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The map label for this gene is tmk [H]

Identifier: 169630674

GI number: 169630674

Start: 3644441

End: 3645079

Strand: Reverse

Name: tmk [H]

Synonym: MAB_3594c

Alternate gene names: 169630674

Gene position: 3645079-3644441 (Counterclockwise)

Preceding gene: 169630675

Following gene: 169630672

Centisome position: 71.94

GC content: 66.04

Gene sequence:

>639_bases
GTGGGCCAGCTGATTGCGATCGAGGGCGTGGACGGCGCCGGTAAGCGCACGCTGACAGAGAAGTTGATAGCGCGCGGCAA
CTCCCAGGGGTTATCCGTTGCGACGCTGGACTTCCCGCGTTACGGGCGTTCGGTGCATGCCGACCTCGCTGCCGAGTCGC
TCAAAGGTGGACACGGCGATGTGGTGTCGTCCGCGTACGCGATGGGTCTGCTGTTCGCGCTGGATCGGCGTGATGCAAGG
GACGAGCTGGCGGGGCTGACCCGCTCTCATGACCTGGTGATCTTAGATCGGTGGGTGGCTTCCAACGCCGCGTACGGTGC
GGCCCGGCTGCATCAGGACGGTGGCGGCGACATGGCGCGCTGGGTGCACCAACTCGAGTATGAGCGCTTCGGGCTGCCGC
ATCCGGACTGGCAGGTTTTCCTTGACGTTTCTCCGGAGCTGGCCCAGCAGCGCGCCCGTCAGCGCGAACAACAGGAGAGC
GACCGCGCTCGCGACACCTACGAGCGTGACTCGGATCTACAGCAGCGGGTATCGGCAGCGTATGCCGATCTGGCGCAGCG
TGACTGGGGCGGCCCCTGGATGATCACGGACGGTGTCGAGCCGGAGGCATTGGCGGCCCAACTACTTCGCCGAGCGTGA

Upstream 100 bases:

>100_bases
GTCCCTACAAGCCGGAGCACTACCGCTACTGATCGCCGCCAATCCACGTAGAGGCCCCTTGCACTTCGGTGCCGGGGGCC
TTTGCGTAGGCTGACCAGCC

Downstream 100 bases:

>100_bases
AGCTACTGCGGTCAAGCGGCGGAAATTCCGCAATGGCTTCACATTCGACGAGCAGCGGTGCGGCGCTTACCATTCGCTGG
CTTCGACCTCTTCCTCGCGA

Product: thymidylate kinase

Products: NA

Alternate protein names: Thymidine monophosphate kinase; dTMP kinase; TMPK [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MGQLIAIEGVDGAGKRTLTEKLIARGNSQGLSVATLDFPRYGRSVHADLAAESLKGGHGDVVSSAYAMGLLFALDRRDAR
DELAGLTRSHDLVILDRWVASNAAYGAARLHQDGGGDMARWVHQLEYERFGLPHPDWQVFLDVSPELAQQRARQREQQES
DRARDTYERDSDLQQRVSAAYADLAQRDWGGPWMITDGVEPEALAAQLLRRA

Sequences:

>Translated_212_residues
MGQLIAIEGVDGAGKRTLTEKLIARGNSQGLSVATLDFPRYGRSVHADLAAESLKGGHGDVVSSAYAMGLLFALDRRDAR
DELAGLTRSHDLVILDRWVASNAAYGAARLHQDGGGDMARWVHQLEYERFGLPHPDWQVFLDVSPELAQQRARQREQQES
DRARDTYERDSDLQQRVSAAYADLAQRDWGGPWMITDGVEPEALAAQLLRRA
>Mature_211_residues
GQLIAIEGVDGAGKRTLTEKLIARGNSQGLSVATLDFPRYGRSVHADLAAESLKGGHGDVVSSAYAMGLLFALDRRDARD
ELAGLTRSHDLVILDRWVASNAAYGAARLHQDGGGDMARWVHQLEYERFGLPHPDWQVFLDVSPELAQQRARQREQQESD
RARDTYERDSDLQQRVSAAYADLAQRDWGGPWMITDGVEPEALAAQLLRRA

Specific function: Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018095
- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 23466; Mature: 23335

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLIAIEGVDGAGKRTLTEKLIARGNSQGLSVATLDFPRYGRSVHADLAAESLKGGHGD
CCCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCH
VVSSAYAMGLLFALDRRDARDELAGLTRSHDLVILDRWVASNAAYGAARLHQDGGGDMAR
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHHHHCCCCHHHHHHCCCCCCHHHH
WVHQLEYERFGLPHPDWQVFLDVSPELAQQRARQREQQESDRARDTYERDSDLQQRVSAA
HHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
YADLAQRDWGGPWMITDGVEPEALAAQLLRRA
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GQLIAIEGVDGAGKRTLTEKLIARGNSQGLSVATLDFPRYGRSVHADLAAESLKGGHGD
CCEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCH
VVSSAYAMGLLFALDRRDARDELAGLTRSHDLVILDRWVASNAAYGAARLHQDGGGDMAR
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEHHHHCCCCHHHHHHCCCCCCHHHH
WVHQLEYERFGLPHPDWQVFLDVSPELAQQRARQREQQESDRARDTYERDSDLQQRVSAA
HHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
YADLAQRDWGGPWMITDGVEPEALAAQLLRRA
HHHHHHHCCCCCEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 11369858; 10666613; 11469859; 11914484; 12454011; 12662932 [H]