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The map label for this gene is kstR2 [H]

Identifier: 169630666

GI number: 169630666

Start: 3634435

End: 3635127

Strand: Reverse

Name: kstR2 [H]

Synonym: MAB_3586c

Alternate gene names: 169630666

Gene position: 3635127-3634435 (Counterclockwise)

Preceding gene: 169630667

Following gene: 169630665

Centisome position: 71.74

GC content: 64.79

Gene sequence:

>693_bases
GTGCCTCGTGTGGTGAAACATCCGGAACTGCGCCGGACCGAATTGCTGGATCTGGCGATGACCCTATTCCTGGAGCGCGG
ATACGAAAGGGTCAGTCTCAACGATTTGATCGCGACCTCGGGGATGTCGAAAGGTGCTTTTTACCATTACTTTTCATCAA
AAGAGGCCCTGGTGTCCGCGCTGGCCGCACGCAGCGCAGACCAGGCATTCGAGGCCTTGCGGCCGGTCTTCGAGGCGCAG
GGCAGGGGCGCGCTGGAGCGTCTGAATTCCGGTCTGCGTGCCGGCTACGAGGTCAAAATGGCGCTCGGAGCGCCCGAGAG
TATCGGGGCGATGGCCTCGATGATGCGCCCGGAGAACCAGTCGCTGCTGCGCAGGATCTCGGCGATCTGGGAGGACAGGT
TCCGGCCGGTACTCACCGAGGTCATCGCGCAGGGAGTCGCCGAAGGGGTGTTCGACACATTCGATCCCGAGGGGGTCGGC
GACATGATCCAGGGCCTGGCGGCCACCATGGGCACCGCCGTGCAGCGCATCATCGCCGCCCCGGATGCGCCGGCGCGGGC
GCAGGCGATCGACGCTGCCGTGCTGCGTCAGCGTCTTTACGGTATTGCCACCGACCGGATACTCGGACTGCCCGACGGCA
CGGTCGAGGTGCTGGACCGCGACCAAATCGAGGCGCTGGTTGCCATGCTCTAG

Upstream 100 bases:

>100_bases
CTCGGTGCCCGCGGTGGGGCCGGTGCGTGGCTTCTTCCTGTTCATGGCCGTGGTCGGTGTGTATCTGACCTACGTCGGCT
GGATCAGGAAACGCTGACCC

Downstream 100 bases:

>100_bases
GCCGGCCCTGGCCGGGCGAGACGACATTCAGGTTCGCTAGTTCGCCCGCGATGTGTCCGCCAATGTCAGCTCGGCGCGGT
AACGGGCAATGTCGGACCCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPRVVKHPELRRTELLDLAMTLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSALAARSADQAFEALRPVFEAQ
GRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQSLLRRISAIWEDRFRPVLTEVIAQGVAEGVFDTFDPEGVG
DMIQGLAATMGTAVQRIIAAPDAPARAQAIDAAVLRQRLYGIATDRILGLPDGTVEVLDRDQIEALVAML

Sequences:

>Translated_230_residues
MPRVVKHPELRRTELLDLAMTLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSALAARSADQAFEALRPVFEAQ
GRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQSLLRRISAIWEDRFRPVLTEVIAQGVAEGVFDTFDPEGVG
DMIQGLAATMGTAVQRIIAAPDAPARAQAIDAAVLRQRLYGIATDRILGLPDGTVEVLDRDQIEALVAML
>Mature_229_residues
PRVVKHPELRRTELLDLAMTLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSALAARSADQAFEALRPVFEAQG
RGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQSLLRRISAIWEDRFRPVLTEVIAQGVAEGVFDTFDPEGVGD
MIQGLAATMGTAVQRIIAAPDAPARAQAIDAAVLRQRLYGIATDRILGLPDGTVEVLDRDQIEALVAML

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25019; Mature: 24888

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVVKHPELRRTELLDLAMTLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHH
LAARSADQAFEALRPVFEAQGRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHH
SLLRRISAIWEDRFRPVLTEVIAQGVAEGVFDTFDPEGVGDMIQGLAATMGTAVQRIIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
PDAPARAQAIDAAVLRQRLYGIATDRILGLPDGTVEVLDRDQIEALVAML
CCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PRVVKHPELRRTELLDLAMTLFLERGYERVSLNDLIATSGMSKGAFYHYFSSKEALVSA
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHH
LAARSADQAFEALRPVFEAQGRGALERLNSGLRAGYEVKMALGAPESIGAMASMMRPENQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCHH
SLLRRISAIWEDRFRPVLTEVIAQGVAEGVFDTFDPEGVGDMIQGLAATMGTAVQRIIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHC
PDAPARAQAIDAAVLRQRLYGIATDRILGLPDGTVEVLDRDQIEALVAML
CCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]