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The map label for this gene is hcaR [H]

Identifier: 169630490

GI number: 169630490

Start: 3456478

End: 3457191

Strand: Reverse

Name: hcaR [H]

Synonym: MAB_3409c

Alternate gene names: 169630490

Gene position: 3457191-3456478 (Counterclockwise)

Preceding gene: 169630494

Following gene: 169630489

Centisome position: 68.23

GC content: 68.77

Gene sequence:

>714_bases
GTGACCTCGCCCTCACTCACCCTCGGGTACGTCCCCGGTGGGACGCCCGCGAAGTGGGCACGGATCTGGACGCAACGTCA
TCCCGATGTCTCCCTGCAATTGCGCGCCGTCACCGCCGCCGAAGCGGCCGATGTGGTGCGGGACGGCGCCGTCGACATCG
CGTTGCTCCGGCCGCCGGCCGAGACCTCGGGGCTGGCGCTTATTCCTCTCTACGAAGAAACGACGGTGGCCGTGATACCC
ACCGATCACCTTCTCAGCGCCGTCGACGTGATCACCGCCGCAGATCTCGATGGCGAGCCGACGCTGCTGCCGCTCGATGA
CGTCCTGGCGTGGGCGGACGCCCCCGGCATCCCCGTCGGTCACCGGCCTGAGACCACCGCGGACGCAATAGAACTTGTTG
CCGCCGGGCTCGGCGCACTCATCGTTCCGCAGTCGCTGGCACGGCTGCATCACCGCAAGGACCTCACGTACCGGCCTATC
GCCGACGCACCTACGTGCCCGGTAGCACTGGCCTTTCCGGACGGCCAGCAGCCGCCACTTGTCGAGGAGTTCATCGGGAT
TGTGCGGGGTCGCAAACCGGATTCATCGCGAGGAAAGGCCGGGTCGGCCCCGAAGCGCACCGCGCGGGAGAAGACCCTCG
CAAAACAGGCTGCTCGCGCTGCGGCGGGCAAGGTCGCCCGCGACCCAGGCCGACCGAAGCGTGGTCGGCGCTGA

Upstream 100 bases:

>100_bases
CGCTTGTAGGTACACATCCAGCTTCTTCGCCGCCGTGGCGGGTTTCATGGACTGCGCGTTCGGCCTGCTCATGGCATCAG
CCTATCGGTAGCCTGAGGCA

Downstream 100 bases:

>100_bases
GCCTGAAAATCGTCGCGAGATTCAGGCTCGTCAGTGATCTAATGACCGCGTGACCCCCGACGAATGGTTGGAAGCACTGC
GCAAGGGGATCGCGGCCGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTSPSLTLGYVPGGTPAKWARIWTQRHPDVSLQLRAVTAAEAADVVRDGAVDIALLRPPAETSGLALIPLYEETTVAVIP
TDHLLSAVDVITAADLDGEPTLLPLDDVLAWADAPGIPVGHRPETTADAIELVAAGLGALIVPQSLARLHHRKDLTYRPI
ADAPTCPVALAFPDGQQPPLVEEFIGIVRGRKPDSSRGKAGSAPKRTAREKTLAKQAARAAAGKVARDPGRPKRGRR

Sequences:

>Translated_237_residues
MTSPSLTLGYVPGGTPAKWARIWTQRHPDVSLQLRAVTAAEAADVVRDGAVDIALLRPPAETSGLALIPLYEETTVAVIP
TDHLLSAVDVITAADLDGEPTLLPLDDVLAWADAPGIPVGHRPETTADAIELVAAGLGALIVPQSLARLHHRKDLTYRPI
ADAPTCPVALAFPDGQQPPLVEEFIGIVRGRKPDSSRGKAGSAPKRTAREKTLAKQAARAAAGKVARDPGRPKRGRR
>Mature_236_residues
TSPSLTLGYVPGGTPAKWARIWTQRHPDVSLQLRAVTAAEAADVVRDGAVDIALLRPPAETSGLALIPLYEETTVAVIPT
DHLLSAVDVITAADLDGEPTLLPLDDVLAWADAPGIPVGHRPETTADAIELVAAGLGALIVPQSLARLHHRKDLTYRPIA
DAPTCPVALAFPDGQQPPLVEEFIGIVRGRKPDSSRGKAGSAPKRTAREKTLAKQAARAAAGKVARDPGRPKRGRR

Specific function: Transcriptional activator of the hca operon for 3- phenylpropionic acid catabolism [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=202, Percent_Identity=27.2277227722772, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 24994; Mature: 24863

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSLTLGYVPGGTPAKWARIWTQRHPDVSLQLRAVTAAEAADVVRDGAVDIALLRPPA
CCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCEEEEEECCCC
ETSGLALIPLYEETTVAVIPTDHLLSAVDVITAADLDGEPTLLPLDDVLAWADAPGIPVG
CCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHCCCCCCCCC
HRPETTADAIELVAAGLGALIVPQSLARLHHRKDLTYRPIADAPTCPVALAFPDGQQPPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCH
VEEFIGIVRGRKPDSSRGKAGSAPKRTAREKTLAKQAARAAAGKVARDPGRPKRGRR
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TSPSLTLGYVPGGTPAKWARIWTQRHPDVSLQLRAVTAAEAADVVRDGAVDIALLRPPA
CCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHCCCEEEEEECCCC
ETSGLALIPLYEETTVAVIPTDHLLSAVDVITAADLDGEPTLLPLDDVLAWADAPGIPVG
CCCCEEEEEEECCCEEEEECHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHCCCCCCCCC
HRPETTADAIELVAAGLGALIVPQSLARLHHRKDLTYRPIADAPTCPVALAFPDGQQPPL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCH
VEEFIGIVRGRKPDSSRGKAGSAPKRTAREKTLAKQAARAAAGKVARDPGRPKRGRR
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 9603882 [H]