Click here to switch to the map view.

The map label for this gene is ilvC [H]

Identifier: 169630402

GI number: 169630402

Start: 3366525

End: 3367526

Strand: Reverse

Name: ilvC [H]

Synonym: MAB_3321c

Alternate gene names: 169630402

Gene position: 3367526-3366525 (Counterclockwise)

Preceding gene: 169630403

Following gene: 169630401

Centisome position: 66.46

GC content: 64.27

Gene sequence:

>1002_bases
ATGTTCTACGACGACGATGCGGACCTGACCCTCATTCAGGGACGTAAGGTCGGCGTTATCGGGTACGGCAGCCAGGGGCA
CGCGCACTCGCTGAGCCTGCGCGACTCCGGCGTTCAGGTGAAGGTCGGCCTGCGTGAGGGCTCCAAGTCGCGCGAGAAGG
TCACCGAGCAGGGGCTGGAGGTCGATACCCCCGAAGAGGTCGCCAAGTGGGCCGACGTCATCATGATCCTGGCGCCCGAC
ACCGCGCAGGCCGAGATCTTCAAGAACGAGATCGAGCCGCACCTCAAGGACGGCGATGCGCTGTTCTTCGGACACGGTCT
GAACATCCACTTCGGGCTGATCAAGCCTCCGGCCAACGTCACCGTTGCCATGGTCGCCCCGAAGGGCCCCGGCCACCTGG
TGCGTCGCCAGTTCGTCGACGGCAAGGGTGTGCCCGCACTGATCGCCGTGCACCAGGACCCCAAGGGTGAGGGCCAGGCC
CTCGCGCTGTCGTACGCCAAGGGCATCGGTGGCACCCGCGCCGGCGTCATCAAGACCGATTTCAAGGAAGAGACCGAGAC
CGATCTGTTCGGTGAGCAGGCCGTGCTCTGCGGTGGCACCGAGGAACTGGTCAAGACCGGATTCGACGTCATGGTGGAGG
CCGGCTACGCCCCCGAGATGGCGTACTTCGAGGTGCTGCACGAACTCAAGCTGATCGTCGACCTGATGTACGAGGGTGGC
ATCGCCCGCATGAACTACTCGGTGTCCGACACCGCTGAGTTCGGTGGATATTTGAGCGGTCCCCGTGTTATCGATGCCGG
GACCAAGGACCGGATGCGCCAGATCCTCAAGGAGATCCAGGACGGCACCTTCGTCAAGCGCCTCGTCGCCAACGTCGAGG
GTGGCAACAAGGAGCTCGAGGGTCTGCGCAAGGAGAACGCCGAGCACCCGATCGAGGTCACCGGCAAGAAGCTGCGCGAC
CTGATGAGCTGGGTCGACCGGCCCATCACCGAGACCGCTTAG

Upstream 100 bases:

>100_bases
GCTCTCGCGCGGCCCGCGGTCTATCGCCGCCGCCAAGTAGTACTTAAAAGAGAAGTACCGAAGAGAAAAGCCGAAGGGAA
TCAAGCAAGTGGCAGTTGAG

Downstream 100 bases:

>100_bases
TCTCTGTTGATCTGAACGCAAGGCCCCCGCACTCTCCGGAGTGACGGGGGCTTTTGCGTTTCCGCGGTCTGTGCTCGACG
GGAATGGTGTCCGTCGAGTA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MFYDDDADLTLIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLREGSKSREKVTEQGLEVDTPEEVAKWADVIMILAPD
TAQAEIFKNEIEPHLKDGDALFFGHGLNIHFGLIKPPANVTVAMVAPKGPGHLVRRQFVDGKGVPALIAVHQDPKGEGQA
LALSYAKGIGGTRAGVIKTDFKEETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYAPEMAYFEVLHELKLIVDLMYEGG
IARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMRQILKEIQDGTFVKRLVANVEGGNKELEGLRKENAEHPIEVTGKKLRD
LMSWVDRPITETA

Sequences:

>Translated_333_residues
MFYDDDADLTLIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLREGSKSREKVTEQGLEVDTPEEVAKWADVIMILAPD
TAQAEIFKNEIEPHLKDGDALFFGHGLNIHFGLIKPPANVTVAMVAPKGPGHLVRRQFVDGKGVPALIAVHQDPKGEGQA
LALSYAKGIGGTRAGVIKTDFKEETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYAPEMAYFEVLHELKLIVDLMYEGG
IARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMRQILKEIQDGTFVKRLVANVEGGNKELEGLRKENAEHPIEVTGKKLRD
LMSWVDRPITETA
>Mature_333_residues
MFYDDDADLTLIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLREGSKSREKVTEQGLEVDTPEEVAKWADVIMILAPD
TAQAEIFKNEIEPHLKDGDALFFGHGLNIHFGLIKPPANVTVAMVAPKGPGHLVRRQFVDGKGVPALIAVHQDPKGEGQA
LALSYAKGIGGTRAGVIKTDFKEETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYAPEMAYFEVLHELKLIVDLMYEGG
IARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMRQILKEIQDGTFVKRLVANVEGGNKELEGLRKENAEHPIEVTGKKLRD
LMSWVDRPITETA

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=323, Percent_Identity=35.9133126934984, Blast_Score=165, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323387, Length=305, Percent_Identity=31.8032786885246, Blast_Score=117, Evalue=2e-27,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 36261; Mature: 36261

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYDDDADLTLIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLREGSKSREKVTEQGLE
CCCCCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHCCCC
VDTPEEVAKWADVIMILAPDTAQAEIFKNEIEPHLKDGDALFFGHGLNIHFGLIKPPANV
CCCHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCE
TVAMVAPKGPGHLVRRQFVDGKGVPALIAVHQDPKGEGQALALSYAKGIGGTRAGVIKTD
EEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCEEECC
FKEETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYAPEMAYFEVLHELKLIVDLMYEGG
CCHHHHHHHCCCCEEEECCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
IARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMRQILKEIQDGTFVKRLVANVEGGNKELE
EEEEECCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
GLRKENAEHPIEVTGKKLRDLMSWVDRPITETA
HHHHCCCCCCHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFYDDDADLTLIQGRKVGVIGYGSQGHAHSLSLRDSGVQVKVGLREGSKSREKVTEQGLE
CCCCCCCCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHCCCC
VDTPEEVAKWADVIMILAPDTAQAEIFKNEIEPHLKDGDALFFGHGLNIHFGLIKPPANV
CCCHHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEEECCCCCE
TVAMVAPKGPGHLVRRQFVDGKGVPALIAVHQDPKGEGQALALSYAKGIGGTRAGVIKTD
EEEEEECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEHHCCCCCCCCEEECC
FKEETETDLFGEQAVLCGGTEELVKTGFDVMVEAGYAPEMAYFEVLHELKLIVDLMYEGG
CCHHHHHHHCCCCEEEECCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCC
IARMNYSVSDTAEFGGYLSGPRVIDAGTKDRMRQILKEIQDGTFVKRLVANVEGGNKELE
EEEEECCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
GLRKENAEHPIEVTGKKLRDLMSWVDRPITETA
HHHHCCCCCCHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA