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The map label for this gene is ydiS [C]

Identifier: 169630487

GI number: 169630487

Start: 3453836

End: 3455035

Strand: Direct

Name: ydiS [C]

Synonym: MAB_3406

Alternate gene names: 169630487

Gene position: 3453836-3455035 (Clockwise)

Preceding gene: 169630486

Following gene: 169630488

Centisome position: 68.16

GC content: 65.83

Gene sequence:

>1200_bases
GTGAGCGAGAAGCACTACGACATTGCGGTAGTCGGCGGGGGCCCGGCCGGGTCATCTGCGGCCTGGCAGGCCGCCCGCAC
GGGTGCCCGCGTGGTGCTCGTCGACAAGGCCGAGTTCCCGCGGGATAAGCCCTGCGGTGATGGGCTGACCGCCCGCGCGG
TGAGCTACCTGCAGAAGATGGGTCTGGCCCAGGAGGTTGCCCAATTCCACCGGGTCGACGGGGTGCGGGTCGACAGCGGG
AGCATCTGGGAACTGACCTTCCCGAAGCGTCCGGGCATGCCCGATCACGGGCATGTGGTGCGGCGGCCCGAGCTGGACAC
CCTGCTGCTCAAGCACGCCGAATCCGCCGGTGTCGAGGTGCGCCAGTCCACCGAAGCGGTGGGACCGGTGGGCGATGGGG
ATCTGGTCAAGGGTGTCGAGGTCAAGACGGCCAACGGATCCCGCGAAACCATCTCGGCGGACGCGGTGATCGTCGCGGAT
GGCGCCTACTCCCCCTTCAAACGCGCGATGAACATCGACTCTGAATACAAGGGATACAGCGCGATCGCGATCCGCGCCGA
GATGACGGCCAACCGCGAAGATTCCAACATGCTGGACATCGACCTGCGGATCCACCACAAGCAGGACGCACTGCCCGGAT
ACGGCTGGGTGTTCCCACTGGGCGGCGGACGCATCAACATCGGCATCGGATACGTCAACAGCTACCGGAGGTGGCAGGAC
GTCAACGCCGCGCAGGTGCTGGACACCTACATGAACAAGCTGCCCAAAGAATGGGAGCTGCCCAATCTTGCCGAACTGCG
CAAGAACAAGGGCGTGCGCGCATGGCGCTTGCCCATGGGATTCACCGCCTGGCCGCCGTGGCGGCCGGGCGTGCTCTTCG
CGGGCGACTCGCTGGGCGCGGGCAAGCCCGCCAGTGGCGCCGGTATCTCCAAGGCACTCGAATCCGGTTTGGCCGCAGGC
GAATGCGCGGTGGCCGCGTTGCAGAACGCCGGACCGCAGGACTTCATCAATTATGAGCAGCGGATGAATGAGGCCTGGGG
CAAGGAGTACAAACGCGGCCGGCTGATGCACCGCGCCATCGGCAACCCGTGGCTGTGCGCGCAGGGCATCAAGCTCATCG
ACAACGACCTGTTCCGTGACCGGATGCTCAAGGTGCTGTACAAGCGAGCACAGGGCCCCGGACACAAGACGTCGCACTAG

Upstream 100 bases:

>100_bases
CCAGCGCACGCACCGCATACGAGAACCGTGCCGGTTCGAGCCTGGGTGTGACCAAACCCGACGGCGAATAGACGCGCTCG
CGGCCCTTACTATTTGTTAT

Downstream 100 bases:

>100_bases
TACCGCCGTGTGGTCCATCCGGCGGCGGGAGATGGTGCTTGCCACCGGACTATCCACTGTCGCAGGGTTTCTCGACGCGA
TCGGATTTGTGCACCTGGGC

Product: geranylgeranyl reductase

Products: NA

Alternate protein names: DGGGPL reductase; 2,3-di-O-geranylgeranylglyceryl phosphate reductase; Geranylgeranyl reductase; GGR [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSEKHYDIAVVGGGPAGSSAAWQAARTGARVVLVDKAEFPRDKPCGDGLTARAVSYLQKMGLAQEVAQFHRVDGVRVDSG
SIWELTFPKRPGMPDHGHVVRRPELDTLLLKHAESAGVEVRQSTEAVGPVGDGDLVKGVEVKTANGSRETISADAVIVAD
GAYSPFKRAMNIDSEYKGYSAIAIRAEMTANREDSNMLDIDLRIHHKQDALPGYGWVFPLGGGRINIGIGYVNSYRRWQD
VNAAQVLDTYMNKLPKEWELPNLAELRKNKGVRAWRLPMGFTAWPPWRPGVLFAGDSLGAGKPASGAGISKALESGLAAG
ECAVAALQNAGPQDFINYEQRMNEAWGKEYKRGRLMHRAIGNPWLCAQGIKLIDNDLFRDRMLKVLYKRAQGPGHKTSH

Sequences:

>Translated_399_residues
MSEKHYDIAVVGGGPAGSSAAWQAARTGARVVLVDKAEFPRDKPCGDGLTARAVSYLQKMGLAQEVAQFHRVDGVRVDSG
SIWELTFPKRPGMPDHGHVVRRPELDTLLLKHAESAGVEVRQSTEAVGPVGDGDLVKGVEVKTANGSRETISADAVIVAD
GAYSPFKRAMNIDSEYKGYSAIAIRAEMTANREDSNMLDIDLRIHHKQDALPGYGWVFPLGGGRINIGIGYVNSYRRWQD
VNAAQVLDTYMNKLPKEWELPNLAELRKNKGVRAWRLPMGFTAWPPWRPGVLFAGDSLGAGKPASGAGISKALESGLAAG
ECAVAALQNAGPQDFINYEQRMNEAWGKEYKRGRLMHRAIGNPWLCAQGIKLIDNDLFRDRMLKVLYKRAQGPGHKTSH
>Mature_398_residues
SEKHYDIAVVGGGPAGSSAAWQAARTGARVVLVDKAEFPRDKPCGDGLTARAVSYLQKMGLAQEVAQFHRVDGVRVDSGS
IWELTFPKRPGMPDHGHVVRRPELDTLLLKHAESAGVEVRQSTEAVGPVGDGDLVKGVEVKTANGSRETISADAVIVADG
AYSPFKRAMNIDSEYKGYSAIAIRAEMTANREDSNMLDIDLRIHHKQDALPGYGWVFPLGGGRINIGIGYVNSYRRWQDV
NAAQVLDTYMNKLPKEWELPNLAELRKNKGVRAWRLPMGFTAWPPWRPGVLFAGDSLGAGKPASGAGISKALESGLAAGE
CAVAALQNAGPQDFINYEQRMNEAWGKEYKRGRLMHRAIGNPWLCAQGIKLIDNDLFRDRMLKVLYKRAQGPGHKTSH

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR016040
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.5.5.- [C]

Molecular weight: Translated: 43595; Mature: 43464

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS01098 LIPASE_GDSL_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKHYDIAVVGGGPAGSSAAWQAARTGARVVLVDKAEFPRDKPCGDGLTARAVSYLQKM
CCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHC
GLAQEVAQFHRVDGVRVDSGSIWELTFPKRPGMPDHGHVVRRPELDTLLLKHAESAGVEV
CHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCEE
RQSTEAVGPVGDGDLVKGVEVKTANGSRETISADAVIVADGAYSPFKRAMNIDSEYKGYS
HHCCCCCCCCCCCCCCCCEEEEECCCCCCEEECCEEEEECCCCHHHHHHHCCCCCCCCEE
AIAIRAEMTANREDSNMLDIDLRIHHKQDALPGYGWVFPLGGGRINIGIGYVNSYRRWQD
EEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCCEEEEEEEECHHHHHHHC
VNAAQVLDTYMNKLPKEWELPNLAELRKNKGVRAWRLPMGFTAWPPWRPGVLFAGDSLGA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCC
GKPASGAGISKALESGLAAGECAVAALQNAGPQDFINYEQRMNEAWGKEYKRGRLMHRAI
CCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNPWLCAQGIKLIDNDLFRDRMLKVLYKRAQGPGHKTSH
CCCEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SEKHYDIAVVGGGPAGSSAAWQAARTGARVVLVDKAEFPRDKPCGDGLTARAVSYLQKM
CCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHC
GLAQEVAQFHRVDGVRVDSGSIWELTFPKRPGMPDHGHVVRRPELDTLLLKHAESAGVEV
CHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCEE
RQSTEAVGPVGDGDLVKGVEVKTANGSRETISADAVIVADGAYSPFKRAMNIDSEYKGYS
HHCCCCCCCCCCCCCCCCEEEEECCCCCCEEECCEEEEECCCCHHHHHHHCCCCCCCCEE
AIAIRAEMTANREDSNMLDIDLRIHHKQDALPGYGWVFPLGGGRINIGIGYVNSYRRWQD
EEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCCEEEEEEEECHHHHHHHC
VNAAQVLDTYMNKLPKEWELPNLAELRKNKGVRAWRLPMGFTAWPPWRPGVLFAGDSLGA
CCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCCC
GKPASGAGISKALESGLAAGECAVAALQNAGPQDFINYEQRMNEAWGKEYKRGRLMHRAI
CCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNPWLCAQGIKLIDNDLFRDRMLKVLYKRAQGPGHKTSH
CCCEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]