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The map label for this gene is ubiB [C]

Identifier: 169630395

GI number: 169630395

Start: 3351839

End: 3353254

Strand: Direct

Name: ubiB [C]

Synonym: MAB_3314

Alternate gene names: 169630395

Gene position: 3351839-3353254 (Clockwise)

Preceding gene: 169630393

Following gene: 169630396

Centisome position: 66.15

GC content: 60.88

Gene sequence:

>1416_bases
ATGGCGGAGGAGCCAGTACCCAGGGGACGGATCCGGCGCACCATGCCACTGGCAGGCTTCACCGCCCGCGCAGCGGGCGG
ACGACTCGTCGCGGGCCTACGCGAAAAGGCCGGAGACACCGGAGCCGTCGACCGCTTCCATCACCGCACAGCCGAGCGCT
ACACCGAACTCCTCGGGCACTCCAAAGGCGTTCTGATGAAGGCAGGACAGATCTTTTCGAGCATCGATATGAACGGTGCC
GACGGCGGAATCTCGCCGTACGAGCAGGCATTGACTCGACTTCAAACCCAATCGCCGCCCATGGCCCCCGCATTGGCGCG
TAGTGTCCTCGAATCTGAGCTCCGCGTACCTACAAGCCAGGCGTACGCCAGTTTCACCGACGATCCGATCTCTGCGGCCT
CGATCGGCCAGGTTCACCGTGCGACGCTTCACGATGGCCGTGATGTCGTCGTGAAGATTCAATACCCCGGTGTGGCACAG
GCGATTCAAGATGACCTCGCCAACACCGAGCTGGTCACCACATTCTTGCGAGTCACCTTTGCGCTGTTGGACCGCAGATA
CGCGATCGATCTTCCTGCGACGGCACGAGATATCTCGGCTCAAATCAAGGAGGAACTGGACTATAAGCAGGAGGCGGAGA
ATATCTCCGCGTTCCACCGGCTGTTCGCCGGGCACCCGTTCATCCGGGTACCCCAGGCAGTACCGGAGCTGTCCACGCGC
CGAGTCCTCACGATGACCTATGTCGACGGGATCGACTGGACCGAAGCGCAACAAGCCGACCAAGAGCTGAAAAATACTTG
GGCGGAGGCACTGTGGAGATTCAGCCTTGCACCGCTGCAACATGCTTGCGCCTTCTACACAGATCTGCATCCCGGCAACT
ACCGGTTCGGACTGGACGGTAGCCTCGGAATTGTCGATTTCGGATCCGTCAAGAACCTTCGGGAGAGCCATCGTCTCGCC
TGGATTCGGATGGTCGCCGCAAGCATCCAACAGCGACCTGCCGATCTCCACTCCACGATGAAAGAAGCGGGCTTCCTTGC
CGCCCACTCCAGCATGTCCGCCGACGAAGCTCTCCGCTGGATGAATGAGATCAACGCTGACGCAACGCTGCCACAGCCGG
TCACCTACACACCGCAATTGATAGACCGCAACCTCACCGCGCTGGACAGCTCGCTATCGCGTCGCATCTCCCTACCCCCC
GAGCTCATCTACCTGGTGCGTTTCCCACTCGGCGTCCGGTCTGCAATGTCAAAACTCGGGGCCACCGTGAGCTCCCGATC
CGCTGCTGCCGACATGATCGGAATCGCGGAACCAGATACCGCCCTTGGCATTCGACATGTTGCCTGGGTGAAGGAACGCG
GCCTACCGTTCGGTCTGGACCCACGCGAGCAGTCAGAGGTTGGTGCCCGGTTATGA

Upstream 100 bases:

>100_bases
TTTCGTGGAAATCTCACCCATTGACGCCTCCAAAGTAATCACTTAGTCTCACTCAGTGAGTACTTTAACACCCGGGACGG
GTCATCGGTAGGAGGACGCC

Downstream 100 bases:

>100_bases
GTGACCGTCACATTCCCCGGGGACGGATCCGGCGCACCATGCCACTGGCAGGCTTCACCGCCCGTGCAGCAGGCGGCCGA
CTCGTCGCGGGCCTACGTGA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MAEEPVPRGRIRRTMPLAGFTARAAGGRLVAGLREKAGDTGAVDRFHHRTAERYTELLGHSKGVLMKAGQIFSSIDMNGA
DGGISPYEQALTRLQTQSPPMAPALARSVLESELRVPTSQAYASFTDDPISAASIGQVHRATLHDGRDVVVKIQYPGVAQ
AIQDDLANTELVTTFLRVTFALLDRRYAIDLPATARDISAQIKEELDYKQEAENISAFHRLFAGHPFIRVPQAVPELSTR
RVLTMTYVDGIDWTEAQQADQELKNTWAEALWRFSLAPLQHACAFYTDLHPGNYRFGLDGSLGIVDFGSVKNLRESHRLA
WIRMVAASIQQRPADLHSTMKEAGFLAAHSSMSADEALRWMNEINADATLPQPVTYTPQLIDRNLTALDSSLSRRISLPP
ELIYLVRFPLGVRSAMSKLGATVSSRSAAADMIGIAEPDTALGIRHVAWVKERGLPFGLDPREQSEVGARL

Sequences:

>Translated_471_residues
MAEEPVPRGRIRRTMPLAGFTARAAGGRLVAGLREKAGDTGAVDRFHHRTAERYTELLGHSKGVLMKAGQIFSSIDMNGA
DGGISPYEQALTRLQTQSPPMAPALARSVLESELRVPTSQAYASFTDDPISAASIGQVHRATLHDGRDVVVKIQYPGVAQ
AIQDDLANTELVTTFLRVTFALLDRRYAIDLPATARDISAQIKEELDYKQEAENISAFHRLFAGHPFIRVPQAVPELSTR
RVLTMTYVDGIDWTEAQQADQELKNTWAEALWRFSLAPLQHACAFYTDLHPGNYRFGLDGSLGIVDFGSVKNLRESHRLA
WIRMVAASIQQRPADLHSTMKEAGFLAAHSSMSADEALRWMNEINADATLPQPVTYTPQLIDRNLTALDSSLSRRISLPP
ELIYLVRFPLGVRSAMSKLGATVSSRSAAADMIGIAEPDTALGIRHVAWVKERGLPFGLDPREQSEVGARL
>Mature_470_residues
AEEPVPRGRIRRTMPLAGFTARAAGGRLVAGLREKAGDTGAVDRFHHRTAERYTELLGHSKGVLMKAGQIFSSIDMNGAD
GGISPYEQALTRLQTQSPPMAPALARSVLESELRVPTSQAYASFTDDPISAASIGQVHRATLHDGRDVVVKIQYPGVAQA
IQDDLANTELVTTFLRVTFALLDRRYAIDLPATARDISAQIKEELDYKQEAENISAFHRLFAGHPFIRVPQAVPELSTRR
VLTMTYVDGIDWTEAQQADQELKNTWAEALWRFSLAPLQHACAFYTDLHPGNYRFGLDGSLGIVDFGSVKNLRESHRLAW
IRMVAASIQQRPADLHSTMKEAGFLAAHSSMSADEALRWMNEINADATLPQPVTYTPQLIDRNLTALDSSLSRRISLPPE
LIYLVRFPLGVRSAMSKLGATVSSRSAAADMIGIAEPDTALGIRHVAWVKERGLPFGLDPREQSEVGARL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI27363457, Length=392, Percent_Identity=29.3367346938776, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI34147522, Length=373, Percent_Identity=26.8096514745308, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI217416386, Length=358, Percent_Identity=29.3296089385475, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI40254938, Length=295, Percent_Identity=26.7796610169492, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI217035081, Length=227, Percent_Identity=27.3127753303965, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI41393593, Length=216, Percent_Identity=28.7037037037037, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI2367309, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32565180, Length=387, Percent_Identity=26.3565891472868, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17559152, Length=313, Percent_Identity=27.4760383386581, Blast_Score=104, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6321319, Length=435, Percent_Identity=27.1264367816092, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI18859849, Length=366, Percent_Identity=29.2349726775956, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI22024280, Length=290, Percent_Identity=25.8620689655172, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24662575, Length=256, Percent_Identity=25.78125, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 51787; Mature: 51656

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEEPVPRGRIRRTMPLAGFTARAAGGRLVAGLREKAGDTGAVDRFHHRTAERYTELLGH
CCCCCCCCCHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
SKGVLMKAGQIFSSIDMNGADGGISPYEQALTRLQTQSPPMAPALARSVLESELRVPTSQ
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
AYASFTDDPISAASIGQVHRATLHDGRDVVVKIQYPGVAQAIQDDLANTELVTTFLRVTF
HHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHH
ALLDRRYAIDLPATARDISAQIKEELDYKQEAENISAFHRLFAGHPFIRVPQAVPELSTR
HHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCCCC
RVLTMTYVDGIDWTEAQQADQELKNTWAEALWRFSLAPLQHACAFYTDLHPGNYRFGLDG
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
SLGIVDFGSVKNLRESHRLAWIRMVAASIQQRPADLHSTMKEAGFLAAHSSMSADEALRW
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
MNEINADATLPQPVTYTPQLIDRNLTALDSSLSRRISLPPELIYLVRFPLGVRSAMSKLG
HHHCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHC
ATVSSRSAAADMIGIAEPDTALGIRHVAWVKERGLPFGLDPREQSEVGARL
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure 
AEEPVPRGRIRRTMPLAGFTARAAGGRLVAGLREKAGDTGAVDRFHHRTAERYTELLGH
CCCCCCCCHHHHCCCCCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
SKGVLMKAGQIFSSIDMNGADGGISPYEQALTRLQTQSPPMAPALARSVLESELRVPTSQ
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
AYASFTDDPISAASIGQVHRATLHDGRDVVVKIQYPGVAQAIQDDLANTELVTTFLRVTF
HHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHH
ALLDRRYAIDLPATARDISAQIKEELDYKQEAENISAFHRLFAGHPFIRVPQAVPELSTR
HHHHCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHCCCCCC
RVLTMTYVDGIDWTEAQQADQELKNTWAEALWRFSLAPLQHACAFYTDLHPGNYRFGLDG
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
SLGIVDFGSVKNLRESHRLAWIRMVAASIQQRPADLHSTMKEAGFLAAHSSMSADEALRW
CCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHH
MNEINADATLPQPVTYTPQLIDRNLTALDSSLSRRISLPPELIYLVRFPLGVRSAMSKLG
HHHCCCCCCCCCCCCCCHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHC
ATVSSRSAAADMIGIAEPDTALGIRHVAWVKERGLPFGLDPREQSEVGARL
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]