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The map label for this gene is pbuG [H]

Identifier: 169630434

GI number: 169630434

Start: 3400657

End: 3402102

Strand: Reverse

Name: pbuG [H]

Synonym: MAB_3353c

Alternate gene names: 169630434

Gene position: 3402102-3400657 (Counterclockwise)

Preceding gene: 169630437

Following gene: 169630433

Centisome position: 67.14

GC content: 63.69

Gene sequence:

>1446_bases
ATGACTGCGCTCCTGGACCGGTTCTTCCGGATAACTGAACGGCAGTCGACTCTCGGGCGAGAGATTCGTGGCGGGGTCGT
CACCTTCTTCGCGATGGCCTACATCGTGGTACTCAACCCGCTCATCATCGGTGGCGAGCCGGGACGCGCGCACAACGTGG
ATGTGCTGGGCCACGTGCTCCCGGTGGGACAGGTAGCGGCGGTCACGGCCCTGGCTGCCGGTGTCATGTCGATCCTGTTC
GGATTCGTCGCCAACTACCCGTTCGCGCTTGCCGCCGGACTGGGCATCAACAGTCTGCTGGCAGTGTCATTCGCTCCCCA
GATGACGTGGCCCGAGGCGATGGGGTTGGTGATTGTCGACGGCCTGATCATTGTGGCGCTTGGCATTTCAGGATTTCGTA
CTGCGGTTTTCCATGCGATTCCCGACGAGCTGAAAGCGGCGATCGCCGCGGGTATCGGATGCTTCATCGCATTCATCGGC
TTTGTCGACGCCGGCTTTGTGCGTCGCGTCCCCGATGCCGCAAACACCACCGTGCCGGTAGGGCTGGGTATCGACAACTC
GGTGGCCACCATCCCGACGCTGATTTTTGCCGCGGGTGTGCTGCTGATGGGAATCCTGGTGGTGCGCAAGGTCCGTGGCG
GATTGCTCATCGGCATCGTGGCGATGACTGTCGTATCGATGATCGCGCAGGCGTTGTGCGGCCGGGGTGCGCAACCCACC
GATGCCAAGGGCTGGAATCTCACCGTGCCCGATTGGCCGTCATCGGCGGGCGGCATGCCGGATCTGAGTCTGCTGGGCCA
GGTCGACCTTTTCGGTGCCTTTACGCGGGTGGGCGTGCTGTCGGCGACGGTGCTGGTGTTCGCGTTGGTGCTCTCCAACT
TCTTCGATGCCATGGGCACCATGACGGGCCTGGGCAAGGAGGCCGGCCTGGCCGACGAGCACGGCACGTTGCCGGGCATC
GGGCGGGCGCTCACTGTGGAGGGTGTCGGAGCGGTGATCGGTGGTGTCTCCTCCTCGTCCTCCAACACCGTATATGTCGA
GTCGGCCTCCGGAATCGCGGAGGGCGCACGCACCGGGCTGGCCAACGTTGTTACCGGGCTGCTGTTCCTGGCGGCCATGT
TCTTCACACCGCTGTATTCGGTGGTGCCGCTGGAGGCGGCGGCGCCGGCTCTGGTGGTGGTCGGCGCGATGATGATCGGG
CAGTTGCGCAGCGTGGACCTAACCCGGTTCGACTACGCGTTGCCCTGCTTTCTCACAGTGGTGACGATGCCGTTCACCTA
CTCGATTGCCAACGGGATCGGCGTCGGGTTCATCAGCTGGGTGGTTCTGGCGCTCGCACGTGGCAGATTTCGGTCGGTGC
ATCCGCTGCTGTATGTGGTGGCGATGTTGTTCGTCATCTACTTCGCCAAGGGGCCGATCGAGGATCTCCTGGCCCATGGC
GCCTAA

Upstream 100 bases:

>100_bases
GCCTCTAGTGACGAAGGTCCCTCACTGCGGGTGGGAAAGTCCCCTCTCGCCGAATGCACCGGTGGGCGTTTGTTAGCCGT
GGCCTGTACGTTCAACGGCT

Downstream 100 bases:

>100_bases
CGTCTTGTCTGTGAGTATGTGGGCGAAGGGAACTGGTCTGGGTTCGTGGCCTGGTCAACAGGCGCGTGACGCGACCGAGA
TCGTGGTGGCCGAGCTGCCG

Product: putative xanthine/uracil/vitamin C permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTALLDRFFRITERQSTLGREIRGGVVTFFAMAYIVVLNPLIIGGEPGRAHNVDVLGHVLPVGQVAAVTALAAGVMSILF
GFVANYPFALAAGLGINSLLAVSFAPQMTWPEAMGLVIVDGLIIVALGISGFRTAVFHAIPDELKAAIAAGIGCFIAFIG
FVDAGFVRRVPDAANTTVPVGLGIDNSVATIPTLIFAAGVLLMGILVVRKVRGGLLIGIVAMTVVSMIAQALCGRGAQPT
DAKGWNLTVPDWPSSAGGMPDLSLLGQVDLFGAFTRVGVLSATVLVFALVLSNFFDAMGTMTGLGKEAGLADEHGTLPGI
GRALTVEGVGAVIGGVSSSSSNTVYVESASGIAEGARTGLANVVTGLLFLAAMFFTPLYSVVPLEAAAPALVVVGAMMIG
QLRSVDLTRFDYALPCFLTVVTMPFTYSIANGIGVGFISWVVLALARGRFRSVHPLLYVVAMLFVIYFAKGPIEDLLAHG
A

Sequences:

>Translated_481_residues
MTALLDRFFRITERQSTLGREIRGGVVTFFAMAYIVVLNPLIIGGEPGRAHNVDVLGHVLPVGQVAAVTALAAGVMSILF
GFVANYPFALAAGLGINSLLAVSFAPQMTWPEAMGLVIVDGLIIVALGISGFRTAVFHAIPDELKAAIAAGIGCFIAFIG
FVDAGFVRRVPDAANTTVPVGLGIDNSVATIPTLIFAAGVLLMGILVVRKVRGGLLIGIVAMTVVSMIAQALCGRGAQPT
DAKGWNLTVPDWPSSAGGMPDLSLLGQVDLFGAFTRVGVLSATVLVFALVLSNFFDAMGTMTGLGKEAGLADEHGTLPGI
GRALTVEGVGAVIGGVSSSSSNTVYVESASGIAEGARTGLANVVTGLLFLAAMFFTPLYSVVPLEAAAPALVVVGAMMIG
QLRSVDLTRFDYALPCFLTVVTMPFTYSIANGIGVGFISWVVLALARGRFRSVHPLLYVVAMLFVIYFAKGPIEDLLAHG
A
>Mature_480_residues
TALLDRFFRITERQSTLGREIRGGVVTFFAMAYIVVLNPLIIGGEPGRAHNVDVLGHVLPVGQVAAVTALAAGVMSILFG
FVANYPFALAAGLGINSLLAVSFAPQMTWPEAMGLVIVDGLIIVALGISGFRTAVFHAIPDELKAAIAAGIGCFIAFIGF
VDAGFVRRVPDAANTTVPVGLGIDNSVATIPTLIFAAGVLLMGILVVRKVRGGLLIGIVAMTVVSMIAQALCGRGAQPTD
AKGWNLTVPDWPSSAGGMPDLSLLGQVDLFGAFTRVGVLSATVLVFALVLSNFFDAMGTMTGLGKEAGLADEHGTLPGIG
RALTVEGVGAVIGGVSSSSSNTVYVESASGIAEGARTGLANVVTGLLFLAAMFFTPLYSVVPLEAAAPALVVVGAMMIGQ
LRSVDLTRFDYALPCFLTVVTMPFTYSIANGIGVGFISWVVLALARGRFRSVHPLLYVVAMLFVIYFAKGPIEDLLAHGA

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=463, Percent_Identity=34.1252699784017, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1790150, Length=466, Percent_Identity=34.549356223176, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1790499, Length=469, Percent_Identity=30.9168443496802, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI48994909, Length=444, Percent_Identity=31.7567567567568, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 49773; Mature: 49642

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00334 MYB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALLDRFFRITERQSTLGREIRGGVVTFFAMAYIVVLNPLIIGGEPGRAHNVDVLGHVL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHH
PVGQVAAVTALAAGVMSILFGFVANYPFALAAGLGINSLLAVSFAPQMTWPEAMGLVIVD
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHH
GLIIVALGISGFRTAVFHAIPDELKAAIAAGIGCFIAFIGFVDAGFVRRVPDAANTTVPV
HHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
GLGIDNSVATIPTLIFAAGVLLMGILVVRKVRGGLLIGIVAMTVVSMIAQALCGRGAQPT
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DAKGWNLTVPDWPSSAGGMPDLSLLGQVDLFGAFTRVGVLSATVLVFALVLSNFFDAMGT
CCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGLGKEAGLADEHGTLPGIGRALTVEGVGAVIGGVSSSSSNTVYVESASGIAEGARTGL
HHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHH
ANVVTGLLFLAAMFFTPLYSVVPLEAAAPALVVVGAMMIGQLRSVDLTRFDYALPCFLTV
HHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VTMPFTYSIANGIGVGFISWVVLALARGRFRSVHPLLYVVAMLFVIYFAKGPIEDLLAHG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCC
A
C
>Mature Secondary Structure 
TALLDRFFRITERQSTLGREIRGGVVTFFAMAYIVVLNPLIIGGEPGRAHNVDVLGHVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHH
PVGQVAAVTALAAGVMSILFGFVANYPFALAAGLGINSLLAVSFAPQMTWPEAMGLVIVD
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHH
GLIIVALGISGFRTAVFHAIPDELKAAIAAGIGCFIAFIGFVDAGFVRRVPDAANTTVPV
HHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
GLGIDNSVATIPTLIFAAGVLLMGILVVRKVRGGLLIGIVAMTVVSMIAQALCGRGAQPT
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
DAKGWNLTVPDWPSSAGGMPDLSLLGQVDLFGAFTRVGVLSATVLVFALVLSNFFDAMGT
CCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTGLGKEAGLADEHGTLPGIGRALTVEGVGAVIGGVSSSSSNTVYVESASGIAEGARTGL
HHCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHH
ANVVTGLLFLAAMFFTPLYSVVPLEAAAPALVVVGAMMIGQLRSVDLTRFDYALPCFLTV
HHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VTMPFTYSIANGIGVGFISWVVLALARGRFRSVHPLLYVVAMLFVIYFAKGPIEDLLAHG
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]