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The map label for this gene is add

Identifier: 169630749

GI number: 169630749

Start: 3722990

End: 3724078

Strand: Reverse

Name: add

Synonym: MAB_3670c

Alternate gene names: 169630749

Gene position: 3724078-3722990 (Counterclockwise)

Preceding gene: 169630750

Following gene: 169630741

Centisome position: 73.49

GC content: 65.11

Gene sequence:

>1089_bases
GTGACGGCCGAACTTGATTTGGTGTCAATCACCCAGGCTCCCAAAGCGCTACTGCATGATCATCTGGACGGGGGTTTGCG
ACCAGGCACCGTCCTGGACCTAGCCCGCGAAACCGGGTACGAAAACCTGCCGGCGCAGGACGAAACCGCCCTGGCCTCAT
GGTTCCGGACCGCCGCCGACAGTGGCTCGCTGGAGCAGTATCTGGAGACCTTTGCACACACGGTGGGTGTCATGCAGACG
GCGTCCGCGCTGCATCGCGTGGCCGCCGAATGCGTCGAAGACCTCGCCGCCGATGGCGTGGTGTACGCCGAGGTCCGCTT
TGCGCCGGAGCTGCACATCGACGCTGGCCTCACTCTTGACGACGTCATGGATGCCGTGCTGGCCGGGTTCGCCGACGGGG
AGCGGCAAGCCAGTGCCGCGGGCAAGCGCATCAAGGTGCGTACCTTGGTCACCGCGATGCGGCACGCCGCGCGATCACGG
GAGATCGCCGAGCTGGCCGTGAAGTTCCGCGACCGGGGTGCCGTCGGGTTCGACATCGCCGGCGCCGAGGCCGGATATCC
GCCGACCCGTCATCTGGACGCCTTCGAGTACATGCGGAACGCCAACTCCCGGTTCACGATCCATGCCGGCGAGGGATTCG
GATTGCCCTCGATCCATGAGGCGATCGCCTTCTGCGGTGCCGACCGGCTGGGCCACGGGGTGCGCATCGTCGACGACATC
GACATCGGCCCCGACGGCACGGCACATTTGGGCAGACTCTCCTCGCTGCTGCGCGACAAGCGGGTGCCGTTAGAACTGTG
CCCGAGTTCGAATGTGCAGACCGGTGCTGTCGAAAGCCTGGCCGACCATCCCTTCGATCTGCTGGCGCGATTGCGGTTCC
GGGTGACGGTGAACACCGACAACCGGCTGATGAGCGACACCACGATGAGCCGCGAGATGCTGCGCCTGGTCGAGACGTTC
GGGTACGGCTGGAGCGATCTGCAGCGATTCACCATCAACGCGATGAAGTCCGCCTTCATCCCGTTCGATGAGCGGTTGGC
CATCATCGATGACGTGATCAAGCCCGGGTACGCGGTCCTGATCGGCTAG

Upstream 100 bases:

>100_bases
CCCAGGAGCGATTGCCCGCCGCGCTCGACGCGCTGGAAGGTGGGTGGGAGATCGGTGCGGCACCGACCGCTACCCCCCTC
ATCATCGATAGACTTCCGGT

Downstream 100 bases:

>100_bases
CGGCGCACTATTCGCGCCGCAGCCGCGCCTCCATCGCCCGCTCCAGGGTGCGCCAACGTTCGGCGGCGTCGACGAACGGG
CCCTTCGGTTCGTCGTGCTT

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTAELDLVSITQAPKALLHDHLDGGLRPGTVLDLARETGYENLPAQDETALASWFRTAADSGSLEQYLETFAHTVGVMQT
ASALHRVAAECVEDLAADGVVYAEVRFAPELHIDAGLTLDDVMDAVLAGFADGERQASAAGKRIKVRTLVTAMRHAARSR
EIAELAVKFRDRGAVGFDIAGAEAGYPPTRHLDAFEYMRNANSRFTIHAGEGFGLPSIHEAIAFCGADRLGHGVRIVDDI
DIGPDGTAHLGRLSSLLRDKRVPLELCPSSNVQTGAVESLADHPFDLLARLRFRVTVNTDNRLMSDTTMSREMLRLVETF
GYGWSDLQRFTINAMKSAFIPFDERLAIIDDVIKPGYAVLIG

Sequences:

>Translated_362_residues
MTAELDLVSITQAPKALLHDHLDGGLRPGTVLDLARETGYENLPAQDETALASWFRTAADSGSLEQYLETFAHTVGVMQT
ASALHRVAAECVEDLAADGVVYAEVRFAPELHIDAGLTLDDVMDAVLAGFADGERQASAAGKRIKVRTLVTAMRHAARSR
EIAELAVKFRDRGAVGFDIAGAEAGYPPTRHLDAFEYMRNANSRFTIHAGEGFGLPSIHEAIAFCGADRLGHGVRIVDDI
DIGPDGTAHLGRLSSLLRDKRVPLELCPSSNVQTGAVESLADHPFDLLARLRFRVTVNTDNRLMSDTTMSREMLRLVETF
GYGWSDLQRFTINAMKSAFIPFDERLAIIDDVIKPGYAVLIG
>Mature_361_residues
TAELDLVSITQAPKALLHDHLDGGLRPGTVLDLARETGYENLPAQDETALASWFRTAADSGSLEQYLETFAHTVGVMQTA
SALHRVAAECVEDLAADGVVYAEVRFAPELHIDAGLTLDDVMDAVLAGFADGERQASAAGKRIKVRTLVTAMRHAARSRE
IAELAVKFRDRGAVGFDIAGAEAGYPPTRHLDAFEYMRNANSRFTIHAGEGFGLPSIHEAIAFCGADRLGHGVRIVDDID
IGPDGTAHLGRLSSLLRDKRVPLELCPSSNVQTGAVESLADHPFDLLARLRFRVTVNTDNRLMSDTTMSREMLRLVETFG
YGWSDLQRFTINAMKSAFIPFDERLAIIDDVIKPGYAVLIG

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family

Homologues:

Organism=Homo sapiens, GI47078295, Length=360, Percent_Identity=29.4444444444444, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1787910, Length=343, Percent_Identity=30.9037900874636, Blast_Score=147, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=355, Percent_Identity=29.8591549295775, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17538512, Length=355, Percent_Identity=29.8591549295775, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324188, Length=303, Percent_Identity=24.4224422442244, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24645260, Length=347, Percent_Identity=25.6484149855908, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADD_MYCA9 (B1MFZ9)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001704398.1
- ProteinModelPortal:   B1MFZ9
- SMR:   B1MFZ9
- EnsemblBacteria:   EBMYCT00000005781
- GeneID:   5966168
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_3670c
- GeneTree:   EBGT00050000016615
- HOGENOM:   HBG630382
- OMA:   PYYMAMN
- ProtClustDB:   PRK09358
- BioCyc:   MABS561007:MAB_3670C-MONOMER
- HAMAP:   MF_00540
- InterPro:   IPR001365
- InterPro:   IPR006330
- PANTHER:   PTHR11409
- TIGRFAMs:   TIGR01430

Pfam domain/function: PF00962 A_deaminase

EC number: =3.5.4.4

Molecular weight: Translated: 39375; Mature: 39244

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00485 A_DEAMINASE

Important sites: ACT_SITE 211-211 BINDING 21-21 BINDING 23-23 BINDING 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAELDLVSITQAPKALLHDHLDGGLRPGTVLDLARETGYENLPAQDETALASWFRTAAD
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
SGSLEQYLETFAHTVGVMQTASALHRVAAECVEDLAADGVVYAEVRFAPELHIDAGLTLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCCCCHH
DVMDAVLAGFADGERQASAAGKRIKVRTLVTAMRHAARSREIAELAVKFRDRGAVGFDIA
HHHHHHHHHCCCCHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GAEAGYPPTRHLDAFEYMRNANSRFTIHAGEGFGLPSIHEAIAFCGADRLGHGVRIVDDI
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCHHHHCCCEEEEEEC
DIGPDGTAHLGRLSSLLRDKRVPLELCPSSNVQTGAVESLADHPFDLLARLRFRVTVNTD
CCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHCCCHHHHHHEEEEEEECCC
NRLMSDTTMSREMLRLVETFGYGWSDLQRFTINAMKSAFIPFDERLAIIDDVIKPGYAVL
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEE
IG
EC
>Mature Secondary Structure 
TAELDLVSITQAPKALLHDHLDGGLRPGTVLDLARETGYENLPAQDETALASWFRTAAD
CCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
SGSLEQYLETFAHTVGVMQTASALHRVAAECVEDLAADGVVYAEVRFAPELHIDAGLTLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCCCCHH
DVMDAVLAGFADGERQASAAGKRIKVRTLVTAMRHAARSREIAELAVKFRDRGAVGFDIA
HHHHHHHHHCCCCHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
GAEAGYPPTRHLDAFEYMRNANSRFTIHAGEGFGLPSIHEAIAFCGADRLGHGVRIVDDI
CCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCHHHHCCCEEEEEEC
DIGPDGTAHLGRLSSLLRDKRVPLELCPSSNVQTGAVESLADHPFDLLARLRFRVTVNTD
CCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHCCCHHHHHHEEEEEEECCC
NRLMSDTTMSREMLRLVETFGYGWSDLQRFTINAMKSAFIPFDERLAIIDDVIKPGYAVL
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEE
IG
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA