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The map label for this gene is mutT1 [H]

Identifier: 169630372

GI number: 169630372

Start: 3330283

End: 3331218

Strand: Direct

Name: mutT1 [H]

Synonym: MAB_3291

Alternate gene names: 169630372

Gene position: 3330283-3331218 (Clockwise)

Preceding gene: 169630371

Following gene: 169630376

Centisome position: 65.72

GC content: 62.29

Gene sequence:

>936_bases
GTGCCCGATCCGATCTCCCGGACCGGTGCGGCGGTCCTTGCCGCCGGAGCCGCGCTCTGGCGGCATCAGGAGCACCCTGA
GCAGGACAACGCTGCCGGCGCCATCGAAGTAGCGCTGGTACACCGACCACGATACGACGACTGGTCACTACCCAAGGGAA
AACTCGACCCCGGAGAAACGGCGGCGATCGCCGCCGTCCGCGAGATCGCCGAGGAGACGGGATTTACCGCCAGGCTCGGC
CGGCGATTGCCCTCGGTGAGTTATCCGGTCAGCCAAGGCACCAAACGCGTCAAATACTGGGCAGCAGAAGCTTTGGACGG
CAAGTTCGAAGCCAACGACGAAGTAGATGAGCTTCGATGGCTACCGGTAAAAGATGCGATCAAGACGGTCAGCTATGCCG
TTGATCGGAAAGTGCTACGAAACTTCGCAAAGCACCAAATTGATACTCGGACATTAATCATTGTGCGGCACGCAAAGGCC
GGGCGAAAAGAGCGCTATTCGGGCGATGACACCTTGCGCCCGCTGGACAAAAAAGGCCGTGCCCAAGCCGAGGCGCTCAC
CGGCCAACTACTTGCCTTCGGTGCCAGCGCTATTCACGCCGCCGATAGATTGCGCTGCCGACAGACTGTGGAACCGCTTG
CCGAGGAGCTGAACACGGTGATCTTCAGCGAGCCCGCGCTCAGCGAGGAGGCCTACTGGGCCGACCGCAAGCGCGCGCAC
CGCAGAGTTCTTGAAATCGCCGAGTTGGACGGCATCCGGGTGCTGTGTACACAAGGCAAGGTCATACCGGATCTCATCGA
GTGGTGGGCACAGCGCGACGGGGTCCGCCCCGATAAGTCACGCAACCGCAAGGGCAGCATGTGGGTGCTGTCGATGCGCG
GCCAGAAACTGCTGGCCGCAGACCATCTGGACAGCCCGCTGCCGGCGGGCAGCTGA

Upstream 100 bases:

>100_bases
GTGCGCGACCATCAGGTGGAGATGATGAAACGGCACCGCTCGCAGACATGACCTAGACCAGGTCCTCCCGGTCGAACAAC
TCTCCCCAGAAGGAGCTTTC

Downstream 100 bases:

>100_bases
CGGAGACCCCCAAAAAAGCAACATCGGGCCCCACCCTGAGGTGGGACCCGATGTTGTCGGGAAACTACTTGCGGCCCTTC
TTGGCCGGAGCCTTCTTGGC

Product: MutT/NUDIX hydrolase

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MPDPISRTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHRPRYDDWSLPKGKLDPGETAAIAAVREIAEETGFTARLG
RRLPSVSYPVSQGTKRVKYWAAEALDGKFEANDEVDELRWLPVKDAIKTVSYAVDRKVLRNFAKHQIDTRTLIIVRHAKA
GRKERYSGDDTLRPLDKKGRAQAEALTGQLLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRAH
RRVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWVLSMRGQKLLAADHLDSPLPAGS

Sequences:

>Translated_311_residues
MPDPISRTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHRPRYDDWSLPKGKLDPGETAAIAAVREIAEETGFTARLG
RRLPSVSYPVSQGTKRVKYWAAEALDGKFEANDEVDELRWLPVKDAIKTVSYAVDRKVLRNFAKHQIDTRTLIIVRHAKA
GRKERYSGDDTLRPLDKKGRAQAEALTGQLLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRAH
RRVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWVLSMRGQKLLAADHLDSPLPAGS
>Mature_310_residues
PDPISRTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHRPRYDDWSLPKGKLDPGETAAIAAVREIAEETGFTARLGR
RLPSVSYPVSQGTKRVKYWAAEALDGKFEANDEVDELRWLPVKDAIKTVSYAVDRKVLRNFAKHQIDTRTLIIVRHAKAG
RKERYSGDDTLRPLDKKGRAQAEALTGQLLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRAHR
RVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWVLSMRGQKLLAADHLDSPLPAGS

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX; PF00300 PGAM [H]

EC number: NA

Molecular weight: Translated: 34627; Mature: 34496

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPISRTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHRPRYDDWSLPKGKLDPGET
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHH
AAIAAVREIAEETGFTARLGRRLPSVSYPVSQGTKRVKYWAAEALDGKFEANDEVDELRW
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCHHHHHHHHHHHCCCCCCCCCCHHHHEE
LPVKDAIKTVSYAVDRKVLRNFAKHQIDTRTLIIVRHAKAGRKERYSGDDTLRPLDKKGR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCCCCCCCCCCCCH
AQAEALTGQLLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RRVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWVLSMRGQKLLAA
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEEH
DHLDSPLPAGS
HCCCCCCCCCC
>Mature Secondary Structure 
PDPISRTGAAVLAAGAALWRHQEHPEQDNAAGAIEVALVHRPRYDDWSLPKGKLDPGET
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHH
AAIAAVREIAEETGFTARLGRRLPSVSYPVSQGTKRVKYWAAEALDGKFEANDEVDELRW
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCHHHHHHHHHHHCCCCCCCCCCHHHHEE
LPVKDAIKTVSYAVDRKVLRNFAKHQIDTRTLIIVRHAKAGRKERYSGDDTLRPLDKKGR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHCCCCCCCCCCCCCCCH
AQAEALTGQLLAFGASAIHAADRLRCRQTVEPLAEELNTVIFSEPALSEEAYWADRKRAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
RRVLEIAELDGIRVLCTQGKVIPDLIEWWAQRDGVRPDKSRNRKGSMWVLSMRGQKLLAA
HHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCEEEEH
DHLDSPLPAGS
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]