR
HHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GLPVEKDLVVNMEPFFDAYRAVKPFMITSGNQPTREYIQSQTDRARFDDTTKCILCACCT
CCCCCCCEEEECHHHHHHHHHHCCEEEECCCCHHHHHHHCCCHHHCCCCHHHHHHEEHHC
TSCPVFWSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCTDACP
CCCCEEECCCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RGIEVTKAIQEVKRALMFAR
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAVIEKAEAGDPPLPPVPEGAVMVDLKIQRFNPEDPDAAGWQTFRVPCLPTDRLLNLLL
CCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHH
YVKGYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDLLPKNPKKTLTITIEPIR
HHHHHCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
GLPVEKDLVVNMEPFFDAYRAVKPFMITSGNQPTREYIQSQTDRARFDDTTKCILCACCT
CCCCCCCEEEECHHHHHHHHHHCCEEEECCCCHHHHHHHCCCHHHCCCCHHHHHHEEHHC
TSCPVFWSDGSYFGPAAIVNAHRFIFDSRDEAAAERLDILNDVDGVWRCRTTFNCTDACP
CCCCEEECCCCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
RGIEVTKAIQEVKRALMFAR
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA