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The map label for this gene is mpg1 [H]

Identifier: 169630691

GI number: 169630691

Start: 3660675

End: 3661754

Strand: Reverse

Name: mpg1 [H]

Synonym: MAB_3611c

Alternate gene names: 169630691

Gene position: 3661754-3660675 (Counterclockwise)

Preceding gene: 169630692

Following gene: 169630690

Centisome position: 72.26

GC content: 64.35

Gene sequence:

>1080_bases
ATGTCTGGCACTGTGAAAGCCGATGCCGTCATCTTGGTGGGTGGGCAGGGTACCCGGTTGCGTCCGCTGACCTTGTCGGC
GCCCAAACCGATGTTGCCGATCGCGGGTTTTCCGTTTCTTACCCACGTGTTGTCCCGCGTTGCCGCCGCAGGCATTGATC
ACGTCGTGCTCGGCACGTCCTACAAGGCCGATGTCTTCGAGTCGGAGTTCGGCGATGGATCCAAGCTCGGCCTACAGATC
ACGTACGTGTACGAAGAGGAGCCGCTGGGTACCGGCGGTGCCATCCGAAATGTGTTGGAGCATCTGAGGTACGACACCGC
GCTGATCTTCAACGGCGATGTGCTCTCCGGCTTGGATCTGAAAGATCTTCTCGCACAGCATGAACAGACCCAGGCCGACC
TCACCTTGCATTTGGTACGCGTCGGCGATCCGCGCGCATTCGGTTGTGTGCCCACCGATTCCGATGGCAAGGTCACCGCA
TTCCTGGAGAAGACCGAGGACCCGCCCACTGATCAGATCAACGCCGGTTGTTACGTCTTCCGGCGTGAGCTGATTGAGCA
GATCCCGTCGGGTCGGCCCGTTTCGGTTGAGCGGGAGGTATTCCCGGGTCTGTTGAGCAGCGGAGCCAAGGTATGTGGGT
ATGTCGACACCAGTTACTGGCGAGACATGGGAACCCCGGAAGACTTTGTGCGTGGGTCGGCCGACCTGGTGCGCGGCATT
GCGCCCTCGCCGGCCATCCCCGAGCATCCGGGCGAGGCGCTGGTGCACGACGGCGCGTCGGTGGCCCCGGGCGCGCTGGT
CATCGGCGGTACCGTGGTGGGCCGCGGTGCCGAAATCGGCCCGGGTGCGCGGCTGGACGGCGCGGTTGTTTTCGACGGTG
CGCGCATAGAGGCCGGGGCCGTCGTGGAACGTTCTATCATCGGGTTCGGCGCCCGGATCGGACCACGCGCTCTGGTGCGT
GACGGCGTGATCGGGGACGGCGCCGATATCGGCGCACGGTGCGAGCTGCTGCGCGGCGCGCGGGTGTGGCCCGGCATCAC
GATCCCCGATGGCGGTATCAGGTACTCGTCGGACGTATAA

Upstream 100 bases:

>100_bases
TTGCGCTGGAGCATTCGGGGCGCGCTGGCGGCCCGATCTGCGATTGTGGTGCGTGCGGCCATCCGCGCCAATCGGCGCCG
GGATAAGCAAGGAGGGTGAT

Downstream 100 bases:

>100_bases
GCAATGCGCTGTGGCGGGTTGTTGGCTTGCGGGACAGTGCTTCTTGCGCTGATCGGCTGCTCGGACAGGGGCGATCAGAA
GCAGCAGGAGCAGGATCTGC

Product: putative sugar-phosphate nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSGTVKADAVILVGGQGTRLRPLTLSAPKPMLPIAGFPFLTHVLSRVAAAGIDHVVLGTSYKADVFESEFGDGSKLGLQI
TYVYEEEPLGTGGAIRNVLEHLRYDTALIFNGDVLSGLDLKDLLAQHEQTQADLTLHLVRVGDPRAFGCVPTDSDGKVTA
FLEKTEDPPTDQINAGCYVFRRELIEQIPSGRPVSVEREVFPGLLSSGAKVCGYVDTSYWRDMGTPEDFVRGSADLVRGI
APSPAIPEHPGEALVHDGASVAPGALVIGGTVVGRGAEIGPGARLDGAVVFDGARIEAGAVVERSIIGFGARIGPRALVR
DGVIGDGADIGARCELLRGARVWPGITIPDGGIRYSSDV

Sequences:

>Translated_359_residues
MSGTVKADAVILVGGQGTRLRPLTLSAPKPMLPIAGFPFLTHVLSRVAAAGIDHVVLGTSYKADVFESEFGDGSKLGLQI
TYVYEEEPLGTGGAIRNVLEHLRYDTALIFNGDVLSGLDLKDLLAQHEQTQADLTLHLVRVGDPRAFGCVPTDSDGKVTA
FLEKTEDPPTDQINAGCYVFRRELIEQIPSGRPVSVEREVFPGLLSSGAKVCGYVDTSYWRDMGTPEDFVRGSADLVRGI
APSPAIPEHPGEALVHDGASVAPGALVIGGTVVGRGAEIGPGARLDGAVVFDGARIEAGAVVERSIIGFGARIGPRALVR
DGVIGDGADIGARCELLRGARVWPGITIPDGGIRYSSDV
>Mature_358_residues
SGTVKADAVILVGGQGTRLRPLTLSAPKPMLPIAGFPFLTHVLSRVAAAGIDHVVLGTSYKADVFESEFGDGSKLGLQIT
YVYEEEPLGTGGAIRNVLEHLRYDTALIFNGDVLSGLDLKDLLAQHEQTQADLTLHLVRVGDPRAFGCVPTDSDGKVTAF
LEKTEDPPTDQINAGCYVFRRELIEQIPSGRPVSVEREVFPGLLSSGAKVCGYVDTSYWRDMGTPEDFVRGSADLVRGIA
PSPAIPEHPGEALVHDGASVAPGALVIGGTVVGRGAEIGPGARLDGAVVFDGARIEAGAVVERSIIGFGARIGPRALVRD
GVIGDGADIGARCELLRGARVWPGITIPDGGIRYSSDV

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=359, Percent_Identity=32.3119777158774, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI11761619, Length=347, Percent_Identity=31.700288184438, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI31881779, Length=397, Percent_Identity=25.9445843828715, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI45447090, Length=397, Percent_Identity=25.9445843828715, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1788351, Length=235, Percent_Identity=28.5106382978723, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790224, Length=186, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789837, Length=392, Percent_Identity=24.234693877551, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=356, Percent_Identity=33.4269662921348, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17509979, Length=325, Percent_Identity=28, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17509981, Length=316, Percent_Identity=26.5822784810127, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320148, Length=355, Percent_Identity=29.5774647887324, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355443, Length=352, Percent_Identity=32.1022727272727, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24644084, Length=352, Percent_Identity=32.1022727272727, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24653912, Length=370, Percent_Identity=26.7567567567568, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 37685; Mature: 37554

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTVKADAVILVGGQGTRLRPLTLSAPKPMLPIAGFPFLTHVLSRVAAAGIDHVVLGTS
CCCCEEECEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
YKADVFESEFGDGSKLGLQITYVYEEEPLGTGGAIRNVLEHLRYDTALIFNGDVLSGLDL
CCCHHHHHCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCEECCCCH
KDLLAQHEQTQADLTLHLVRVGDPRAFGCVPTDSDGKVTAFLEKTEDPPTDQINAGCYVF
HHHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHH
RRELIEQIPSGRPVSVEREVFPGLLSSGAKVCGYVDTSYWRDMGTPEDFVRGSADLVRGI
HHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEEEECHHHHHCCCCHHHHHCCCHHHHHCC
APSPAIPEHPGEALVHDGASVAPGALVIGGTVVGRGAEIGPGARLDGAVVFDGARIEAGA
CCCCCCCCCCCCCEEECCCCCCCCEEEECCEEEECCCCCCCCCCCCCEEEECCCEECCCH
VVERSIIGFGARIGPRALVRDGVIGDGADIGARCELLRGARVWPGITIPDGGIRYSSDV
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCCEEECCCC
>Mature Secondary Structure 
SGTVKADAVILVGGQGTRLRPLTLSAPKPMLPIAGFPFLTHVLSRVAAAGIDHVVLGTS
CCCEEECEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCC
YKADVFESEFGDGSKLGLQITYVYEEEPLGTGGAIRNVLEHLRYDTALIFNGDVLSGLDL
CCCHHHHHCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCEECCCCH
KDLLAQHEQTQADLTLHLVRVGDPRAFGCVPTDSDGKVTAFLEKTEDPPTDQINAGCYVF
HHHHHHHHCCCCCEEEEEEEECCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHH
RRELIEQIPSGRPVSVEREVFPGLLSSGAKVCGYVDTSYWRDMGTPEDFVRGSADLVRGI
HHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEEEECHHHHHCCCCHHHHHCCCHHHHHCC
APSPAIPEHPGEALVHDGASVAPGALVIGGTVVGRGAEIGPGARLDGAVVFDGARIEAGA
CCCCCCCCCCCCCEEECCCCCCCCEEEECCEEEECCCCCCCCCCCCCEEEECCCEECCCH
VVERSIIGFGARIGPRALVRDGVIGDGADIGARCELLRGARVWPGITIPDGGIRYSSDV
HHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCEECCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]