BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

Click here to switch to the map view.

The map label for this gene is yusZ [H]

Identifier: 169630587

GI number: 169630587

Start: 3548422

End: 3549198

Strand: Reverse

Name: yusZ [H]

Synonym: MAB_3506c

Alternate gene names: 169630587

Gene position: 3549198-3548422 (Counterclockwise)

Preceding gene: 169630589

Following gene: 169630586

Centisome position: 70.04

GC content: 60.75

Gene sequence:

>777_bases
ATGTCGAAGAAGATCCTGATCACCGGTGCAAGTTCTGGGTTTGGCCGAGGGGCTGCCATCGAACTCGCACGCCGTGGGCA
CCAGGTGGTTGCCACCGCGGAGACCTGGCCACAGGTACGCACCCTGCGCGCTGATGCCGCTGAGGCGGGTGTCGACCTGG
AGGTCATCAAGCTCAACCTGCTCGATGAGATCGACATCGCGCACGCCGCCGGCTACGACCCTGACGTACTGGTGCTCAAC
GCAGGGGTGATGGAAAGCGGTTCGATCATCGATATCCCACTGGCGCGTGTTCGGGAATCGTTCGATATCAACGTCTTTGG
ACACATTCAGCTGGCACAGGGCATTGTTCCGAAAATGGTCGCACGCAAATCAGGCAAAGTGGTGTGGACGTCTTCCATGG
GCGGAATCCTGGTCATTCCGTTCGTCGGGGTGTACTGCGCCACCAAACACGCCATCGAAGCGATCGCGGGTTCGATGAAG
GCCGAGCTGGAACCGCATGGCGTCAAGGTCGCCACCGTGAATCCCGGTTTGTTCGGTACCGGCTTCAACGACACGGGTGC
CGAGAGCCACGTGCAGTGGTACGACCCCGAACGTGCCGTGGTGCCCATGCCTTCGTTCGGAGACACGCTCGCCGATCAGT
TCGATCCGCAGGAAATGATCGATGCGATGGTCGAGATCATCCCCGCCGACGAGCACCTCTACCGCACCATGCGCCCGCTG
GCCACGATCGACGTCGCTAAGGGCTGGCAGGAAACTGAGTGGACGCAAAATGCCTGA

Upstream 100 bases:

>100_bases
ATAGCGCCGCATGTAACTAACTGTTTATTGACAATACTGGCCCCAGTAGGCAAGCTCGGTGTCGTCAAGGGGCACTTCTG
ATACCTCTGAAGGGAAATGC

Downstream 100 bases:

>100_bases
TATCACCTTGGAGCACGCGAACCAGCTGGTGGCCCGCGGCCTCGCGGCCGCGGAGAAGGCCGGAATGAAAGCGGTTTTCG
CGATCCTGGACAGCGGCGCC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSKKILITGASSGFGRGAAIELARRGHQVVATAETWPQVRTLRADAAEAGVDLEVIKLNLLDEIDIAHAAGYDPDVLVLN
AGVMESGSIIDIPLARVRESFDINVFGHIQLAQGIVPKMVARKSGKVVWTSSMGGILVIPFVGVYCATKHAIEAIAGSMK
AELEPHGVKVATVNPGLFGTGFNDTGAESHVQWYDPERAVVPMPSFGDTLADQFDPQEMIDAMVEIIPADEHLYRTMRPL
ATIDVAKGWQETEWTQNA

Sequences:

>Translated_258_residues
MSKKILITGASSGFGRGAAIELARRGHQVVATAETWPQVRTLRADAAEAGVDLEVIKLNLLDEIDIAHAAGYDPDVLVLN
AGVMESGSIIDIPLARVRESFDINVFGHIQLAQGIVPKMVARKSGKVVWTSSMGGILVIPFVGVYCATKHAIEAIAGSMK
AELEPHGVKVATVNPGLFGTGFNDTGAESHVQWYDPERAVVPMPSFGDTLADQFDPQEMIDAMVEIIPADEHLYRTMRPL
ATIDVAKGWQETEWTQNA
>Mature_257_residues
SKKILITGASSGFGRGAAIELARRGHQVVATAETWPQVRTLRADAAEAGVDLEVIKLNLLDEIDIAHAAGYDPDVLVLNA
GVMESGSIIDIPLARVRESFDINVFGHIQLAQGIVPKMVARKSGKVVWTSSMGGILVIPFVGVYCATKHAIEAIAGSMKA
ELEPHGVKVATVNPGLFGTGFNDTGAESHVQWYDPERAVVPMPSFGDTLADQFDPQEMIDAMVEIIPADEHLYRTMRPLA
TIDVAKGWQETEWTQNA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=34.2245989304813, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718074, Length=189, Percent_Identity=34.3915343915344, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI7706318, Length=185, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=29.6875, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40548397, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI214010158, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI214010156, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI22758144, Length=191, Percent_Identity=31.413612565445, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI150247226, Length=195, Percent_Identity=32.8205128205128, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI119392083, Length=193, Percent_Identity=30.0518134715026, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI157739938, Length=186, Percent_Identity=30.6451612903226, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI19743808, Length=191, Percent_Identity=30.3664921465969, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI44680136, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI44680133, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI17738292, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI7705925, Length=212, Percent_Identity=27.3584905660377, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=33.1550802139037, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40807363, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI142976729, Length=205, Percent_Identity=25.8536585365854, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=26.063829787234, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=30.5263157894737, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=30.5263157894737, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=32.6315789473684, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=245, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790717, Length=230, Percent_Identity=26.5217391304348, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788459, Length=220, Percent_Identity=28.1818181818182, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=185, Percent_Identity=31.8918918918919, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71997402, Length=185, Percent_Identity=30.2702702702703, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=197, Percent_Identity=28.9340101522843, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508895, Length=204, Percent_Identity=30.3921568627451, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=200, Percent_Identity=27, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559552, Length=191, Percent_Identity=27.2251308900524, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=30.1587301587302, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=208, Percent_Identity=28.3653846153846, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560176, Length=191, Percent_Identity=30.3664921465969, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=252, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17557668, Length=191, Percent_Identity=26.7015706806283, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=183, Percent_Identity=25.6830601092896, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=24.4725738396624, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=238, Percent_Identity=24.3697478991597, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=178, Percent_Identity=32.5842696629214, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=28.1407035175879, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=30.3664921465969, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=33.1578947368421, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571526, Length=204, Percent_Identity=30.8823529411765, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357041, Length=203, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648944, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=28.9772727272727, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=25.7028112449799, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=185, Percent_Identity=30.2702702702703, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640442, Length=189, Percent_Identity=24.8677248677249, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27801; Mature: 27670

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKILITGASSGFGRGAAIELARRGHQVVATAETWPQVRTLRADAAEAGVDLEVIKLNL
CCCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCHHHHHHCCHHHCCCCEEEEEEEC
LDEIDIAHAAGYDPDVLVLNAGVMESGSIIDIPLARVRESFDINVFGHIQLAQGIVPKMV
CCHHHHHHHCCCCCCEEEEECCCCCCCCEEECCHHHHHCCCCEEEEEEEEHHHCHHHHHH
ARKSGKVVWTSSMGGILVIPFVGVYCATKHAIEAIAGSMKAELEPHGVKVATVNPGLFGT
HHCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEC
GFNDTGAESHVQWYDPERAVVPMPSFGDTLADQFDPQEMIDAMVEIIPADEHLYRTMRPL
CCCCCCCCCCEEEECCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
ATIDVAKGWQETEWTQNA
HEEHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKKILITGASSGFGRGAAIELARRGHQVVATAETWPQVRTLRADAAEAGVDLEVIKLNL
CCEEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCHHHHHHCCHHHCCCCEEEEEEEC
LDEIDIAHAAGYDPDVLVLNAGVMESGSIIDIPLARVRESFDINVFGHIQLAQGIVPKMV
CCHHHHHHHCCCCCCEEEEECCCCCCCCEEECCHHHHHCCCCEEEEEEEEHHHCHHHHHH
ARKSGKVVWTSSMGGILVIPFVGVYCATKHAIEAIAGSMKAELEPHGVKVATVNPGLFGT
HHCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEC
GFNDTGAESHVQWYDPERAVVPMPSFGDTLADQFDPQEMIDAMVEIIPADEHLYRTMRPL
CCCCCCCCCCEEEECCCCCEEECCCCCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
ATIDVAKGWQETEWTQNA
HEEHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]